Urinary endocrinology Flashcards
1
Q
What is the function of ADH?
A
Promotes water resorption in the collecting duct of the kidney by recruitment of AQP2>
2
Q
How is ADH regulated?
A
Recruited in response to:
- Increased extracellular osmolality
- Decreased extracellular volume
3
Q
What is the pathophysiology of cranial diabetes insipidus?
A
Insufficiency of ADH
4
Q
What is the pathophysiology of nephrogenic diabetes insipidus?
A
Insensitivity to ADH
5
Q
What is the mechanism of action of desmopressin?
A
Analog og ADH
- Used to treat cranial DI
- Decreases urine osmolality
6
Q
What is a common cause of SIADH?
A
- Lung cancer
- Heart failure
