Urology Flashcards
Short term complications of UTI
Sepsis, renal abscess, AKI
Long term complications of UTI
Renal scarring, recurrent infection, impaired renal function, hypertension, ESRD, preeclampsia
UTI testing in acutely ill children: age and appropriateness of testing
1) Any child on antibiltics already: test (for UTI)
2) < 3 months: test
3) 3 to 24 months: fever + high risk: test
4) > 24 months: girl/uncircumcised boy with sx: test
Criteria to diagnose UTI in children
Pyuria (LE on UA or WBC on microscopy)
And
Significant bacterial growth on culture:
1) suprapubic aspiration: 10- 50,000 cfu
2) bladder catheterizatio: 1000 to 50,000 cfu
3) midstream clean catch: 10,000 to 100,000
When to get KUB US and voiding cystourethrogram (VCU) in peds?
1) atypical UTI: KUB US—if abnormal— VCU
2) < 24 months first UTI: KUB US—if abnormal— VCU
3) < 24 months recurrent UTI: VCU
4) > 24 months recurrent UTI: KUB US—if abnormal— VCU
Antibiotics in UTI peds: dosage and max
Amoxicillin/ Augmentin
Cefixime
Cefuroxime axetil
Cephalexin
Nitrofurantoin
Bactrim
Amoxicillin/ Augmentin:
25 to 50 mg/kg/day TID, max: 500 mg/dose
Cefixime
8 mg/kg/day Qday, max: 400 mg/dose
Cefuroxime axetil
20 to 30 mg/kg/day BID, max: 500 mg/dose
Cephalexin
50 to 100 mg/kg/day BID to QID, max: 500 mg/dose
Nitrofurantoin
5 to 7 mg/kg/day QID, max: 100 mg/dose
Bactrim < 24 months
6/30 to 12/60 mg/kg/day BID, max: 160 mg/dose (of TMP
Bactrim > 24 months
8/40 mg/kg/day BID, max: 160 mg/dose (of TMP)
Chronic urinary retention
PVR volume greater than 300 ml on 2 separate occasions and lasting 6 months
Suprapubic catheter advantage
Improve patient comfort
Decrease bacteriuria
Decrease need for catheterization for up to 14 days
silver alloy coated and abx impregnated catheters not advantageous
Alpha blocker — catheter?
In urinary retention, initiate alpha blocker at time of catheter insertion or at least before removal— improve successful voiding trial
(After catheter insertion, continous void for 3 days then remove and voiding trial)
MCC of urinary retention
BPH
MCC (2) of iatrogenic urinary retention
Postop
- Risk with older age and prescence of UTI sx
- preop alpha blocker decreased risk
Meds:
Anticholinergics (MCC): block parasymp to detrusor- impair contractility
Alpha adrenergic: increase tone in prostate and bladder neck
CCB: reduce smooth muscle contractility in bladder
NSAIDS: inhibit prostaglandin synthesis- decrease detrusor contractility