Upper GI tract Flashcards
What are Z lines and T lines?
Label
Label
What is this? Label it.
Label
What is this?
Normal dudodenum
Glandular epithelium with goblet cells (intestinal type epithelium)
Villous architecture
villous:crypt ratio of >2:1
What is this?
Epithelium - full of neurtohips
Acute oesophagitis
What is the commonest cause of oesophagitis
GORD
What are the complications of reflux oesophagitis?
What is Barretts’ oesophagus? What are the 2 types?
What is this?
Columnar lined oesophagus
What is this?
columnar lined oesophagus with intestinal metaplasia
What is this?
Barrett’s oesophagus
What is this sequence?
Metaplasia-dysplasia - cancer pathway
LGD: low grade dysplasia
HGD: high grade dysplasia
ACA: adenocarcinoma
What is adenoma of the oesophagus associated with?
Adenocarcinoma of the oesophagus
What is SCC of the oesophagus associated with?
SCC of oesophagus - make keratin
What is the prognosis of oesophageal carcinoma?
What is this
Oesophageal varices - caused by crirrhosis and portal vein thrombosis
What is gastritis? what are the types?
What are the causes of acute gastritis?
What are the causes of chronic gastritis?
What is this? What causes it? What is the outcome?
What is Helicobacter infection associated with? What is cag-A-positive H.pylori?
What are the other causes of gastritis?
Why should we worry about gastritis?
What is this
Gastric ulcer.
What are the complications of ulcers?
What is this?
- As in the oesophagus:
- intestinal metaplasia in gastric mucosa in response to long term damage
- Increased cancer risk
What is this?
Gastric epithelial dysplasia
Distinction between metaplasia and cancer: no invasion through basement membrane
What is this
Gastric cancer
Bottoms: liver
What are the types of gastric cancers?
What are the other 5% of gastric cancers?
What is this?
What is duodenitis, duodenal ulcer and H.pylori infection?
Most commonly caused by H.pylori
What are the other pathogens causing duodenal ulcers?
Giardia lamblia infection
What is this?
Dots: lymphocytes
What is going on here?
How do we diagnose coeliac disease?
What are patients with coeliac disease more likely to get?
Duodenal MALToma.
T or F
NO
Villous atrophy, increased epithelial lymphocytes
Metabolic disease