Urological Surgery Flashcards
1
Q
Most common cause of PID
A
STIs - e.g. chlamydia
2
Q
Sequelae of PID
A
- Tubal damage = ectopic pregnancy or infertility
- Chronic pelvic pain
- Recurrent PID
3
Q
Pathological consequences of PID
A
- Salpingitis
- Pyosalpinx
- Hydrosalpinx
- Acute pelvic peritonitis
- Salpingo-oophoritis
- Tubo-ovarian abscess
- Adhesions
4
Q
Causes of chronic PID
A
- Inadequately treated acute disease
- TB
5
Q
Diagnostic size of retention ovarian cyst
A
> 2cm
6
Q
Describe the structure of follicular ovarian cysts
A
- Inner layer of granulosa cells
- Contain clear fluid
- May be multiple
7
Q
Which ovarian cyst is most likely to rupture and cause minor haemorrhage into the peritoneal cavity
A
Luteal cyst
8
Q
Describe psuedomyxoma peritonei
A
Occurs secondary to rupture of benign mucinous cystadenoma which releases tumour cells into the peritoneum that continue to produce mucous
9
Q
Treatment of pseudomyxoma peritonei
A
Peritonectomy (Sugarbaker procedure)
10
Q
Most common malignant ovarian tumour
A
Serous carcinoma (epithelial tumour)
11
Q
Prognosis of ovarian serous carcinoma
A
Poor - 15% 5-year survival
12
Q
Describe Dermoid ovarian cysts
A
- Occur in younger patients
- Contain hair, sebaceous material and teeth
- May undergo torsion
- Malignant transformation is rare
13
Q
What is Meig’s syndrome
A
Ascites and pleural effusions in patients with ovarian fibromas
14
Q
What is a Krukenberg tumour
A
Ovarian malignancy that has metastasised from another site - typically the stomach
15
Q
Complications of fibroadenoma
A
- Cystic degeneration
- Red degeneration (necrosis with haemorrhagic infarction)
- Dystrophic calcification
- Sarcomatous change
16
Q
Risk factors for endometrial carcinoma
A
- Obesity
- HTN
- DM
- Nulliparity
- Long-term Tamoxifen therapy
17
Q
Causes of stress incontinence
A
- Pressure denervation of the. pelvic floor
- External sphincter damage e.g. post-TURP
- Trauma of posterior urethra e.g. pelvic trauma
- Post-menopause
- Obesity
- Constipation
18
Q
Causes of urge incontinence
A
- Idiopathic detrusor instability (irritable bladder)
- Infection
- Loss of cortical control e.g. dementia
19
Q
Causes of continuous incontinence
A
- Females = fistula
- Males = overflow in chronic retention
- Anatomical abnormality e.g. epispadias, ectopic ureter
20
Q
Define secondary nocturnal enuresis
A
Nocturnal enuresis following period of night-time dryness for 6-12 months
21
Q
Investigations for incontinence
A
- Exclude infection/DM
- Bladder diary for 3 days
- Flow cystometry (urodynamic studies) if surgery considered and cause unclear
22
Q
Treatment for stress incontinence
A
- Pelvic floor exercises for 3 months
2. If fails, consider surgery
23
Q
Treatment for urge incontinence
A
- Bladder training for 6 weeks
- If fails, Oxybutynin
- Sacral nerve stimulation
24
Q
Surgical options for stress incontinence
A
- Burch colposuspension
- Needle suspension of the bladder neck (Stamey procedure)
- Pubovaginal slings: Autologous uses rectus fascia, Synthetic with TVT
25
Effect of cerebrovascular disease on the bladder
Detrusor hyper-reflexia - results in frequency and urgency
26
Effect of spinal lesions above the sacral cord
- Fibres passing from sacrum to pons are interrupted
- Results in detrusor sphincter dyssynergia
- Bladder contracts against closed sphincter
- Causes renal damage
27
Symptoms of urinary fistulae
- Recurrent UTI
- Pneumaturia
- Passive incontinence
28
Treatment of small bladder fistula
1. Catheter
| 2. Antibiotics
29
Bacteriuria
Presence of bacteria in the urine
30
Pyuria
Presence of WBC in the urine
31
Sterile pyuria
Pyuria without bacteriuria - warrant evaluation for TB, stones, cancer
32
Define recurrent UTI
More than 3 infections in 1 year
33
Most common bacterial cause of UTI
E. coli
34
Significance of pseudomonas UTI
Likely foreign body
35
Significance of proteus spp UTI
- Hydrolyses urea to form ammonia
- Increases pH of urine
- Predisposes to stone formation
36
Most common cause of epididymo-orchitis in men <35
