Urology Flashcards
The renal artery branches out from the aorta at which vertebral level?
L2
Why is there a presence of perinephric fluid that extends to the pelvis despite an intact gerota’s fascia?
Gerota’s fascia is open inferiorly
What is the normal weight of the kidney?
150 to 160g
How many peristaltic waves per minute are present in the ureter?
4
What is the normal ureter pressure?
30mmHg
What is the normal length of the ureter
28 to 30cm
trace the abdominal course of the ureter
- Renal Pelvis
- Tip of the transverse process of the lumbar vertebra
- Psoas major muscle
- Crosses the GENITOFEMORAL nerve
- Under the gonadal vessel
- Cross the common iliac and external iliac artery
Trace the pelvic course of the ureter (Female)
- cross the posterior ductus deferens (promixal to ureterovesical junction)
- Enters bladder obliquely
- Obliquely enters the bladder wall
Trace the pelvic course of the ureter (Male)
- Anterior to the internal iliac artery
- Posterior to the ovary
- Under the broad ligament
- Behind the uterine vessels
- Obliquely enter the bladder wall
What are the 3 ureteric constrictions
- Ureteropelvic junction
- Crossing the iliac vessel
- Ureterovesical junction
Remember, UIU
What is the true physical constriction of the ureter?
Ureterovesical junction
The ureter is ____ (anterior/posterior) to the iliac vessels
ANTERIOR
Yes. But it is posterior to the uterine artery
Which part of the ureter is the most common site of iatrogenic injury?
Distal third of the ureter
During hysterectomy, ureters are commonly injured during _____
ligation of ovarian and uterine vessels
During APR, ureter is commonly injured during ____
division of the lateral ligaments of the rectum
During pelvic surgery, ureter is commonly injured during ___
attempts to control bleeding
[Management of ureteral injury]
<1/2 of diameter is transected
Primary closure over ureteral stent
[Management of ureteral injury]
> 1/2 of diameter is transected
excision with reconstruction
[Management of ureteral injury]
complete transection
reconstruction is required
What is the normal size of the prostate gland?
4x3x2cm
What is normal weight of the prostate gland?
15 to 18 g
What are the blood supply of prostate gland?
- Inferior vesical
- Middle hemorrhoidal
- Internal pudendal
The reason why prostate CA can metastasize to the spinal cord
Batson plexus
What is the role of fructose that is present in the seminal vesicles?
sperm motility
What is the average growth per year (in grams) of the prostate gland after 50 years of age?
0.5 to 0.8 grams per year
Which zone of the prostate gradually enlarges that causes urinary outflow tract obstruction?
Periurethal zone = transitional zone
What receptors are present in the periurethal zone of the prostate causing urinary outflow tract obstruction
Alpha 1 adrenergic receptos
What is the initial compensatory response of the bladder in BPH?
compensatory muscular HYPERPLASIA
What is the PSA profile of patients with BPH? (decreased or elevated)
Elevated
What is the most sensitive and specific test to confirm presence of bladder outlet obstruction?
Pressure-flow urodynamics
Increased bladder pressure and low flow
What diagnostic test differentiates ureteral stricture from BPH?
Endoscopy
it also gives information on prostatic configuration
[Management of BPH]
IPSS <7
watchful waiting, annual follow up
What drug class helps relax prostatic smooth muscle?
alpha adrenergic receptor blocker
What drug class reduces intra-prostatic DHT levels which may shrink and slow progression of BPH?
5 alpha reductase
What is the percent reduction in prostatic size after 6 months of 5 alpha reductase treatment?
20%
What are the short term complications of Transurethral Resection of the prostate?
- Hyponatremia due to absorption of hypotonic irrigation fluid
- Urinary retention
- Infection
What are the long term complications of Transurethral Resection of the prostate?
- Incontinence
- Impotence
- Retrograde ejaculation
- Bladder neck contracture
- Urethral strictures
Aside from TURP, this surgical method is also effective for prostate glands <30g
Transurethral Incision of prostate
Advantage of Transurethral Incision of prostate over Transurethral resection of the prostate
- Less risk of retrograde ejaculation
- Less risk of impotence
- Less risk of blood loss
What is the surgical management of choice for prostates >80g
Prostatectomy (Retropubic or Suprapubic)
What are the indications for prostatectomy?
- Acute urinary retention
- Recurrent or persistent UTI
- Significant symptoms from bladder outlet obstruction not responsive to medical therapy
- Recurrent gross hematuria of prostatic origin
- Pathophysiologic changes of the kidney, ureter, bladder
- bladder calculi due to obstruction
What is the most common type of prostate CA?
Adenocarcinoma
Common initial site of prostate CA?
periphery
That is why symptoms of urinary obstruction occur late
PSA used as cancer marker for prostate CA is ____ ( sensitive/ specific)?
sensitive
SNNOUT
What is the preferred imaging test for prostate CA?
Transrectal UTZ
A high gleason score means that the prostatic CA is ____ (well/poorly) differentiated?
poorly differentiated
What is the diagnostic method/test used for prostate cancer
Transrectal biopsy
What is the normal weight of the testis?
20g
Which part of the testis are not covered by tunica albuginea?
Dorsal area
Epididymis and dorsal pedicle are attached
The right spermatic vein drains to the _____
directly to the IVC
The left spermatic vein drains to the ____
left renal vein
What maintains the bladder neck and proximal urethra closure?
