Unit 8 Topic 5: Genetic Mutations

Question 1

A permanent mistake or change made to the original DNA sequence or mRNA transcript

Answer 1

Mutation

Question 2

If a mutation occurs in a gene sequence, it can do what?

Answer 2

Change the protein that is made

Question 3

What disorders are caused by a mutation in a singular gene.

Answer 3

• Cystic Fibrosis
• Sickle cell Anemia
• Tay-Sachs Disease
• Color blindness

Question 4

Point Mutation (pm)

Answer 4

One nitrogenous base is changed

Question 5

What are the different types of mutations?

Answer 5

Point mutation, Silent, Missense, Nonsense, Frameshift (insertion or deletion)

Question 6

Silent Mutation

Answer 6

PM, no change in outcome because it codes for the same amino acid

Question 7

Missense

Answer 7

PM, codes for a different amino acid

Question 8

Nonsense

Answer 8

PM, creates a stop codon and the rest of code is not read.

Question 9

Frameshift (insertion)

Answer 9

Base added to the sequence, shifts reading frame over.

Question 10

Frameshift Deletion

Answer 10

Base removed from the sequence, shifts reading frame over.