Chlamydia and gonorrhoea
37
Iatrogenic cause of epididymo-orchitis
Amiodarone
38
Most common cause of epididymitis in older men
Bacterial infection of the urine - usually E. coli and associated with bladder outflow obstruction
39
Symptoms of epididymo-orchitis
- Acute onset of testicular pain and scrotal swelling
- Symptoms of UTI sometimes
- Systemic upset sometimes
40
Investigations in epididymo-orchitis
1. Urinalysis
| 2. USS to R/O abscess
41
Cause of prostatitis
Inflammation secondary to bladder outflow obstruction. In some cases no bacterial cause is found
42
Symptoms of prostatitis
- Fever
- Purulent discharge
- Tender prostate
- Pain on ejaculation
- Haemospermia
43
Investigations for prostatitis
1. Culture - blood and urine
| 2. TRUS - R/O abscess
44
Bacterial cause of Fournier's gangrene
Polymicorbial - E.coli and bacteroides acting in synergy
45
Female cystitis predisposing features
- Short urethra
- Urethral trauma during intercourse
- Pregnancy
46
Pathogenesis of acute pyelonephritis
- Haematogenous spread
- Retrograde ureteric spread
- Organisms include e. coli, proteus, enterobacter, klebsiella, pseudomonas
47
Clinical features of pyelonephritis
- Loin pain/tenderness
- Malaise
- Fever
- Dysuria
- Urgency of micturition
48
Complications of acute pyelonephritis
1. Pyonephrosis - pus in the renal collecting system
| 2. Perinephric abscess - pus around the kidney, may rupture and reach adjacent organs
49
Treatment of pyonephrosis
Percutaneous nephrostomy
50
Treatment of perinephric abscess
Surgical or US-guided drainage
51
Associations of chronic pyelonephritis
- VUR
| - Obstructing lesions during childhood
52
Consequence of chronic pyelonephritis
- Renal scarring
| - Xanthogranulomatous pyelonephritis (granulomatous mass that is difficult to distinguish from renal tumour)
53
Characteristics of interstitial cystitis
- Mucosal ulceration and fissures
- Histological chronic inflammatory change
- Carcinoma must be excluded
54
Difference between congenital and acquired bladder diverticula
- Congenital = full thickness of bladder wall involved
| - Acquired = mucosal outpouching only
55
Antibiotic prophylaxis for transrectal prostate biopsy
Oral ciprofloxacin
56
Antibiotic prophylaxis required prior to endoscopic urological surgery
Gentamicin or cephalosporin
57
Investigations for acute pyelonephritis
1. Urine culture
2. BC
3. Plain X-Ray KUB to RO stones
4. USS to RO obstruction
5. IVU
58
Renal stone recurrence rate
35-75% at 10 years
59
Most common renal stone
Calcium oxalate - 35%
60
Most radiodense renal stone
Calcium phosphate
61
Characteristics of calcium oxalate stones
- Mulberry stones covered in sharp projections
- Occur in alkaline urine
- Cause bleeding
- Often black from blood
62
Characteristics of struvite stones
- Staghorn calculus
- Very alkaline urine
- Smooth and dirty white
- Enlarge rapidly
63
Characteristics of urate stones
- Arise in acidic urine
- Light brown
- Radiolucent
64
Characteristics of cystine stones
- Usually multiple
- Acidic urine
- Metabolic in origin due to reduced cystine reabsorption
- Radio-opaque from sulfur content
65
List the stones occurring in acidic urine
- Urate
| - Cystine
66
List the stones occurring in alkaline urine
- Calcium oxalate (variable)
- Struvite
- Calcium phosphate
67
Stone most likely to be seen in those with inherited recessive condition
Cystine
68
Pathophysiology of struvite stones
- Occur as a result of urease producing bacteria
| - Associated with chronic infections
69
Stones associated with renal tubular acidosis
Calcium phosphate
70
List the stones that are radiolucent
- Urate
| - Xanthine
71
Which stones give a 'ground-glass' radiographic appearance
Cystine
72
Which infections predispose to staghorn (struvite) stones
- Proteus
| - Ureaplasma urealyticum
73
3 most common sites of stone impaction
1. PUJ
2. SIJ
3. VUJ
74
Proportion of patients with renal stones with haematuria
90%
75
Primary investigation for renal stones
Non-contrast CT KUB
