Urology Flashcards

1
Q

Suspect this in a pt w/ very severe testicular pain of sudden onset, but no fever, pyuria, or history of recent mumps. The testis is swollen, exquisitely tender, “high riding,” and with a “horizontal lie.” The cord is not tender.

A

Testicular torsion. Dire emergency

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2
Q

Consider this in young men old enough to be sexually active, who presents with severe testicular pain of sudden onset. There is fever and pyuria, and the testis although swollen and very tender is in the normal position. The cord is also very tender.

A

Acute Epididymitis.

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3
Q

What should you do for a person with Acute Epididymitis

A

Tx w/ Antibiotics. The possibility of missing a diagnosis of testicular torsion is so dreadful that sonogram is done to rule it out.

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4
Q

Suspect this in a pt who is being allowed to pass a ureteral stone spontaneously and who suddenly develops chills, fever spike (104° or 105° F), and flank pain

A

The urinary tract may be obstructed and infected. Dire emergency.

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5
Q

How do you treat an obstructed and infected urinary tract

A

IV antibiotics, immediate decompression of the urinary tract above the obstruction.

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6
Q

Treatment for pyelonephritis

A

Hospitalization, IV antibiotics (guided by cultures), and urologic workup (IVP or sonogram)

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7
Q

Suspect this in older men who have chills, fever, dysuria, urinary frequency, diffuse low back pain, and an exquisitely tender
prostate on rectal exam.

A

Acute bacterial prostatitis

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8
Q

Tx for acute bacterial prostatitis

A

IV antibiotics, and don’t do any more rectal exams. Prostatic massage could lead to septic shock.

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9
Q

Why not do circumcisions on kids with hypospadias

A

they need the foreskin for the plastic surgery to fix it

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10
Q

Tx for vesicoureteral reflux

A

long term antibiotics until he grows out of the problem

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11
Q

Suspect this in a little girl who voids normally but seems to always be wet with urine

A

low implantation of a ureter. correct with surgery.

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12
Q

First step in workup for hematuria suspicious for cancer

A

CT scan, then cystoscopy

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13
Q

suspect in pt w/ hematuria, flank
pain, and a flank mass. Also possibly produce hypercalcemia, erythrocytosis,
and elevated liver enzymes.

A

Renal cell carcinoma

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14
Q

Bladder Cancer has a super close assc w/ what

A

smoking

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15
Q

Presentation of prostate cancer

A

Most are asymptomatic and have to be sought by rectal exam (rock-hard discrete nodule) and prostatic specific antigen (PSA; elevated levels for age group).

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16
Q

Presentation of testicular cancer

A

painless testicular mass

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17
Q

Tx of testicular cancer

A

Because benign testicular tumors are virtually nonexistent, biopsy is done with a radical orchiectomy by the inguinal route. Blood samples are taken pre-op for serum markers (a-fetoprotein and b-HCG]), which will be useful for follow-up.

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18
Q

Workup for suspected prostate cancer

A

Transrectal needle biopsy (guided by sonogram when discovered by PSA) establishes diagnosis. CT helps assess extent and choose therapy. Surgery and/or radiation are choices

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19
Q

Short term therapy for urinary retention due to prostate hypertrophy? Long term?

A

Short term: indwelling catheter at least 3 days.

Long term: Alpha-blockers. Or 5-alpha-reductase inhibitors for very large glands..

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20
Q

Common kind of post-op urinary retention

A

Overflow incontinence

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21
Q

Suspect this in a middle-age multigravida woman who leaks small amounts of urine during sneezing, laughing, getting out of a chair, or lifting a heavy object. No incontinence at night. Examination shows a weak pelvic floor, with the prolapsed bladder neck outside of the “high-pressure” abdominal area.

A

Stress incontinence

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22
Q

Consider this in a pt w/ flank pain, with
irradiation to the inner thigh and labia or scrotum, and sometimes nausea and
vomiting.

A

Passing ureteral stones

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23
Q

If intervention is necessary for a kidney stone, what is most commonly done?

A

Extracorporeal shock-wave lithotripsy (ESWL). That, and abundant water intake is always indicated.

