Uric Acid Flashcards
1
Q
Hyperuricaemia
A
May be seen 2dry to either increased cell turnover or decreased renal excretion of uric acid
May be found in asymptomatic patients who have not got gout
May be assoc with Hyperlipidaemia and HTN
May also be seen in conjunction with metabolic syndrome
INCREASED SYNTHESIS
- Lesch-Nyhan disease
- Myeloproliferative disorders
- Diet rich in purines
- Exercise
- Psoriasis
- Cytotoxics
DECREASED EXCRETION
- Drugs: Low dose aspirin, Diuretics, Pyrazinamide
- Pre-Eclampsia
- Alcohol
- Renal Failure
- Lead poisoning
