Urology & Tumors of the Urinary Tract

Question 1

Clear Cell carcinoma - Epidemiology

Answer 1

Most common type of renal cell carcinoma (70-80% of all renal cell cancers)

3rd most common urologic malignancy

Question 2

Characteristics of clear cell carcinoma

Answer 2

Arises from renal cortex, most often presents as a single tumor

Has a propensity to invade the renal vein and can extend into the IVC and heart

Question 3

Fuhrman’s Criteria

Answer 3

Nuclear grading classification for clear cell carcinoma tumors

Varies from 1-4 with grades 1-2 carrying a better prognosis than grades 3-4

Question 4

Papillary carcinoma - Epidemiology

Answer 4

10-15% of all renal cell cancers

Question 5

Characteristics of papillary carcinoma

Answer 5

More frequently multifocal (unlike clear cell carcinoma)

Better prognosis than clear cell carcinoma

Question 6

Chromophobe Renal Carcinoma - Characteristics

Answer 6

5% of renal cell cancers

Derived from intercalated cells of collecting duct

Excellent prognosis

Question 7

Collecting duct (Bellini duct) Carcinoma

Answer 7

<1% renal epithelial neoplasms

Arise from collecting duct cells in the medulla

Poor prognosis