Urinary System Flashcards
where are kidneys located?
retroperitoneal
behind abdominal cavity
what do the kidneys do?
filters blood and the filter it forms becomes urine
from what the kidneys filter, what percentage gets reabsorbed?
more than 90%
do females or males get more UTI?
urethra is 5x longer in males
what is urine?
a metabolic waste (break down of proteins and RBC from liver) that your body gets rid of
majority of urine is water
what is the urinary system protected by?
the last 2 ribs
renal cortex
one of the two main regions of the kidney
superficial light region
renal medulla
contains pyramid structures
renal pelvis
made of fibrous connective tissue
renal capsule
made of tough material
will lead into ureter
major calyx
goes into renal capsule
what goes in the calyx?
urine
nephron
the functional unit of the kidney that filters blood and the filtered blood goes into the collecting ducts
where is the last portion of reabsorption done?
the collecting duct
where does the antidiuretic hormone come from?
posterior pituitary
what inhibits antidiuretic hormone?
alcohol
what does caffein cause?
kidney stones because it is diuretic
afferent artery goes?
in
efferent artery goes?
out
glomerulus
is a bed of capillaries located inside bowmen’s capsule
proximal convoluted tubule (PCT)
denotes the part of the tubule attached to the glomerular capsule
lie within the renal cortex
distal convoluted tubule (DCT)
denotes the part of the tubule that is further away
lie within the renal cortex
nephron loop aka loop of henle
connects the proximal and distal convoluted tubules
what are the 3 functions in the nephron?
- blood pressure plays a direct role in the filtration (pressure filtration)
more filtrate leaves capillaries when pressure is higher - tubular filtration
- tubular reabsorption
collecting duct
collects from many nephrons
water follows?
sodium
medication filters in the tubes
macula densa
are cells in the renal corpuscle and ascending limb of loop of henle
they can change size by the amount of salt which makes these cells swell and change the blood pressure
where does most of the filtration occur?
in the cortex
tubular reabsorption
a lot of reabsorption occurs and urine forms
tubular filtration
some filtration
chloride is affected by
sodium
transcellular reabsorption
is directly through the cell needing energy to happen
ascending loop is thicker in order to
make it difficult for ions to go through but water gets through
tubular filtration comes first and then
tubular reabsorption
urine is sterile
until it reaches the outer surface of the skin
fruity urine odor indicates?
ketones
diabetes
3 basic parts of urinanalysis
- physical exam (color, cloudiness, ercipitate, taste, odor, temperature, volume)
2.chemical exam (ph, glucose, ketones, specific gravity, WBC leukocytes, albumin or proteins, blood) - microscopic exam (bacteria, RBC & WBC count, epithelial cells, yeast, E. coli)
what are ketones?
breakdown product from fatty acids and are representative of diabetics. They have FA floating in their blood.
red urine
bleeding
indicates infection like UTI
E. coli is #1 cause of UTI
khaki color green urine
indicates liver dysfunction with breaking down RBC more than should be.
Also from high protein diets which darkens urine
what does high specific gravity mean in urine?
higher than 1.030 means more particles and you are dehydrated
urine volume
problems with urine output can mean a kidney issue
what does albumin in urine mean?
albumin is basically a protein indicative of breakdown of nephron but can also mean infection
equal parts [H+] and [H-] gives?
pH of 7
casts
RBC casts can block nephron not a long term damage tho
hyaline cast
more waxy and a breakdown of nephron
crystals
formation of stones
can be uric acid crystals
or calcium crystals
urinalysis
helps to identify what problem is going on
infection can cause
leakage
how do you test for albumin?
dipstick test
acid tests tests for
blood and ketones
ecotest
bilirubin
what are buffers made of
weak acids or weak bases
helps to maintain pH in blood
pH of blood is
7.35-7.45
bicarbonate is
3rd buffer system
metabolic acidosis
metabolic alkalosis
caused by vomit or dehydration
what is the main component of all body fluids?
water
intracellular fluid ICF
is 2/3 of body’s fluid in cells
extracellular fluid ECF
is 80% interstitial fluid (in lymph, CSF, GI tract fluids, synovial fluids, fluids in eyes) and 20% blood plasma
water moves into areas with
higher salt concentration
diffusions moves from
greater concentration to lower concentration
osmosis
change in osmolarity due to change in [Na+]
edema
fluid. build up in tissues because sodium goes from blood to tissues and retains more water
potassium pill is given to counteract
what regulates urine output
antidiuretic hormone
atrial natriuretic peptide
antidiuretic hormone (ADH) causes
thirst
increase of reabsorption in collecting ducts affecting Na+ levels
ADH secretion shuts off after
intake of water
electrolytes (ions) serve 4 general functions in body
- controls osmosis of water btw body compartments
- maintain acid base balance for normal cellular activity
- carries electrical current
- cofactors needed for optimal enzyme activity
where does Na+ have the highest concentration?
outside of the cell
where are K+ and phosphate highest?
inside the cells
renal failure can be caused by
Na+ retention
Cl-
is the major extracellular ion and controlled by Na+
Potassium(K+) is the
most abundant cation and highest in intracellular fluid
maintains fluid levels
impulse conduction
muscle contraction
found in orange juice, dry fruits
bicarbonate (HCO3-)
prominent ion in plasma
calcium is regulated by the
parathyroid hormone
distilled water
does not have electrolytes and should be neutral
high protein diet causes the blood pH to be
acidic
What are the 3 principal buffer systems of the body fluids?
- protein buffer system (most abundant buffer in ICF and blood plasma)
- carbonic acid-bicarbonate system
- phosphate system
proteins act as both
acidic and basic buffers
once the filtrate enters the calyces it becomes
urine because no further reabsorption can occur
why do kidneys release renin?
to produce aldosterone for when Na+ is deficient in the plasma.
aldosterone
increases the amount of Na+ reabsorption in the kidneys and increases water reabsorption via osmosis
therefore reduces loss of water in urine
antidiuretic hormone (ADH)
is a hormone that increases the amount of water reabsorption in the kidneys
therefore reduces loss of water in urine
atrial natriuretic peptide (ANP)
causes elevated urinary excretion of Na+, accompanied by water.
therefore increases loss of water in urine
natriuresis is excretion of sodium (Na+) in urine
macula densa cells are in
in ascending loop of henle