Urinalysis procedures Flashcards

1
Q

What are clinical reasons to perform a UA?

A
indicator of health
screening test 
cost effective 
non invasive 
simple to perform
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2
Q

the UA screening test is used to detect and assess what disorders?

A

renal function/disorder
endocrine or metabolic function disorder
urinary tract infection
systemic diseases

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3
Q

What are the two categories of urine colletion?

A

Non instrument collection

instrumented collection

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4
Q

what are the non instrument collections?

A

First morning void
random urine specimen
clean catch
24 hr

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5
Q

what are the instrumented urine collections?

A

urethral catherization
suprapubic needle aspiration
catherization and bladder irrigation

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6
Q

urine specimens are analyzed while fresh, preferably within what time frame?

A

1-2 hours

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7
Q

if unable to test the urine at delivery, what is the timeline for refrigeration?

A

3-6 hours

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8
Q

what happens if urine is left at room temperature

A

it will decompose and deliver inaccurate results. Mostly due to the presence of bacteria.

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9
Q

How is the pH of urine increased while sitting in room temperature?

A

urea splitting bacteria produce ammonia, which then combines with hydrogen ions.

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10
Q

What will contribute to casts that are present (if any) being dissolved?

A

changes in pH

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11
Q

what will bacteria use as a source of energy in urine that is sitting out? resulting in a false negative glycosuria?

A

glucose

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12
Q

what is something you can put in urine to prevent elements such as blood cells and casts from deteriorating?

A

preservatives

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13
Q

which non instrument collection method is the most concentrated, increase number of abnormal elements, decreases their deterioration, and is the recommended specimen for chemical and microscopic examination?

A

First morning void

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14
Q

which non instrument collection is good to be collected anytime, is the most convenient and common, and can detect abnormalities but not as sensitive as “first morning”?

A

random urine

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15
Q

this type of specimen (non instrumented collection) is the specimen of choice for bacterial cultures?

A

cleat catch urines

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16
Q

this type of specimen can have cultures performed 12 hours after collection as long as the specimen is refrigerated?

A

Clean catch urine

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17
Q

this type of specimen gives quantitative results and preservatives may be needed?

A

24 hour collection

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18
Q

this type of collection is used on obese patients, not recommended for bacteriological testing, and should be used only of no other way to collect:

A

urethral catherization

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19
Q

this method of urine collection is the urine collection of choice on infants and young children, performed to confirm positive cultures, and prior to institution of specific therapy:

A

suprapubic needle aspiration

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20
Q

this method of urine collection yields optimum cellular sample of bladder epithelium.

A

catheterization and bladder irrigation

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21
Q

what are the three things involved in urine sample analysis

A

physical
chemical
microscopic

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22
Q

what are the things looked at for PHYSICAL analysis of urine?

A
volume
color
turbidity 
odor 
specific gravity
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23
Q

what is the normal value of urine in a 24 hour period?

A

600-2000 ml

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24
Q

what is the average volume of urine in a 24 hr period?

