Upper GI Tract Structure and Function Flashcards

1
Q

How is voluntary chewing controlled?

A

Somatic nerves control skeletal muscles

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2
Q

How is the jaw reflex controlled?

A

Jaw muscles contract and cause the food to press/cause pressure around mouth which is picked up by mechanoreceptors

This inhibits jaw muscles - a safety response

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3
Q

What is in saliva?

A
Water
Alpha-amylase
Mucins
Electrolytes
Lysozyme
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4
Q

What do mucins do?

A

Mucins + water = mucus. Viscous solution with a lubricant function

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5
Q

Why are electrolytes in the saliva?

A

For tonicity/pH regulation

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6
Q

What is lysozymes function?

A

Bacteriocidal - cleaves polysaccharide component of bacterial cell wall

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7
Q

How is salivation controlled?

A

By ANS - PS and S

PS is by cranial nerves 7 and 9

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8
Q

What does PS innervation do?

A

Stimulates a profuse watery secretion

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9
Q

What does S innervation do?

A

Stimulates too - but a small amount of viscous saliva with a high mucus and amylase content

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10
Q

Describe the reflex control of salivation.

A

Presence of food in mouth activates chemoreceptors/pressure receptors in the walls of mouth and tongue

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11
Q

What are the 4 layers of the oesophagus?

A

Mucosa
Submucosa
Muscularis externa
Adventitia

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12
Q

What epithelium is in the mucosa?

A

Stratified squamous non-keratinized

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13
Q

What type of muscle is in the oesophagus muscularis externa ?

A

Upper 1/3 is skeletal

Lower 2/3 is smooth muscle

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14
Q

What are the oesophageal sphincters?

A

Sphincters are the “valves” of the canal and regulate movement in and out of the canal
One at top and bottom
Top one prevent regurgitation

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15
Q

What happens if the top sphincter doesn’t work?

A

Pressure builds in stomach and you projectile vomit

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16
Q

What are the stages of swallowing?

A
Oral 
Pharyngeal
As bolus approaches oesophagus
Once food enters oesophagus 
Oesophageal phase
Bolus nearing stomach
17
Q

Describe the oral phase.

A

Bolus is pushed to back of mouth by tongue

18
Q

Describe the pharyngeal phase.

A

Presence of bolus = reflex contractions of pharyngeal muscles - coordinated by the swallowing centre in medulla

Soft palate reflected backward and upward to close off nasopharynx

19
Q

Describe what happens as the bolus gets near the oesophagus?

A

Upper oseophageal sphincter (UOS) relaxes and epiglottis covers opening to larynx (prevents food entering trachea)

20
Q

Describe what happens when food has enters the oesophagus.

A

UOS contracts to prevent a food reflux

21
Q

What happens in the oesophageal phase?

A

Propulsion of bolus to stomach by peristaltic wave sweeps along entire oesophagus
Propelled to stomach in ~10 secs

22
Q

What happens as bolus nears stomach?

A

LOS releaxes

23
Q

What happens once food is in stomach?

A

Stomach prompted to relax by LOS relaxing and presence of food

Vagus PS innervation also = relaxation of smooth thin elastic muscle - this allows stomach to increase size without stretching

24
Q

What is the stomach max volume without changing pressure?

A

1500 ml

25
Q

How an stomach increase size without stretching?

A

The stomach surface is like curtains, all pleated up when contracted

Pleats called rugae

26
Q

Functions of Stomach

A

Temporary store of ingested material
Dissolve food and start digestion
Control delivery of contents to small intestine
Sterilise ingested material
Produce intrinsic factor (Vitamin B12 absorption)

27
Q

What is the layers of the muscularis externa in the stomach?

A

Inner - oblique
Middle - circular
Outer - longitudinal

28
Q

What is the serosa made from of the stomach?

A

CT outer layer

29
Q

What is on the luminal surface of the stomach?

A

Surface mucus cells
Gastric pits
Gastric glands
Mucus neck, parietal and chief cells