76
Supportive treatment in renal colic
1. Rectal Diclofenac
2. Antiemetics
3. Rehydration
4. Alpha-blockers
77
Preferred method of stone management if septic
Percutaneous nephrostomy (retrograde stenting may be performed but carries increased risk of septicaemia)
78
Likelihood of stones <4mm passing naturally
90%
79
Likelihood of stones >6mm passing naturally
5%
80
Management of renal stones <5mm
Conservative - will typically pass within 4 weeks
81
Management of renal stones <10mm
ESWL
82
Management of renal stones 10-20mm
ESWL or ureteroscopy
83
Management of renal stones >20mm (including staghorn calculi)
PCNL
84
Management of ureteric stones <5mm
Watchful waiting
85
Management of ureteric stones 5-10mm
ESWL
86
Management of ureteric stones 10-20mm
Ureteroscopy
87
Management of patients with both renal and ureteric stones
Flexible ureterorenoscopy and laser lithotripsy
88
Mechanism of action of PCNL
Electrohydraulic lithotripsy and ultrasonography
89
Contraindications to ESWL
- Pregnancy
- Aortic aneurysm
- Urosepsis
- Uncorrected coagulopathy
90
In whom with renal stones should nephrectomy be considered
Symptomatic stones and kidney contributing <15% to overall function
91
Management of bladder stones
- Lithoclast fragmentation
| - Open surgery if >5cm
92
Weight of the prostate
20g
93
Lymphatic drainage of the prostate
Internal iliac nodes
94
List the 3 most common causes of upper urinary tract obstruction
1. Stones
2. Malignancy
3. PUJ obstruction
95
Most common causes of lower urinary tract obstruction
- BPH
| - Urethral stricture
96
What investigation confirms renal tract obstruction
MAG-3 scan (shows how well each kidney is draining/functioning)
97
Where does BPH occur
- Transitional zone
| - Nodular hyperplasia of glandular and stromal elements
98
Symptoms of BPH
- Voiding = hesitancy, poor stream, straining, terminal dribbling
- Storage = frequency, urgency, nocturia, incontinence
99
Score to assess severity of prostate symptoms
International prostate symptom score (IPSS)
100
What causes haematuria in BPH
Ruptured bladder neck veins
101
Complications of BPH
- Hypertrophy of bladder muscle
- Hydroureter
- Hydronephrosis
- Pyonephrosis
- Pyelonephritis
102
Uroflowmetery result indicating obstruction
<10ml/s
103
USS post-void volume indicative of chronic retention
>300ml
104
Lifestyle advice for BPH
- Reduce caffeine
| - Reduce fluid intake at night
105
Medical management of BPH and MOA
- Alpha-1 blockers - relax bladder neck and prostatic smooth muscle
- 5-Alpha-Reductase inhibitors - block conversion of testosterone to dihydrotestosterone
106
Surgical management of BPH
1. TURP
| 2. Open retropubic prostatectomy (prostate >90g)
107
Investigating BPH
1. DRE
2. Urinalysis
3. Uroflowmetry
4. Bladder scanning
108
Cause of TURP syndrome
Absorption of large volumes of irrigation fluid through the prostatic venous plexus
109
Expected biochemistry in TURP
- Hyponatraemia
| - Hypervolaemia
110
Symptoms of TURP syndrome
- Visual disturbance (cerebral oedema)
- Nausea
- Vomiting
- Confusion
- Seizures
- Bradycardia
- Hypertension
111
Prevention of TURP syndrome
Minimise operating time to <1 hour
112
Treatment of TURP syndrome
1. Supportive
2. Diuretics
3. Fluid restrict
113
Outline procedure for suprapubic catheter insertion
1. Ensure palpable bladder
2. Prepare lower half of abdomen
3. Inject LA a fingersbreadth above the pubic symphysis
4. Make small skin incision and insert trocar with plastic sheath
5. Introduce 16Fr catheter
114
Contraindications to suprapubic catheter insertion
- Previous abdominal surgery which risk small bowel adhesions
- History of bladder TCC due to risk of seeding
- Bleeding tendency
115
Definition of chronic urinary retention
Residual urinary volume >300ml
116
How does low-pressure chronic retention present
Overlfow incontinence
117
How does high-pressure chronic retention present
Renal failure
118
What causes leg twitching during TURP
Obturator nerve is closely related to the bladder
119
