Unit 8: Complications of Adolescents Flashcards
This are infections or infectious disease syndromes transmitted primarily by sexual contact?
Sexually transmitted infections (STIs)
It is considered as primary prevention. It is the most effective way of reducing adverse consequences of STIs for adolescents.
Preventing Infection
It is the secondary prevention which can prevent personal complications and transmission to others.
Prompt diagnosis and treatment of current infections
These are immunologic deficiency disorders that are considered as syndromes wherein the body is unable to mount an immune response?
AIDS, SCID and Wiskott-Aldrich Syndrome
The immune response can also be misdirected. In autoimmune disorders, ______, ______ and ______ attack healthy cells.
antibodies, macrophages and lymphocytes
True or False.
Research has led to early diagnosis and improved medical treatments for HIV infection, changing this disease from a rapidly fatal one to a chronic disease.
TRUE
This happens when virus invade the immune system.
HIV
AIDS. Diagnosed when ______ cell count is less than _____ or when the patient has an _______ (e.g. serious infection, cancer).
CD4 T, 200, AIDS-defining complication
The first AIDS cases in the pediatric population in the United States were identified in?
children born to HIV-infected mothers and in children who received blood products
More than _____ % of these children acquired the disease perinatally from their mothers.
90
HIV is a _______ that is transmitted by _______ and ______.
retrovirus, lymphocytes and monocytes
This uses RNA as their genetic material. The cell converts this RNA into DNA, which is then inserted into the DNA of the host cells. This leads to the production of more of it that would infect other cells.
Retroviruses
Retroviruses can be found in the?
blood, semen , vaginal secretions and breast milk
What is the incubation or latency period of retroviruses?
months to years
This type of transmission of HIV occurs through intimate sexual contact.
Horizontal transmission
This type of transmission occurs when HIV infected pregnant women pass it to her infant.
Parenteral or vertical transmission
The count eventually reaches a critical level which there is a substantial risk for _____, followed by ______.
opportunistic illness, death
What are the common defining conditions for _______?
- __________ carinii pneumonia (PCP)
- __________ interstitial pneumonitis (LIP)
- recurrent ________ infections
- _________ syndrome
- _________ esophagitis
- HIV _________
- _________ disease
- Mycobacterium __________ complex infection
- Pulmonary _________
- Herpes _________ disease
- AIDS
- Pneumocystis
- Lymphoid
- bacterial
- wasting
- Candidal
- Encephalopathy
- Cytomegalovirus
- avium-intracellular
- candidiasis
- simplex
What are the common manifestation of immunodeficiency virus infection in Children?
- Lymphadenopathy
- Hepatosplenomegaly
- Oral Candidiasis
- Chronic or recurrent diarrhea
- failure to thrive
- developmental delay
- Parotitis
What are the common or defining conditions for acquired immune deficiency syndrome in children?
- Pneumocystis Carinii Pneumonia
- Lymphoid interstitial Pneumonitis
- Recurrent bacterial infection
- Wasting Syndrome
- Candidal Esophagitis
- HIV encephalopathy
- Cytomegalovirus Disease
- Mycobacterium avium-intracellular complex infection
- Pulmonary Candidiasis
- Herpes Simplex Disease
For children 18 months of age and older the HIV ______ and ______ are performed to determine HIV infections in infants born to HIV infected mothers.
enzyme-linked immunosorbent assay and Western Blot immunoassay
Most commonly the _____ is used for detection of Proviral DNA.
Polymerase Chain Reaction
A controlled-center study tested _______ as a novel technology that is ideal for early infant diagnosis of HIV-1.
Recombinase Polymerase Amplification.
Recombinase Polymerase Amplification has two main functions which are?
- Combination tests that detect both HIV antigen and antibody
- Tests that accurately differentiate HIV-1 from HIV-2 antibodies
What are the immunological category in pediatric human immunodeficiency virus infection classification?
- No evidence of suppression
- evidence of moderate suppression
- severe suppression
N1, N2, N3
No signs and symptoms
A1, A2, A3
Mild signs or symptoms
B1, B2, B3
Moderate Signs or Symptoms
C1, C2, C3
Severe Signs or Symptoms
Children whose human immunodeficiency virus (HIV) infection status is not confirmed is classified as?
E (for prenatally exposed)
What are the classes of antiretroviral agents?
- nucleoside reverse transcriptase inhibitors
- non nucleoside reverse transcriptase inhibitors
- Protease inhibitors
This are used to stall the emergence of drug resistance?
Combinations of antiretroviral drugs
What are the laboratory markers which are used to assist in monitoring both the disease progression and response to it?
CD4 + lymphocyte count, viral load
Is often employed for other opportunistic infections such as disseminated mycobacterium avium-intracellular complex, candidiasis, or herpes simplex.
Prophylaxis
This has been helpful in preventing recurrent or serious bacterial infections in some HIV infected children?
IV Gamma Globulin (IVGG)
It is recommended for children exposed to and infected with HIV.
Immunization against common childhood influenza, including pneumococcal and influenza vaccines
These have changed HIV disease from a rapidly fatal illness to a chronic disease.
Early recognition and improved medical care
They are the fastest growing groups of newly infected persons in the us.
young adults (13-24)
It is defined as an increase in body weight resulting from an excessive accumulation of body fat relative to lean body mass.
Obesity
It refers to the state of weighing more than average for height and body build.
Overweight