Urticaria (Hives) and Angioedema Flashcards

1
Q

Episodes of hives that last for ___ are considered acute

A

Less than 6 weeks

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2
Q

Episodes of hives that last for ___ are considered chronic

A

Occur at least 2x a week for >6 weeks

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3
Q

Acute urticaria and angioedema are often caused by and allergic ___-mediated reaction

A

IgE

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4
Q

Lesions of physical urticarias last for ___, in which the inciting stimulus is only briefly encountered

A

1-2 hours

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5
Q

Lesions that burn more than itch, last >24h, do not blanch, or are associated with bleeding into the skin (purpura) are suggestive of

A

Urticarial vasculitis

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6
Q

Diagnosis of cold urticaria is confirmed by

A

Challenge testing for an isomorphic cold reaction by holding an ice cube in place on patient’s skin for 4 minutes

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7
Q

Positive test result for cold urticaria

A

Development of urticarial lesion about 10 mins after removal of ice cube and upon rewarming of chilled skin

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8
Q

Urticaria characterized by onset of small punctate wheals surrounded by a prominent erythematous flare associated with exercise, hot showers, and sweating

A

Cholinergic urticaria

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9
Q

T/F Chronic idiopathic urticaria and angioedema is characterized by normal routine lab values and no evidence of systemic disease

A

T

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10
Q

Urticaria associated with presence of antithyroid antibodies

A

Chronic urticaria

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11
Q

Most common causes of acute urticaria

A

Drugs and food

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12
Q

Skin biopsy for diagnosis of possible urticarial vasculitis is recommended for urticarial lesions that

A

1) Persist at the same location for >24h 2) With pigmented or purpuric components 3) Burn more than itch

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13
Q

MC skin manifestation of mastocytosis and may occur as an isolated skin finding appearing as small, yellow-tan to reddish brown macules or raised papules that urticate on scratching

A

Urticaria pigmentosa

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14
Q

What is Darier sign

A

Redness, swelling and itchiness of skin (urtication) after being scratched or rubbed

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15
Q

T/F Acute urticaria is a self-limited illness

A

T

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16
Q

Management of acute urticaria

A

1) Antihistamines 2) Avoidance of any identified provocateur

17
Q

Hereditary angioedema is an inherited disease caused by low levels of

A

Plasma protein C inhibitor

18
Q

MC symptom of hereditary angioedema (HAE)

A

Cutaneous, non-pitting and non-pruritic edema not associated with urticaria

19
Q

Most feared complication of HAE

A

Laryngeal edema