Urinary System Flashcards

1
Q

What are the components of the urinary system?

A

Paired kidneys, paired ureters, urinary bladder and urethra

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2
Q

What are medullary rays?

A

Straight tubules in the cortex, some of which are continuous with collecting tubules of the medulla; originate in cortex and project down into the medulla

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3
Q

What kidney cells secrete erythropoietin? Which release renin?

A

Interstitial fibroblasts; juxtaglomerular cells

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4
Q

What is the outer region of the kidney between the capsule and medulla?

A

Cortex

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5
Q

What composes the kidney capsule?

A

Outer layer of collagen and fibroblasts and inner layer of myofibroblasts

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6
Q

What is the area of kidney where vessels enter and exit the kidney

A

Hilum

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7
Q

What part of the kidney contains nephrons?

A

Medullary pyramids

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8
Q

What forms an arch around pyramids and form a border between the outer cortex and medulla?

A

Arcuate vessels

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9
Q

What is the path of urine out of the kidney?

A

Pyramids-> minor calyx -> major calyx-> renal pelvis-> ureter

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10
Q

What structures are located in the cortex portion of the lobules?

A

Glomerulus, proximal convoluted tubule, distal convoluted tubule, part of straight tubules

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11
Q

What are cortical labyrinths?

A

Glomeruli and convoluted tubules located between medullary rays

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12
Q

What is the functional unit of the kidney?

A

Kidney lobule

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13
Q

What is the structure of a kidney lobule?

A

A single medullary ray at the center and half of the adjacent cortical labyrinth on each side

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14
Q

What structures are located within the medulla of the kidney lobule?

A

Ascending and descending limbs of loop of Henle, papillary duct, and renal papilla

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15
Q

What opens into the minor calyx at the renal papilla?

A

Papillary duct of Bellini

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16
Q

What are the two types of nephrons and where can they be found? Which has longer loops of Henle?

A

Juxtamedullary nephrons (close to medulla) and Mid-cortical nephrons (further from medulla); Juxtamedullary nephrons have longer loops of Henle

17
Q

How is the kidney medulla subdivided?

A

Outer medulla (consisting of an outer and inner stripe) and inner medulla

18
Q

What are the components of the nephron?

A

Renal corpuscle, proximal convoluted tubule, proximal straight tubule, descending thin limb, ascending thin limb, macula densa, distal convoluted tubule, connecting tubule, cortical collecting duct, outer medullary collecting duct, inner medullary collecting duct

19
Q

What is the point at which the ascending limb interacts with the renal corpuscle?

A

Macula densa

20
Q

What makes Bowman’s capsule? What is the space in between the layers?

A

Visceral epithelium layer (w/ podocytes) and a parietal cuboidal epithelium; Bowman’s space

21
Q

What is ultrafiltrate?

A

Initially formed urine that is filtered into bowman’s space

22
Q

What are the two sides of the renal corpuscle?

A

The vascular pole and the urinary pole

23
Q

True or False: The basal lamina of the glomerular capillaries is continuous with the basal lamina of the proximal tubule.

A

True

24
Q

What are the projections seen on podocytes?

A

Pedicels

25
Q

What kind of capillaries are glomerular capillaries?

A

Fenestrated

26
Q

What are the components of the glomerulus filtration barrier?

A

Podocyte pedicels, capillary endothelium, and glomerular basement membrane

27
Q

What are the layers of the glomerular basement membrane?

A

Lamina rara externa, lamina densa, lamina rara interna

28
Q

What are the functions of mesangial cells?

A

Mechanical support, control blood flow, control GBM material turnover, secrete vasoactive substances, respond to angiotensin II

29
Q

What membrane specializations are present in the proximal convoluted tubule

A

Microvilli and primary cilia

30
Q

What are plicae?

A

Extensive lateral infoldings on the lateral borders on the cuboidal epithelium that allows the cells to interdigitate

31
Q

Approximately how much filtrate is reabsorbed by the distal tubules?

A

~7%

32
Q

How does the structure of the distal tubule compare to the proximal tubule?

A

There are interdigitations between cells, more basal infoldings, very little and shorter microvilli

33
Q

What cells types are included in the medullary collecting ducts?

A

Intercalated cells and prinicpal cells

34
Q

What is the function of papillary collecting ducts?

A

Osmotic equilibrating devices