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24
Q

Most common cause of pneumaturia

A

Almost always caused by fistulization between the bladder and the GI tract, most commonly the sigmoid colon, and most commonly from diverticulitis

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25
Q

First steps when you have a pt w/ pneumaturia

A

Workup starts with CT scan, which will show the inflammatory diverticular mass. Sigmoidoscopy is needed later to rule out cancer. Surgical therapy is required.

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26
Q

How to tell the difference between organic and psychogenic impotence

A

Psychogenic does not interfere with nocturnal erections, organic does

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27
Q

Diagnosis when palpation of the testes reveals a small firm and tender nodule near the head of the epididymis that appears to have a blue discoloration

A

This is the blue dot sign, pathognomonic for testicular or appendix testes torsion

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28
Q

Four Cardinal Symptoms and Signs of Testicular Torsion?

A

Nausea/vomiting, testicular pain duration of less than 24 hours, a superiorly displaced testicle, and an absent cremasteric refl ex.

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29
Q

Gradual onset of testicular pain, most common cause of acute painful hemiscrotum in a child

A

Appendix testes torsion

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30
Q

Tx of testicular torsion

A

Presentation < 6 hours; attempt manual detorsion followed by elective orchiopexy.
>6 hours: surgical detorsion, followed by b/l orchiopexy

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31
Q

Tx of Appendix testes torsion

A

Nonsteroidal anti-inflammatory drugs, ice packs, and scrotal support; uncontrolled pain can be managed with surgical excision of the appendix testes

32
Q

DDX of scrotal mass involving skin

A

Epidermal or pilar cysts; Squamous cell carcinoma

33
Q

DDX of scrotal mass involving epididymis?

A

Epididymitis; Spermatocele; Appendix testes

34
Q

DDX of scrotal mass involving testicle

A

Orchitis; Testicular torsion; Testicular cancer

35
Q

Any painless mass in the testicle is what until proven otherwise

A

Cancer

36
Q

PainFUL mass INSIDE testicle - what is it, and what caused it?

A

Orchitis; most often viral origin, think MUMPS

37
Q

5 main diagnoses to consider in a painFUL scrotal mass

A

Epididymitis (outside testicle) and Orchitis (inside testicle). Testicular torsion and appendix testes torsion are up there too. Finally, incarcerated hernia can be super painful.

38
Q

3 main benign diagnoses in a painLESS testicular mass

A

Spermatocele, hydrocele, varicocele. All separate from the testicle.

39
Q

Think this diagnosis when a patient with a testicular mass, whose mass disappears when he lies down, and reappears when he stands back up.

A

Varicocele. P.S. Also, look for “feels like a bag of worms”. Also “associated with infertility”.

40
Q

In a kid with an undescended testicle, what are they at higher risk for later?

A

Testicular cancer

41
Q

Most common type of testicular cancer

A

Seminoma

42
Q

4 bugs that cause epididymitis

A

Chlamydia trachomatis, Neisseria gonorrhea, E. coli, Pseudomonas

43
Q

What causes gynecomastia in patients with testicular cancer?

A

Choriocarcinoma, a germ cell tumor, is associated with ectopic human chorionic gonadotropin (hCG) production. Elevated hCG can stimulate breast development, leading to gynecomastia.

44
Q

Which side does a varicocele form more often?

A

Left side (left testicular vein drains into the left renal vein at a right angle, while the right testicular vein drains into the IVC at a better angle)

45
Q

Blood markers useful when diagnosed with testicular cancer

A

Alpha-fetoprotein (AFP), beta-HCG, and LDH

46
Q

Biopsy requirements for testicular cancer

A

Don’t do it you might seed the cancer

47
Q

Tx for testicular cancer

A

Ochiectomy (via inguinal incision, not scrotal). Then possible chemo, radiation, and retroperitoneal lymph node dissection.

48
Q

What to suspect when your patient has painless blood in the urine

A

Cancer (bladder), especially when they have risk factors

49
Q

What to suspect when your patient has painful blood in the urine

A

Infection or obstruction, like UTI, pyelonephritis, or nephrolithiasis

50
Q

Suspect this in a patient with acute colicky flank pain that may extend into the groin. The pain is described as colicky, with periods of severe pain during which the patient will not be able to stay still and will shift positions in an attempt to relieve their pain, followed by temporary resolution of the pain

A

Nephrolithiasis

51
Q

Consider this in a patient with flank pain, abdominal mass, and hematuria

A

Kidney cancer; however, all 3 are only present in ~10-15% of cases

52
Q

Most common type of renal stone

A

Calcium oxalate

53
Q

Most likely places for a renal stone to get stuck

A

At points of narrowing in the GU tract: the ureteropelvic junction (UPJ), where the ureter crosses the iliac vessels, and the ureterovesical junction (UVJ)

54
Q

Most common type of renal cancer

A

Renal Cell Carcinoma (RCC).

