Unit 7 Endocrine pt. 2 ppt. slides

Question 1

An autoimmune disorder that results in destruction of the beta cells of the pancreatic islets, resulting in a deficiency of insulin:

Answer 1

Type 1 diabetes mellitus

Question 2

Insulin dependent diabetes is known as which type:

Answer 2

Type 1 diabetes mellitus

Question 3

Inadequate beta-cell response to the progressive insulin resistance that typically accompanies advancing age, inactivity and weight gain is:

Answer 3

Type 2 diabetes mellitus

Question 4

Oral antimicrobials like azole antifungals inhibit CYP2C9. Many anti diabetic drugs are metabolized by the CYP2C9 family which places the patient at a risk for

Answer 4

hypoglycemia. Educate patient to report and be aware of risk of hypoglycemia and oral antimicrobials.

Question 5

The calcium channel blockers to avoid with the metabolism of CYP3A4 family and anti diabetic drugs are:

Answer 5

Diltiazem
Verapamil
(educate alternative calcium channel blocker)

Question 6

Treatment steps for diabetes

Answer 6

1. nonpharmacological: establish goals
2. Diet, Exercise, nutrition counseling
3. Metformin

Question 7

Diabetic women who intend to become pregnant should take what type of diabetes medication?

Answer 7

switch to insulin

Question 8

Which diabetic agents are not recommended in pediatrics?

Answer 8

Sulfonylureas, meglitinides, a-glucosidase inhibitors