Most common drug-induced cause of haemorrhagic cystitis
Cyclophosphamide
120
Most common cause of weak stream in children
Posterior urethral valves
121
What drug reduces the risk of retention in BPH
Finasteride
122
Renal cell carcinoma colour
Yellow/Brown
123
Macroscopic characteristics of renal cell carcinoma
- Full of fat
- Very vascular
- Circumscribed by pseudocapsule of compressed normal renal tissue
124
Outline the spread of renal cell carcinoma
1. Direct extension:
- Perinephric fat and fascia
- Wall and lumen of renal
vein/IVC
- Adrenal gland
2. Haematogenous Metastasis:
- Cannonball to lung
- Bone
- Brain
125
Risk factors for non-familial renal cell carcinoma
- Acquired renal cystic disease (90% of dialysis patients)
- Smoking
- Lead, cadmium, asbestos, polycarbons
126
Most common histological cell type in renal cell adenocarcinoma
Clear cell adenocarcinoma (>50%)
127
List the potential histology of renal cell adenocarcinoma
- Clear cell
- Papillary
- Chromophobe
128
Classic presenting triad in renal cell carcinoma
1. Pain
2. Mass
3. Haematuria
129
Proportion of renal malignancies made up by renal cell carcinoma
85%
130
Investigating renal cell carcinoma
1. USS
2. CT TAP with contrast
3. Biopsy if ablative therapy planned (not indicated if nephrectomy planned)
131
Management of T1a renal cell carcinoma
Partial nephrectomy (ablasive treatments may be considered in unfit patients)
132
Management of >=T2 renal cell carcinoma
Radical nephrectomy
133
Management of renal TCC
Nephroureterectomy with disconnection of the ureter at the bladder
134
Is adjuvant chemotherapy required in R0 renal cell carcinoma resections
No
135
Potential biochemical results due to paraneoplasia in renal cell carcinoma
- Hypercalcaemia
| - Polycythaemia
136
What is Stauffer syndrome
Liver dysfunction arising due to renal cell carcinoma
137
Prognosis for T1 renal cell carcinoma
90% 5-year survival
138
Presentation of renal sarcoma
- Accounts for 1-2% of renal neoplasms
- Commonly Leiomyosarcoma
- Presents in 5th decade
- Flank pain and weight loss
- Treat with radical nephrectomy
139
Which tumours metastasise to the kidney
- Lung - 20%
- Breast - 12%
- Stomach - 11%
- Lymphoma - rare
140
Associations of angiomyolipoma
- Tuberous sclerosis
- Epilepsy
- Adenoma sebaceum
141
How is diagnosis of angiomyolipoma made
CT - high confidence due to high fat content
142
Management of angiomyolipoma
- <4cm = conservative
- >4cm = enucleation or partial nephrectomy
- Acute bleeding = embolisation or nephrectomy
143
Where do oncocytomas develop from
Intercalated cells of the collecting duct
144
Distribution of urothelial tumours
- 95% bladder
| - 5% upper tract
145
Bladder TCC risk factors
- Smoking
- Occupational - dye, rubber, textile, PVC, beta-naphtaline
- Congenital abnormalities
146
SCC Bladder associations
- Schistosomiasis
| - Indwelling catheters
147
What bones are encountered during posterior approach to the kidney
11th and 12th ribs
148
GOLD standard investigations for bladder cancer
Flexible cystoscopy
149
What 'T' stages remain superficial in bladder cancer
- Ta = non-invasive papillary carcinoma
- Tis = carcinoma in situ
- T1 = tumour invades sub epithelial connective tissue
150
Management of superficial bladder cancer
TURBT
151
Management of recurrent or higher grade superficial bladder cancer
- Mitomycin for 6 weeks
| - BCG for 6 weeks (standard for Grade 3 pT1 tumours)
152
Management of T2-3 non-metastatic bladder cancer
Radical cystectomy with urinary diversion via ileal conduit
153
Management of invasive bladder cancer in those not fit for surgery
Radical radiotherapy
154
Management of metastatic bladder cancer
- Platinum-based chemotherapy
| - Prognosis of 1 year
155
Presentation of bladder cancer
- Painless haematuria
| - Irritative bladder symptoms
156
Where do adenocarcinomas occur in the bladder
At the vault at the site of the urachal remnant and the tumour itself grows outside the bladder
157
Diagnosis of upper tract TCC
IVU is recommended
158
