Pathology Flashcards
1
Q
Components of the filtration barrier - 3
A
- Fenestrated endothelial layer - prevents filtration of blood cells and platelets
- Basal lamina - highly negatively charged; prevents filtration of molecules 60-70k Daltons and larger
- Filtration slits between podocytes
2
Q
2 cell types of collecting tubule/duct
A
Principal Cell
Intercalated Cell
3
Q
Principal Cell - Function
A
Reabsorbs Na+ from the collecting tubule lumen in exchange for K+ secretion
4
Q
Intercalated Cell
A
Secrete H+ and reabsorb HCO3-
5
Q
Juxtaglomerular Complex (JGA/JXA)
A
Modified smooth muscle cells in the wall of the afferent arteriole; secrete renin