P.S. Of those, 70% are clear cell, 15% papillary, 5% chromophobe.

55
Q

Most common location of renal cancer metastasis

A

Lung

56
Q

Most common type of bladder cancer

A

Urothelial cell carcinoma

57
Q

Most common type of prostate cancer

A

Prostatic adenocarcinoma

58
Q

First step in management for a pt w/ hematuria

A

Urinalysis. Can also do a urine dipstick.

59
Q

What, after urinalysis, is the next step in workup for a pt w/ hematuria?

A

Microscopic urinalysis

60
Q

Best diagnostic test for urolithiasis

A

non-contrast helical CT-scan. For pregnant ladies, ultrasonography

61
Q

What Is the Best Management for Nephrolithiasis? How Does the Size of the Stone Change Management?

A

Renal stones <5 mm pass on their own and should be managed with supportive therapy unless the patient is septic, has a solitary kidney, or has uncontrolled pain. Alpha-blockers such as tamsulosin may also be given to relax the ureteral wall. Stones between 5 and 9 mm should be managed using clinical judgment. Stones larger than 9 mm are unlikely
to pass spontaneously and will therefore require more invasive treatment.

62
Q

What is a radical nephrectomy?

A

Removal of the kidney, perinephric fat, Gerota’s fascia, ureter, lymph nodes, and possibly the ipsilateral adrenal glands

63
Q

Treatment of urothelial carcinoma of the bladder

A

Initially transurethral resection for diagnosis and staging. Small superficial tumors can be treated with complete transurethral resection and potentially intravesical chemotherapy (mitomycin) or immunotherapy (bacillus Calmette-Guérin infused via urinary catheter). UCC has a high recurrence rate, and patients need to be closely monitored. The standard of care for nonmetastatic tumors that invade the detrusor muscle is radical cystectomy with urinary diversion.

64
Q

What is a radical cystectomy?

A

The removal of the entire bladder and pelvic lymph nodes. In a male, the prostate and seminal vesicles are also removed. In a female, the cervix, uterus, fallopian tubes, and part of the vagina are also removed

65
Q

What Is a Radical Prostatectomy? Which Patients Are Appropriate Candidates for This Procedure?

A

Removal of the prostate and seminal vesicles. Patients with disease contained to the prostate and a life expectancy of at least 10 years are good candidates

66
Q

What procedure should you do when you see blood at the meatus of the urethra/

A

Retrograde cystourethrogram

67
Q

When you see a BUN/Creatinine ratio > 20 and history of hypovolemia or hypoperfusion, what should you suspect?

A

Prerenal AKI

68
Q

Common nephrotoxic drugs

A

intravenous contrast agents, aminoglycosides (e.g. gentamicin), amphotericin, cisplatin, cyclosporine, and NSAIDs.

69
Q

When you see a BUN/Creatinine >20 and evidence of hydronephrosis, what should you suspect?

A

postrenal AKI

70
Q

Virchow’s triad

A

Stasis, epithelial injury, hypercoagulable state. Makes pts susceptible to venous thromboembolic events

71
Q

If you suspect PE, what should you do first?

A

Start heparin right away. Then do a CT.

72
Q

Suspect this in a patient who on DRE you feel a smooth rubbery prostate

A

Benign prostatic hypertrophy (BPH)

73
Q

Treatment for benign prostatic hypertrophy, short term and long term

A

Short term: alpha blockers (terazosin, doxazosin, tamulosin, alfuzosin)
Long term: alpha-5-reductase inhibitors (finasteride)

74
Q

Treatment for an organic cause of impotence, like atherosclerosis or diabetes

A

Phosphodiesterase inhibitors (sildenafil, verdanafil)

75
Q

treatment for bacterial postatitis

A

fluoroquinolones

76
Q

people with klinefelters syndrome (47, XXY) are at increased risk for what urologic cancer?

A

Germ cell tumors