Urology Drugs

Question 1

what is doxazocin and how does it work

Answer 1

Alpha blocker
selective for alpha1-adrenoreceptor
found in smooth muscle, vessels, urinary tract
blockade causes relaxation, reduced resistance to bladder outflow

Question 2

indications for doxazocin use

Answer 2

1st line in prostatic hyperplasia, where lifestyle changes are insufficient
add on treatment in resistant hypertension

Question 3

side effects of doxazocin

Answer 3

prominent first dose hypotension

postural hypotension, dizziness, syncope

Question 4

what class of drug is finasteride?

Answer 4

5-alpha reductase inhibitor

Question 5

how does finasteride work

Answer 5

inhibits the enzyme that converts testosterone to dihydrotestosterone
over time leading to reduction in size of prostate

Question 6

what are the side effects of finasteride?

Answer 6

anti-androgen activity - impotence, gynaecomastia, reduced libido
hair growth

Question 7

how long may it take for finasteride to have an effect?

Answer 7

up to 6 months