Urology Flashcards
What are the common causes of haematuria?
Nephritic syndrome
Renal, ureteric or bladder or prostate cancer
Trauma
Renal and ureteric and bladder stones
TB
Pyleonephritis
Schistosomiasis
Urethritis
Strictures
BPH
Epidymitis
Menses
What are the risk factors for haematuria?
Above 60
Smoking
Worked with paint, dyes, metals or petroleum
Recurrent UTI
FHx of bladder cancer
Schistosomiasis prevalent
How might you examine a patient with haematuria?
Abdo - tenderness or masses, urinary retention
DRE - prostate
What are the primary Investigations for haematuria?
Blood tests, urinalysis, midstream urine sample for culture, upper tract imaging and flexible cystoscopy
What other symptoms should be assessed with haematuria?
Rigours
Fever
lethargy
What results in renal colic?
Acute ureteric obstruction - usually calculus or blood clots
What can acute ureteric obstruction lead to?
Acute renal failure or pyonephrosis
What type of pain Is renal colic?
From loin to groin
Peristalytic movement
How do you respond to pyonephrosis.
Urological emergency. Decompress
What is the common presentation of renal colic!
Sweat, pale, restLess, N+V
How is upper urinary tract obstruction diagnosed?
CT or USS
Diuretic renography (MAG3)
How is an upper urinary tract drained?
Nephrostomy
JJ stent
Anagelesia
High fluid intake
ESWL
PCNL
What are the causes of stress UI?
Weakness in pelvic floor muscle - post partum, constipation, obesity, post menopausal, pelvic surgery
What are the causes of urge UI?
Neurogenic caused - infection, malignancy or idiopathic, medication - cholinesterase inhibitors
Mixed UI
Stress and urge
What are the causes of overflow UI!
Prostatic hyperplasia, spinal cord injury or congenital defects
What are the causes of continuous UI?
Ectopic ureter or bladder fistula
What investigations should be performed for incontinence?
Bladder diaries
Midstream urine dipstick - infection or haematuria
Post void bladder scans
Urodynamics assessment
Cytoscopy
What is the conservative management of UI?
Stress: Pelvic floor muscle training and Duloxetine (ssri)
Urge - anti muscularis drugs and bladder training
What is the surgical management of UI?
Urge - botulinum toxin A injection, percutaneous sacral nerve stimulation, augmentation cystoplasty (whereby a detubularised segment of bowel is inserted into the bladder wall to increase bladder capacity), or urinary diversion via ileal conduit.
Stress - tension free vaginal tape, open colposuspension (involving elevation of the bladder neck and urethra through a lower abdominal incision), intramural bulking agents, or an artificial urinary sphincter
How should a testicular lump be inspected?
the Site, Size, Shape, Symmetry, Skin changes, and any Scars present.
Obstructive uropathy
How should you palpate a testicular lump?
Tenderness, Temperature, Transillumination, Consistency, Attachments, Mobility, Pulsation, Fluctuation, Irreducibility, Regional lymph nodes, and the Edge.
What investigations should be taken for a scrotal lump?
USS, blood tests (tumour markers - LDH, AFP, beta -hCG)
What are the possible causes of testicular lump?
Extra testicular - hydrocoele (fluid between layers of tunica vaginalis, transilluminate), varicoele (abnormal dilation of pampnifork plexus, bag of worms), epididymal cysts (fluid filled sacs from epididymis), epididymitis(usually STI), inguinal hernia (into scrotum via external inguinal ring entering inguinal canal or hesselbach)
Testicular - cancer - painless lumps, does not transillumiate, irregular, testicular torsion (twisting of testis on spermatic cord, bell clapped deformity - high attachment of tunica vaginalis, orchitis
What is a medical emergency!
Testicular torsion
What is the treatment for testicular cancer?
radical inguinal orchidectomy
what parts of a history are important for scrotal lumps?
time of onset
associated sx
previous episodes
how should a scrotal lump be inspected?
Site
Size
Shape
Symmetry
Skin changes
Scars
how should a scrotal lump be palpated?
1) Palpate testis, epidiymis and vas deferens
2) Tenderness, temperature and transillumination
3) CAMPFIRE - Consistency, Attachments, Mobility, Pulsation, Fluctuation, Irreducibility, Regional lymph nodes and Edge
what is the first line investigation for a scrotal lump?
USS of scrotum
which investigations are required if testicular cancer is suspected?
