Upper GI tract Flashcards

1
Q

What are Z lines and T lines?

A
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2
Q

Label

A
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3
Q

Label

A
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4
Q

What is this? Label it.

A
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5
Q

Label

A
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6
Q

What is this?

A

Normal dudodenum

Glandular epithelium with goblet cells (intestinal type epithelium)
Villous architecture
villous:crypt ratio of >2:1

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7
Q

What is this?

A

Epithelium - full of neurtohips

Acute oesophagitis

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8
Q

What is the commonest cause of oesophagitis

A

GORD

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9
Q

What are the complications of reflux oesophagitis?

A
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10
Q

What is Barretts’ oesophagus? What are the 2 types?

A
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11
Q

What is this?

A

Columnar lined oesophagus

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12
Q

What is this?

A

columnar lined oesophagus with intestinal metaplasia

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13
Q

What is this?

A

Barrett’s oesophagus

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14
Q

What is this sequence?

A

Metaplasia-dysplasia - cancer pathway
LGD: low grade dysplasia
HGD: high grade dysplasia
ACA: adenocarcinoma

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15
Q

What is adenoma of the oesophagus associated with?

A
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16
Q
A

Adenocarcinoma of the oesophagus

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17
Q

What is SCC of the oesophagus associated with?

A
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18
Q
A

SCC of oesophagus - make keratin

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19
Q

What is the prognosis of oesophageal carcinoma?

A
20
Q

What is this

A

Oesophageal varices - caused by crirrhosis and portal vein thrombosis

21
Q

What is gastritis? what are the types?

A
22
Q

What are the causes of acute gastritis?

A
23
Q

What are the causes of chronic gastritis?

A
24
Q

What is this? What causes it? What is the outcome?

A
25
Q

What is Helicobacter infection associated with? What is cag-A-positive H.pylori?

A
26
Q

What are the other causes of gastritis?

A
27
Q

Why should we worry about gastritis?

A
28
Q

What is this

A

Gastric ulcer.

29
Q

What are the complications of ulcers?

A
30
Q

What is this?

A
  • As in the oesophagus:
  • intestinal metaplasia in gastric mucosa in response to long term damage
  • Increased cancer risk
31
Q

What is this?

A

Gastric epithelial dysplasia

Distinction between metaplasia and cancer: no invasion through basement membrane

32
Q

What is this

A

Gastric cancer

Bottoms: liver

33
Q

What are the types of gastric cancers?

A
34
Q

What are the other 5% of gastric cancers?

A
35
Q

What is this?

A
36
Q

What is duodenitis, duodenal ulcer and H.pylori infection?

A

Most commonly caused by H.pylori

37
Q
A
38
Q

What are the other pathogens causing duodenal ulcers?

A
39
Q
A

Giardia lamblia infection

40
Q

What is this?

A

Dots: lymphocytes

41
Q

What is going on here?

A
42
Q

How do we diagnose coeliac disease?

A
43
Q

What are patients with coeliac disease more likely to get?

A
44
Q
A

Duodenal MALToma.

45
Q

T or F

A

NO

46
Q
A

Villous atrophy, increased epithelial lymphocytes

47
Q
A

Metabolic disease