Upper GI Surgery Flashcards
Where does adenocarcinoma and squamous cell carcinoma occur in the oesophagus?
Adenocarcinoma: Distal oesophagus
Squamous cell carcinoma: Proximal and middle third oesophagus
What are the aetiologies of adenocarcinoma?
- Obesity
- Gastro-oesophageal reflux
–Barrett’s metaplasia
–Dysplasia -> Carcinoma
What are the aetiologies for squamous cell carcinoma?
- Smoking
- Alcohol
- Low socio-economic status
What is the presentation of oesophageal cancer?
- Progressive dysphagia
- Anorexia and weight loss
- Odynophagia
- Chest pain/heartburn
- Haematemesis
What are the investigations for oesophageal cancer?
Endoscopy and contrast swallow
Where are the common metastatic sites for the oesphagus?
Liver and lung
What imaging technique is used to determine the T/N stage of osophageal cancer?
EUS
What imaging technique is best for oesphagus mets?
PET CT
What palliative options are available for oesophagus options are availavle for metastatic/unfit?
- Stenting
- Palliative radiotherapy
- Palliative chemotherapy
What are the treatment options for resectable oesophageal carcinoma?
•Oesophagectomy + Chemotherapy
–5 year survival approx 30%
•Concerns about resection/fitness and no metastatic disease
–Chemo/Radiotherapy
–5 year survival approx 20%
What are the possible conduits for oesphagectomy?
Stomach and colon
What are the main risks associated with oespohagectomy?
40% morbidity rate (chest infections, wound infections, heart arrhythmias leaks)
Mortality rate is 5-10%
Return to pre-op quality of life is 10 months
What is the presentation for gastric cancer?
- Nonspecific
- Dyspepsia
- Alarm features
–Dysphagia
–Evidence of GI blood loss
–Weight loss
–Vomiting
–Upper abdominal mass
What are the investigations for gastric cancer?
Endoscopy and contrast meal
What is the staging modality for gastric cancer?
CT Chest / abdomen