What percentage of those diagnosed with upper tract TCC will have bladder TCC
50%
159
Risk factors for prostate cancer
- Saturated fats, phyto-oestrogens
- Genetics
- African origin
160
Most common histological type of prostate cancer
Adenocarcinoma - 95%
161
Describe the Gleason scoring system
- Histological assessment
- Grades two predominant areas of the tumour
- Gleason 1 = well differentiated
- Gleason 5 = poorly differentiated
- Total score out of 10
162
GOLD standard investigation for the diagnosis of prostate cancer (and its mets)
1. TRUS biopsy + MRI if surgery planned
| 2. Bone scan
163
In whom is watchful waiting used for the management of prostate cancer
- Elderly (life exp <10)
- Multiple comorbidity
- Low Gleason score 3+3
(Require at least 10 biopsies to be taken and ideally a repeat biopsy)
164
Management of localised prostate cancer
- Radical prostatectomy with removal of the obturator nodes
| - OR/ Radical radiotherapy
165
Complications of radical prostatectomy
Erectile dysfunction
166
Complications of prostate radiotherapy
- Radiation proctitis
| - Rectal malignancy
167
How do LHRH agonists work
- Act on pituitary to inhibit LH production
| - Lack of LH means testosterone not produced by Leydig cells of testes
168
Side effects of LHRN agonists
- Lack of energy
- Loss of libido
- Hot flushes
169
How do anti-androgens work
Compete with testosterone at the androgen receptor to block its action
170
Management of hormone-escaped prostate cancer
- Palliative
- Diethylbestrol or prednisolone
- Radiotherapy for bone pain
- Docetaxel
171
Most common genetic abnormality in bladder cancer
Deletion of chromosome 9
172
Risk factors for testicular cancer
- White
- Undescended testes (x10 increase)
- Klinefelter's
- Mumps orchitis
- Family history
- Infertility
173
Most common testicular cancer subtype
Seminoma (50%)
174
Seminoma tumour markers
- AFP = normal
- HCG = elevated in 10%
- LDH = raised in 10-20%
175
Pathological appearance of seminomas
Sheet like lobular pattern of clearcells with substantial fibrous component. Fibrous septa contain lymphocytic inclusions and granulomas may be seen.
176
Investigating testicular cancer
- Scrotal USS
- CXR/CT TAP to exclude chest mets
- Testicular tumour markers
177
Age distribution for seminoma
30-40
178
Management of testicular cancer
1. Orchidectomy via inguinal approach
179
Non-Seminomatous Germ cell tumour markers
- AFP = elevated in 70%
- HCG = elevated in 40%
- Other markers rarely helpful
180
Extratesticular features of Leydig cell tumours
Gynaecomastia
181
Postoperative management of seminomas
- Confined to testes = CT surveillance and single shot carboplatin
- Lymph node mets = radiotherapy with combination chemo if N3/metastatic
182
Postoperative management fo non-seminomatous germ cell tumours
- Confined to testes = close surveillance (20% have retroperitoneal lymph node involvement)
- Metastatic = combination chemo
183
Pathology of penile carcinoma
SCC
184
Risk factors for penile carcinoma
- HPV
| - Unretractable phimosis
185
How should patients with penile cancer and palpable lymph nodes be managed and why
1. If remain palpable after antibiotics
| 2. Bilateral inguinal lymphadenectomy with en-bloc dissection (because the glans drains bilaterally)
186
Describe testicular torsion
Occurs when the spermatic cord and its contents twist within the tunica vaginalis
187
Peak incidence of testicular torsion
- Neonates
| - 12-25 years
188
Anatomical variation predisposing to testicular torsion
Horizontal lie of the testes = bell-clapper deformity (lacks normal attachment to the tunica vaginalis)
189
Presentation of testicular torsion
- Acutely painful hemiscrotum
- Pain radiates to groin/loin
- Vomiting
- Very tender on palpation
- Loss of cremasteric reflex
190
What is the Hydatid of Morgani
Remnant of the Mullerian duct and is a common testicular appendage
191
Difference in presentation between testicular torsion and torsion of the Hydatid Morgani
