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Dm pharm 1 > Untitled Deck > Flashcards

Untitled Deck Flashcards

1
Q

What is the treatment for Tuberculosis (TB)?

A

Rifampin daily x 4 months, or Isoniazid + Rifampin daily x 3 months

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2
Q

What medications are used for Tuberculosis (TB)?

A

Rifampin, Isoniazid, Pyrazinamide, Ethambutol

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3
Q

What are the anticoagulants listed?

A

Warfarin (Coumadin®), Rivaroxaban, Dabigatran, Enoxaparin, Unfractionated heparin, Alteplase

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4
Q

What is the indication for Rifampin?

A

Used for active and latent disease

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5
Q

What are the precautions/ADRs for Rifampin?

A

Can discolor tears an orange color

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6
Q

What is the indication for Isoniazid?

A

Used for active and latent disease

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7
Q

What are the precautions/ADRs for Isoniazid?

A

Administered usually with Vitamin B6 to offset peripheral neurotoxicity and CNS effects

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8
Q

What is the indication for Warfarin (Coumadin®)?

A

Prevents production of vitamin K-dependent coagulation factors

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9
Q

What are the contraindications for Warfarin?

A

Contraindicated in pregnancy, but safe for breastfeeding. Major/fatal bleeding risk.

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10
Q

What is the MOA of Rivaroxaban?

A

Factor Xa inhibitors to prevent clot formation

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11
Q

What are the contraindications for Rivaroxaban?

A

Requires renal dose adjustment. Risk of thrombotic events if discontinued without provider approval.

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12
Q

What is the indication for Dabigatran?

A

Anticoagulant therapy

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13
Q

What are the precautions/ADRs for Dabigatran?

A

Requires renal dose adjustment. Risk of thrombotic events if discontinued without provider approval.

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14
Q

What is the indication for Enoxaparin?

A

Used for VTE, enhances inhibition of clotting proteases

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15
Q

What are the contraindications for Enoxaparin?

A

Can cause heparin-induced thrombocytopenia, anemia, hemorrhage. Renal dose adjustment required.

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16
Q

What is the indication for Unfractionated heparin?

A

Preferred anticoagulant for severe renal failure, patients in need of rapid reversal

17
Q

What is the indication for Alteplase?

A

Thrombolytic therapy

18
Q

What is the MOA of Alteplase?

A

Binds fibrin in a clot, converts plasminogen to plasmin

19
Q

What is the rationale for inhaler devices?

A

Major method of delivery of meds for asthma and COPD. Incorrect use can affect efficacy.

20
Q

What are the types of inhaler devices?

A

pMDI, DPI, SMI

21
Q

What is the purpose of a Spacer/VHC?

A

Allows slower release of medication for proper inhalation

Dm pharm 1 (5 decks)

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