urogenital radiology Flashcards
how to choose the proper method
- course diagnosis
- patient history and condition
- ALARA (policy that aims to maintain the level of exposure to radiation or other hazardous materials as far below regulatory limits as possible)
- accessibility
- cost/benefit
contrast enhance genitourinary imaging
- CT, DSA:
- non ionic iodinated agents
- iso-osmolar
- renal elimination
- MRI:
- compounds with special magnetic features
- low complication risk
- > becomes high if: allergy, asthma bronchiale, cardiovascular disease, previous severe adverse effect, renal insufficiency, diabetes, dehydration, hemoglobinopathy, hyperproteinemia
what to check before an examination with iodinated contrast material
- history of patient
- hydration
- metformint type antidiabetics
- creatinine level < 130 mmol/L
- GFR > 60 ml/min
- hyperthyreosis
congenital anomalies of the renal parenchyma
- unilateral agenesis
- supernumentary kidney
- horseshoe kidney
- ectopic kidney
- crossed renal ectopy
- renal cysts: polycystic kidney, multicystic kidney
- medullary sponge kidney
congenital anomalies of pelvi-calyeal system
- calyceal diverticulum
- calyx cyst
- congenital hydronephrosis
- pyelon + ureter duplication
- bifid ureter
- megaureter
- ectopic ureter aperture
- ureterocele
- urinary bladder diverticulum
renal tumors: benign
- adenoma
- oncocytoma
- angiomyolipoma
- mesenchymal tumors
- multicystic nephroma
angiomyolipoma: MRI
- T1: hyperintense
- T2: isointense to prerenal fatty tissue
renal tumors: malignant
- hypernephroma
- Wilm’s tumor
- lymphoma
- leukemia
- metastasis
conventional radiography in dagnosis of RCC
- intraveous urography
- sensitivity 67%
- non-specific sign of expansile renal mass
- margins compression
- lack of contrast material filling
- displaced calyces
the role of US in diagnosis of RCC
- B-mode
- Doppler mode
- sensitivity: 79%
- hypo-, iso-, hyper- echoic solid tumor
- central necrosis
- hypervascularisation
- high sensitivity in cases of renal vessel infiltration
MDCT in RCC
- gold standard!
- in unenhanced images, the density is almost the same as the surrounding parenchyma (30-50 HU)
- in arterial phase -> transient hyper-dense blush
- in parenchymal phase -> hypo-dense lesion
Bosniak classification for cysts
I. simple cyst
II. needs follow up
III. malignant in 50%
IV. malignant in 100%
nephrolithiasis/urolithiasis - which modality to use?
low dose CT (best diagnostic method)
chronic prostatitis in US
hypo-echogenicity in the peripheral zone.
small hyper-echoic foci with acoustic shadowing.
coarse intraprostatic calcification.
diagnostic methods in malignant prostate tumors
- transrectal US
- MRI
MRI of prostate cancer (T1 Vs T2)
- multiplanar, T2: assess localisation, size, local invasion.
- T1: assess pelvic bone, lymph node metastases, post-biopsy bleeding
MR-spectroscopy in prostate cancer
changes in metabolite concentrations in prostate cancer, as compared to the normal parenchyma:
- choline is increased (incr. cell proliferation, incr. cell density)
- citrate is decreased (cancer cells oxidise citrate, because of high energy demand).
testis sonography
- high frequency probes (7.5-10 MHz)
- bilateral comparison
- technical parameters set to normal side
- longitudinal section
- transverse sections only for localising the pathology
normal sonogram of testis
- wide variation is size
- most confident parameter in adults in maximal thickness on longitudinal sections (>20 mm).
- head and tail of epididymis -> echogenic structures below the testis
- normal body of epididymis, efferent ductuli, ductus deferens: not discernible.
testicular tumors
- most frequent malignant tumors in males 25-34 y.o.
- 1-2% of all malignant tumors
- risk factors: family history, Caucasians, cryptorchidism
- types: Germ cell tumors, Seminoma, non-seminomas (embryonal cell tumor, teratomas, choriocarcinoma, yolk-sac tumor), stromal tumors (Leydig & Sertoli cell tumors), metastasis, lymphoma, leukemia
seminomas
- most common in 30-40 y.o.
- hyper-echoic, homogenous
- metastasis (lung) present in 25% at time of diagnosis
- AFP is normal
- BHCG is increased
- sensitive to radio-, chemo- therapy
- 10-year survival rate: 75-85%
non-seminomas
- US: mixed echogenicity, due to bleeding, fibrosis, calcification
a) embryonal cell cancer:
- < 2 y.o. or 20-30 y.o.
- very aggressive, early visceral metastasis
b) teratoma:
- benign in boys
- can transform to malignant in adulthood
c) choriocarcinoma:
- 20-30 y.o.
- early metastasis to lung
choriocarcinoma
lymphoma / leukemia
- 7% of all testicular tumors
- > 5 y.o.
- bilateral in 40%
- hypo-echoic areas -> diffuse or local in the lesion
- the entire testis may be involved in leukemia
tumors of female pelvis
& which imaging modalities to use
- benign tumors
- endometrial cc
- cervical cc
- ovarian cc
- use: US, MRI, CT
urinary bladder cancer: MRI
Endorectal & surface coils allow good assessment of the bladder wall (including the base and neck), the prostate and seminal vesicles.
The bladder wall and the lesion can be well differentiated both in T1 and T2 weighted images.
virtual cytoscopy: when to use
In post-operative conditions and injuries.
The goal is to accurately describe the complications.