Urinary system Flashcards
Kidneys dispose of waste products in urine.
- Nitrogenous waste
- Toxins
- Drugs
- Excess ions
Kidneys regulatory Functions:
-Regulate volume and chemical makeup of blood.
(Water, salts; Acids and bases)
-Production of renin to maintain blood pressure.
-Production of erythropoietin to stimulate red blood production.
-Conversion of vitamin D to its active form.
- Kidneys
- Ureters
- Urinary Bladder
- Urethra
Organs of the Urinary system
urine formation is the result of three processes:
- Glomerular filtration
- Tubular Reabsorption
- Tubular secretion
. Glomerular filtration
- The glomerulus is a filter
- Filtration is a nonselective passive process
- Water and solutes smaller than proteins are forced through glomerular capillary walls into the glomerular capsule.
- Filtration is dependent on blood pressure in the arteries.
- Proteins and blood cells are normally too large to pass through the filtration membrane.
- Once in the glomerular capsule, fluid is called filtrate (basically blood plasma without blood proteins)
- Filtrate leaves via the renal tubule
Tubular reabsorption
The peritubular capillaries reabsorb useful substances from the renal tubule cells, such as:
- Water
- Glucose
- Amino acids
- Ions
- Some reabsorption is passive; but most is active (requires ATP) and very selective.
- There are membrane carriers for substances that need to be reabsorbed; few or none for substances that don’t
- Most reabsorption occurs in the proximal convoluted tubule
Tubular secretion
- Reabsorption in reverse.
- Some materials move from the blood of the peritubular capillaries into the renal tubules to be eliminated in filtrate.
- Hydrogen and potassium ions
- Creatinine
- Secretion is important for:
- Getting rid of substances not already in the filtrate.
- Removing drugs and excess ions
- Maintaining acid-base balance of blood
- Materials left in the renal tubule move toward the ureter
Kidneys have four roles in maintaining blood composition.
.Excreting nitrogen-containing wastes
- Maintaining water balance of the blood
- Maintaining electrolyte balance of the blood
- Ensuring proper blood pH
Urinary Hormone;
Anti-diuretic hormone (ADH)
- Released by posterior pituitary gland if blood volume is too low.
- Travels to kidney’s collecting ducts
- Causes duct cells to reabsorb more water
- Water is returned to the blood
Urinary Hormones;
Aldosterone
- Regulates concentration of sodium ions (Na+) in the extracellular fluid (ECF)
- If there are relatively more Na+ ions in the ECF than in the blood, water leaves the blood and enters the ECF
- The rule is … water follows salt
- Leads to low blood volume and low blood pressure
- Low blood pressure causes cells in the juxtaglomerular (JG) apparatus to release the enzyme renin (not rennin) into the blood
- Renin causes adrenal cortex to release aldosterone
- Aldosterone acts to increase reabsorption of Na+ ions in the DCT and collecting ducts
- As Na+ ions return to blood, water follows
- Blood volume and blood pressure return to normal