URINARY SYSTEM DRUGS

Question 1

are limited to the treatment of UTIs. Drug action occurs in the renal tubule and bladder, where it is effective in reducing bacterial growth.

Answer 1

Urinary Antiseptics/Anti-infectives and Antibiotics

Question 2

is an infection of your urinary system. This type of infection can involve your:

1. Urethra (urethritis).
2. Kidneys (pyelonephritis).
3. Bladder (cystitis).

Answer 2

urinary tract infection (UTI)

Question 3

• problem peeing
  -fever
  -chills
  -cloudy foul smelling or
  dark pee
  -pain in abdomen or
  pelvic area, lower back
  -pain while peeing
  -problem during sex

Answer 3

Symptoms of UTI

Question 4

• exerts antimicrobial activity by blocking the reduction of dihydrofolate to tetrahydrofolate, the active form of folic acid, by susceptible organisms. It has inhibitory activity for most gram-positive aerobic cocci and some gram-negative aerobic bacilli.

Answer 4

Trimethoprim and Trimethoprim-Sulfamethoxazole
AKA: Co-Trimoxazole (TMP-SMX)

Question 5

• A drug that stops the growth of bacteria in urine.
• This medication also contains an ingredient that helps to make the urine acidic. When the urine is acidic, methenamine turns into formaldehyde to kill the bacteria.

Answer 5

Methenamine

Question 6

• Absorption: Increase w/ food

- Mechanism of action: Inactivates/ alters bacterial ribosomal proteins: Inhibition of protein synthesis

• bactericidal in urine

Answer 6

Nitrofurantoin

Question 7

• ARE ONE OF THE GROUPS OF URINARY ANTIBACTERIALS THAT ARE EFFECTIVE AGAINST STRAINS OF ACINETOBACTER, CHLAMYDIA, CLOSTRIDIUM, KLEBSIELLA, STAPHYLOCOCCUS, AND STREPTOCOCCUS SPECIES THAT CAUSE LOWER UTIS;

Answer 7

Fluoroquinolones (Quinolones)

CIPROFLOXACIN, OFLOXACIN, AND LEVOFLOXACIN.

Question 8

• If you experience any discomfort, your doctor may prescribe an analgesic, such as ______?, a pain-relief medication for the urinary tract.

Others include those that reduce bladder spasms and over-the-counter pain relievers, such as ________?

Answer 8

Urinary Analgesics
- phenazopyridine
- acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs)

Question 9

• ARE URINARY ANALGESICS THAT ARE USED TO RELIEVE THE URINARY PAIN, BURNING SENSATION, FREQUENCY, AND URGENCY OF URINATION THAT ARE SYMPTOMATIC OF CYSTITIS.
  CAN ALTER THE GLUCOSE URINE TEST; THEREFORE A BLOOD TEST SHOULD BE USED TO MONITOR GLUCOSE LEVELS.

Answer 9

Phenazopyridine

Question 10

• used to treat an overactive bladder
• by relaxing the muscle in your bladder,______? improve your ability to control your urination
• before taking, tell doctor if you have allergies to it
• reduce leaking of urine, feelings of needing to urinate right away, and frequent trips to the bathroom

S/E: - dry mouth, dry eyes, stomach ache, dizziness/ drowsiness

Answer 10

Urinary Antispasmodics
- Tolterodine