A

1500 ml

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25
fluid intake, temperature and climate, and amount of perspiration all contribute directly to what?
volume of urine
26
What is the word for urine pigment?
urochrome
27
what is the normal color of urine?
straw color (light yellow) to dark amber
28
urine color may also vary because of what other factors besides hydration?
ingested foods and medications
29
Why would urine be blue green?
methylene blue (used as a dye in diagnostic procedures)
30
why would urine be dark orange?
pyridium (used for UTI infection)
31
what causes urine to be milky white?
chyle
32
phenols, a poisonous compound used for antimicrobial agent, will turn your urine which color?
olive green to brown black
33
the presence of bile will make your urine which color?
yellow to brown (turning greenish with foam when shaken)
34
what color will urine be with the presence of blood?
red or red brown (smoky)
35
what does amorphous phosphate and amorphous carbonate turn your urine?
turbid alkaline
36
what makes your urine turbid alkaline? (pinkish turbidity)
amorphous urates
37
what gives urine it's distinct smell?
volatile acids
38
what gives urine it's ammonia odor after standing for a long time?
breakdown of urea by bacteria
39
what causes urine odor or fruity smell?
ketones
40
pungent smell or Ammonia smell is caused by what?
bacteria
41
what causes maple syrup urine disease?
a congenital metabolic disorder, "maple syrup urine disease"
42
an infant with phenylketonuria will have what smell in his/her urine?
musty or mousy
43
isovaleric acidemia, presence of butyric or hexanoic acid in urine gives what smell?
sweaty feet
44
Specific Gravity of random and 24 hours urine:
Random-1.003-1.035 | 24 Hr- 1.015-1.025
45
the amount of glucose in urine is dependent on what three things?
blood glucose level rate of glomerular filtration degree of tubular reabsorption
46
what is the term for when glucose exceeds the threshold of 160-180mg/dL in the blood?
glucosuria
47
what is ketonuria?
presence of ketones in urine because of incomplete fatty acid utilization
48
starvation, diabetes mellitus, high fat, low carb diets, eclampsia and prolonged vomiting and diarrhea will cause what condition?
ketosis
49
what is the term for presence of blood in the urine?
hematuria
50
What could it indicate if RBC's are present in the urine?
damage/trauma to the kidney or urinary tract renal diseases or menstrual contamination or exercise
51
what types of renal diseases is having RBC's indicative of?
glomerulonephritis malignant hypertension polycystic kidney disease
52
what would bilirubinuria indicate?
hepatocellular disease intra or extra hepatic biliary obstruction (any condition that causes jaundice will result in appearance of bilirubin in urine)
53
is urobilinogen present in urine?
yes, normally in concentrations of 1 EU or less.
54
an increase in urobilinogen is indicative of which diseases?
liver disease or hemolytic disease
55
What is the range for pH and the average in urine?
4.6 to 8.0, but averages 6.0, slightly acidic
56
pathologic conditions that could cause acidic urine:
``` respiratory and metabolic acidosis UTI by E Coli Uremia Severe diarrhea Starvation ```
57
conditions that could cause alkaline urine?
UTI's from proteus and pseudomonas species | respiratory and metabolic alkalosis
58
What in the urine would be a good indicator of renal disease?
protein
59
what are the two mechanisms of proteinuria?
glomerular damage | defect in the reabsorption process of the tubules
60
proteinuria ranges from minimal to significant
minimal <.5 moderate .5-3.5 severe >3.5
61
what is bacteriuria indicative of in your urine?
UTI
62
what is in a indirect test for bacteriuria?
Leukocyte esterase (LE)
63
what is associated with an inflammatory process in or around the urinary tract
leukocyturia
64
what are the strong critical values for glucose?
>1000 mg/dL on urine dipstick with small, medium, or large ketones
65
what is a critical value high urine colony count?
>50,000 colonies/mL if a single organism
66
what amount of protein do we excrete a day?
10-100mg daily
67
ph greater than 7.0 is associated with what?
calcium carbonate calcium phosphate magnesium-ammonium stones
68
ph in urine below what threshold are associated with cystine and uric acid stones?
5.5
69
an increase in urobilinogen may the result of:
hemolytic anemia, cirrhosis or viral hepatitis.
70
if there is an obstruction of the bile duct, what will show up as a dark yellow or greenish brown color?
bilirubin
71
greater than how many RBC's HPF is considered abnormal?
>3
72
RBC's may indicated what in urine?
glomerulonephritis kidney stones cancer infection
73
what can lead to a false positive of blood and hemo in urine and is highly suggestive of rhabdomyolysis?
myoglobin
74
what is defined as significant pyuria?
3> WBC's HPF
75
when glucose reaches what mg/dL in the blood what happens?
180 mg/dL, the ability of the proximal tubule to reabsorb is exceeded and shows up in urine, called glycosuria
76
increased number of epithelial cells may indicated what?
acute tubular necrosis or inflammation