- Cremasteric reflex is preserved in Hydatid of Morgani torsion
- Less erythematous scrotum
- Normal lie of the testes
- Blue dot in upper half of hemiscrotum
192
Investigating testicular torsion
Clinical diagnosis warrants exploration
193
Outline the treatment of testicular torsion
- Scrotal exploration
- Untwist torsion
- Soak in warm saline for 15 minutes if dusky after torsion
- If doubt over viability then orchidectomy (via scrotal approach)
- If viable, fix both testes via orchiopexy
194
Pathology of hydrocele in children
Patent processus vaginalis (primary hydrocele)
195
Management of hydrocele in children
Inguinal approach to ligate processus
196
Features of hydrocele
- Painless scrotal swelling
- Able to palpate cord above
- Transillumable
- Not separate from testes
197
Investigating hydrocele
- USS in young men to exclude tumour
| - Not necessary in older men
198
Surgical management of hydrocele in adults
Lord Repair - scrotal approach to plicate tunica vaginalis
199
Pathology of epididymal cyst
Fluid-filled scrotal mass arising from congenital diverticula in the epididymal tubes
200
Features of epididymal cyst
- May be multiple
- Usually tense, spherical
- Transilluminable
- Testis can be felt separately
- Lie above and behind testis
- Possible to 'get above lump'
201
How are epididymal cysts distinguished from hydroceles on examination
Epididymal cysts can be felt separately from the testis
202
Management of epididymal cysts
- None if asymptomatic
| - Surgical excision if there is pain (scarring may affect fertility and pain may persist)
203
Pathology of varciocele
Dilatation of the pampiniform plexus that runs within the spermatic cord
204
Which side is varicocele more likely to occur and why
Left side - testicular vein drains into renal vein and is under higher pressure
205
Outline the 3 grades of varicocele
1. Subclinical = detectable on doppler USS
2. Palpable when standing
3. Visible swelling, palpable when lying
206
What must you be wary of in and elderly man presenting with varicocele
May be sign of renal malignancy
207
Management of varicocele
- Ligation of the veins of the groin
| - Embolization
208
Recurrence rate of varicocele
20% - due to collateral circulation or failed venous ligation
209
Pathology of Peyronie's disease
Fibromatosis of unknown aetiology that affects focal areas of the tunica albuginea of the corpus cavernosum
210
Associations of Peyronie's disease
- Dupuytren's contracture
| - Plantar fascial contracture
211
Features of Peyronie's disease
- Penile pain on erection
- Gradual deviation of erection
- Pain resolves after 6-9 months
212
Management of Peyronie's disease
- Conservative for 1 year
- ESWL can be used to soften the penile plaque
- Nesbit operation - plication with excision of the tunica albugenia
213
Management of acute haematocele
Surgical exploration and evacuation of clot
214
Outline the timeline of priapism
- 3-4 hours = pain
- 12 hours = interstitial oedema
- 24-48 hours = necrosis
- >1 week = fibrosis and erectile dysfunction
215
Management of priapism
- Ice packs/cold shower
| - If due to low flow then blood may be aspirated from copora
216
Types of priapism
1. Low flow = due to veno-occlusion and is most painful type requiring emergency treatment if >4 hours
2. High flow = due to unregulated arterial blood flow
217
Causes of recurrent priapism
Typically seen in sickle cell disease, most commonly of the high flow type
218
Medical treatment of erectile dysfunction
1. Phosphodiesterase-5 inhibitors (viagra)
2. Dopamine agonsists
3. Prostaglandin E1 intracorporeal injection
219
When should the foreskin be retractable by
95% by 16
220
Most common cause of true pathological phimosis
Balanitis xerotica obliterans (BXO)
221
Management of pathological phimosis
Circumcision
222
Management of paraphimosis
1. Reduce swelling with ice and squeezing oedematous tissue
2. Attempt reduction
3. Penile or ring block can be used
4. Occasionally necessary to drain oedema with needle
5. Circumcision is recommended