- Alpha receptor of the bladder neck
- Proximal urethra shares excursions in intraabdominal pressure
- Increase in intraabdominal pressure causes increase in external urethral sphincter muscle contraction and closes distal urethra
Where is the micturition center located?
pons
How many corpora cavernosa are present in the penis?
2
corpus spongiousum = 1
What erectile body of the penis is present in the ventral portion?
Corpus spongiosum
If the patients has initial hematuria, where is the lesion?
Distal to bladder neck
If the patients has terminal hematuria, where is the lesion?
proximal to bladder neck, proximal ureter, trigone
If the patients has total hematuria, where is the lesion?
bladder, ureter, kidney
[Incontinence]
continous, not associated with urgency and stress
Total incontinence
[Incontinence]
leakage of urine associated with increase in abdominal pressure
stress incontinence
[Incontinence]
urinary leakage preceded by the sensation of an urgen need to urinate caused by uninhibited bladder contraction due to infection, bladder CA, neurogenic
urge incontinence
[Incontinence]
overflow of a small amount of urine from a distended bladder
overflow incontinence
What is the RBC finding that is significant in urinalysis?
3/hpf
What is the WBC finding that is significant in urinalysis?
5/hpf
What are normal values of semenalysis?
- Volume 15mL
- 15 million
- 10% motile
- 4% morphology
- 2 abnormal semen analysis
Remember, 15 15 10 4 2
____ is an imaging tool done during cystoscopy that evaluate kidneys, bladder,ureters,
Retrograde pyeloureterography
___ diagnostic tool that reveals the dynamics of micturition and evidence of obstruction or reflux of urine
Voiding Cystourethrogram
Used to see patency of the urethra
___ diagnostic technique used during therapeutic dilatation of narrow arteries; also used to evaluate renal vasculature
Renal arteriography
___ diagnostic technique used for early detection and staging of prostate cancer
Ultrasonography
What is the commonly used imaging technique for imaging urologic neoplasms?
Contrast-enhanced CT scan
Emphysematous pyelonephritis is commonly seen in which patients?
DM patients
___ syndrome
Arthritis, conjunctivitis, non-gonoccocal urethritis
Reiter Syndrome
What is the manifestation of chronic prostatitis with sterile prostatic secretion
Prostatodynia
Genital TB most commonly involves which part of the mate Genitourinary Tract?
Epididymis
What type of nephrolith is associated with urea-splitting bacteria or proteus spp?
struvite stone
[Location of ureteral stone]
flank pain radiating to the groin
proximal 1/3 of ureter
[Location of ureteral stone]
anterior lower quadrant pain
stone in the middle third of ureter
[Location of ureteral stone]
presence of bladder irritative symptoms
stone in the distal third of the ureter
[Nephrolithiasis]
A basic urine pH >7 is associated with what organism
urea-splitting organism
What is the hounsfield of water
0 HU
What is the hounsfield of air
minus 1000 HU
What is the hounsfield of bone
plus 1000HU
Size of stone that rarely pass spontaneously
stones >6mm
Nephrectomy is indicated if renogram of a stone-bearing kidney has a renal function of _____
<20%
Drugs that are stone-provoking
- Acetazolamide
- Calcium supplements or Vitamin D
- Vitamin C
Nephrolith formed that is associated with excesive vitamin C intake
Calcium oxalate stone
What are the complications of extracorporeal shock wave lithotripsy?
- Direct injury to kidney
2. Streinstrasse (incomplete stone fragmentation)
Location of stone in the kidney that is associated with lowest stone free rates
Lower pole
Type of nephrolith that cannot be broken down by SWL
Cystine stone
Surgical management of large, complex renal or ureteral calculi
Percutaneous Nephrectolithotomy
What is the rationale behind leaving a ureteral stent after ureteroscopy
To prevent distal migration of stone fragment during intra-corporeal lithotripsy
What are the common causes of upper tract ureteral obstruction
- Ureteral stone (most common)
2. Malignancy
Most common causes of lower tract obstruction
- Bladder outlet stone or mass
- Urethral stones, stricture
- Prostate: BPH, Ca
What are the signs and symptoms of Lower tract obstruction
WINSURF
Weak stream Intermittency Nocturia Straining Urgency Retention Frequency
What is the triad of renal cell carcinoma
- Pain
- Mass
- Hematuria
___ syndrome refers to renal cell CA + hepatic cell dysfunction
reversible hepatic cell dysfunction with removal of RCCA
Stauffer’s syndrome
What imaging is able to determine the extent of vascular involvement in patient with RCCA
MRI
What is removed in radical nephrectomy for patients with RCCA?
- Excision fo kidney
- Gerotas fascia
- Perinephric fat
[Bosniak Classification]
Hairline thin wall, no septa
Bosniak 1
Malignancy = 1.7%
[Bosniak Classification]
few hairline thin septa and fine calcifications; short segment, slightly thickened <3cm
Bosniak II
Malignant = 18.5%
[Bosniak Classification]
multiple hairline septa, septa can have calcifications >/3cm
Bosniak IIF
Malignant = 18%
[Bosniak Classification]
indeterminate cystic masses, thickened irregular or smooth walls or septa
Bosniak III
Malignant = 33%
[Bosniak Classification]
Clearly malignant; contains enhancing soft-tissue components
Bosniak IV
malignant = 92.5%