Urology And Nephrology Flashcards

1
Q

Upper Urinary Tract

A

Kidneys- nephrology

Production

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2
Q

Lower Urinary Tract

A

Bladder/urethra- urology

Storage

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3
Q

Functions of Kidney

A
Excrete waste 
Retrieve filtered particles 
Maintain acid/base balance 
Regulate BP 
Stimulate erythrocyte production
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4
Q

Definition of azotemia

A

Abnormal increase in the concentration of non-protein nitrogenous wastes (urea and creatinine) in blood

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5
Q

Pre-renal causes

A
Dehydration 
Hypoadrenocorticism 
Cardiac disease 
Shock 
Hypovolemia
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6
Q

Renal causes

A
(Parenchymal disease) 
Parenchymal disease 
Infections 
Cysts 
Inflammation 
Neoplasia 
Toxins
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7
Q

Post-renal causes

A

Obstructive

Blockage - urethral/bladder or urethral

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8
Q

T/F

Azotemia is not uremia

A

TRUE

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9
Q

Definition of Renal Failure

A

The clinical syndrome that occurs when kidneys are no longer able to maintain:
Regulatory function
Excretory function
Endocrine function
75 % of nephron population is non-functional

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10
Q

Renal Disease Definition

A

The presence of morphological or functional lesions in one or both kidneys, regardless of extent

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11
Q

Uremia definition

A

The constellation of clinical signs and biochemical abnormalities associated with critical loss of functional nephrons

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12
Q

The glomerular filtration rate is directly related to _____________

A

Renal functional mass

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13
Q

Gold Standard test for measuring glomerular function

A

Clearance of radioisotopes with renal scintigraphy

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14
Q

Urea is synthesized in the ______ and excreted by the _________

A

Liver; kidneys

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15
Q

Serum Urea levels are affected by

A
Species/age 
Liver function 
Dietary protein content 
Endogenous protein catabolism 
Renal function
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16
Q

Azotemia does not develop until GFR has decreased to ___________

A

25%

17
Q

SDMA correlates highly with _____ by inulin and increases when there is a _______% decline in GFR

A

GFR ; 40

18
Q

Gold standard for measuring urine concentration

A

Osmolality - measures number of particles in solution

19
Q

Hyposthenuria

A

1.000-1.007

20
Q

Isosthenuria

A

1.008-1.012

21
Q

Minimally concentrated urine

A

1.013-1.030

22
Q

Inadequately concentrated urine

A

1.013 < 1.022

23
Q

Adequately concentrated urine

A

Dogs > 1.030

Cats > 1.035

24
Q

Partial water deprivation test

A

maximal stimulation of ADH release will be present after loss of 5% body weight

25
Q

Reference value for UPC

A

< 0.4 should be < 0.2

26
Q

Hematuria

A

Presence of blood or red blood cells in the urine

27
Q

Pseudohematuria

A

Red to brownish urine without intact RBCs

28
Q

Causes of Hematuria

A

Systemic disorders
Renal
Bladder, ureter, urethra
Genital tract

29
Q

Manifestations of renal disease

A

Systemic signs
Check for history of toxin exposure
Dehydration
Melena/hematemesis/vomiting

30
Q

Urine production rate is

A

1-2 ml/kg/hr minimum

31
Q

Renal carcinoma is more common in _________

A

Dogs (poor prognosis)

32
Q

Renal lymphoma is more common in _______ and affects _________ kidneys

A

Cats ; both

33
Q

Non-neoplastic causes of renomegaly

A
ACUTE URETERAL OBSTRUCTION 
Renal inflammation 
Amyloidosis 
Hydronephrosis 
Polycystic kidney disease 
Portosystemic shunt