URTI

Question 1

Influenza: Dosing for PO Oseltamivir

Answer 1

75mg BD x 5 days

Question 2

Pharyngitis: no penicillin allergy

Answer 2

PO penicillin 250mg q6h or
PO amoxicillin 500mg q12h
x 10d

Question 3

Pharyngitis: non-severe penicillin allergy

Answer 3

PO cephalexin 500mg q12h x 10d
**CANNOT use if amoxicillin allergy

Question 4

Pharyngitis: non-severe penicillin allergy

Answer 4

• PO azithromycin 500mg once daily
• PO clarithromycin 250mg q12h
• PO clindamycin 300mg q8h

Duration: 10 days (5 days for azithromycin)

Question 5

Sinusitis: 1st line (no penicillin allergy)

Answer 5

PO amoxicillin 500mg q8h OR PO augmentin 625mg q8h

Duration: 5 - 7 days (adults)

Question 6

Sinusitis: non-severe penicillin allergy

Answer 6

PO cefuroxime 500mg q12h

Duration: 5 - 7 days (adults)

Question 7

Sinusitis: severe penicillin allergy

Answer 7

PO levofloxacin 500mg daily OR
PO moxifloxacin 400mg daily

Duration: 5 - 7 days (adults)

Question 8

Likely pathogen for pharyngitis

Answer 8

S. pyogenes

Question 9

Likely pathogen for rhinosinusitis

Answer 9

Commonly streptococcus pneumoniae & H. influenzae;
Some strep pyogenes, moraxella catarrhalis, aerobic bacteria

Question 10

How to differentiate btw viral VS bacterial sinusitis?

Answer 10

Based on clinical presentation

Question 11

When to treat as bacterial sinusitis?

Answer 11

Any 1 of the following:
- Symptoms persist for > 10 days w/o clinical improvement
- Symptoms are severe (Fever > 39, purulent nasal discharge, or facial pain lasting > 3 consecutive days)
- Symptoms worsen (new-onset fever, headache, nasal discharge) after an initial period of improvement for more than 3 days (5-6 days)