NO BIOPSY - risk of seeding cancer
on other factors and histopathology of testis following orchidectomy
LDH and AFP and beta-hCG can be used
what are the differentials for scrotal lump?
extra testicular - hydrocoele, varicocoele, epidiymal cysts, epididymitis, inguinal hernia
testicular - tumour, torsion, benign lesions, orchitis
hydrocoele - definition, management
abnormal collection of peritoneal fluid between the visceral and parietal parts of tunica vaginalis
- painless fluctuant swellings, transilluminate..can get painful and require surgery
- can be congential requiring ligation
- or idiopathic or secondary to trauma, infection or malignancy..USS
varicoele - definition, management, red flag signs
abnormal dilation of the pampiniform venous plexus within spermatic cord..bag of worms, disappear lying flat
found on left side usually - spermatic veins drain into left renal vein (smaller) compared to IVC on right
- can result in infertility, testicular atrophy…semen analysis
red flag signs = acute, R sided, remain lying flat - embolisation and ligation of veins, but if asymptomatic - no treatment
epidiymal cysts
benign fluid filled sacs arising from epididymis, will transilluminate
no tx
epididymitis
inflammation of the epididymis
unilateral acute onset pain, swelling, erythematous, fever, dysuria, haematuria, urethral discharge
pain relieved on elevation of testis - prehn’s sign
STI or enteric organisms - oral abx and analgesia
inguinal hernia
passes into scrotum via external inguinal ring(through inguinal or hesslebach’s first)..run alongside spermatic cord
cannot palpate its superior surface and cough may exacerbate swelling
testicular tumour
painless lumps in tesis
firm, irregular mass, do not transilluminate
USS, tumour markers, radical inguinal orchidectomy + chemo
testicular torsion
twisting of testis on spermatic cord occludes testicular and cremasteric arteries..ischaemia and testicular infarction
acute, unilateral, N+V
may be associated with bell clapper deformity - high attachment of tunica vaginalis resulting in rotation
tender, swollen, loss of cremasteric reflex
EMERGENCY - surgical exploration..untwisted and return of vascularity then orchidectomy if infarcted
give 4 examples of benign testicular lesions
benign leydig cells tumours, sertoli cell tumours, lipomas, fibromas
orchitis
inflammation of testis
main causes - viral (mumps)
rest and analgesia
which investigations are required for acute scrotal pain
urine dipstick - and requires microscopy culture sensitivity
urethral swab - STI
blood test - FBC, U and E, CRP
USS of scrotum
what are some causes of referred scrotal pain?
branches of genitofemoral and ilioinguinal nerve - anterior and pudendal and posterior femoral cutaneous nerve - posteriot
…ureteric stones
what is the biggest complication of acute-on chronic urinary retention?
post obstructive diuresis
what are some causes of urinary retention?
BPH, urethral strictures, prostate cancer, UTI, constipation (compress urethra), anti-muscarinics or spinal/epidural, peripheral neuropathy, MS or parkinsons (Upper motor neurone diseases)
what are the clinical features of urinary retention?
acute suprapubic pain
unable to micturate
palpable, distended bladder
PR exam - prostate
associated fevers or lethargy - infective
which investigations are required for acute urinary retention?
post void bladder scan - volume of retained urine
FBC, CRP, UE
after catheterisation - a catheterised specimen of urine assessed for infection
USS - hydronephrosis
hydronephrosis
as intravesicular pressure increases and becomes too high, counteracts the anti reflux mechanism of bladder and ureter —> hydroureter and hydronephrosis…deranged renal function, renal scarring, CKD
how is BPH treated?
tamsulosin - alpha receptor antagonist, relaxes smooth muscle at bladder neck and within prostate
what is the most common cause of chronic urinary retention in men?
BPH, or urethral strictures or prostate cancer
what are the most common causes of chronic urinary retention in women?
pelvic prolapse - cystoele, rectocele or uterine prolpase, pevlic masses such as large fibroids
what is the management of chronic urinary retension?
high post void volumes - post obstructive diuresis monitoring
long term catheter
treat underlying cause
what is the most common complication of chronic urinary retention?
UTI due to urinary stasis, or CKD
what is the difference between visible and non visible haematuria?
visible - naked eye
non visible - urine dipstick or urine microscopy
what are some differentials for haematuria?
UTI,renal cancer, renal calculi, prostate cancer, BPH
how is the degree of haematuria quantified?
pink v dark red
presence of clots or not
timing in the stream - if terminal (at end), then bladder irritation but if total - bladder or Upper tract
what are important questions in the history for haematuria?
associated sx - LUTS, fever, rigor, suprapubic or flank pain, weight loss, recent trauma
smoking - urological malignancies, industrial work - bladder cancer, or recent travel (schistosomiasis)
which examinations are required for haematuria?
DRE, abdo, external genitalia
which initial investigations are required for haematuria?
urinalysis - presence of nitites and leukocytes - infection
FBC, UE, clotting
PSA
urinary protein levels and referral to nephrology
what are the nice guidlines for urgent referral to urological service for haematuria?
> 45
unexplained visible without UTI or visible that persists are successful treatment of UTI
> 65
unexplained non visible haematuria, dysuria, raised WCC
what is the gold standard investigation for assessing lower urinary tract?
flexible cystoscopy, with local anaesthetic for further assement or follow up for proven malignancy