UNIT 6 -- “Nuts and Bolts” Flashcards

1
Q

Four uses of gas in a process manufacturing plant.

A

__operating automatic control valves________________________________

  1. _______transferring process materials____________________________________
  2. _______blanketing process liquids_______________________________________
  3. _______supporting cell growth_____
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2
Q

Five features of sanitary piping.

A

stainless steel construction_________________________________________

  1. ______no dead leg______________________________________________________
  2. _______air tight fittings/coupling___________________________________________
  3. ______sloped piping_____________________________________________________
  4. _____no 90° bends_____
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3
Q

LIST 2 EXAMPLES OF EACH:
batch process
continuous process

A
  1. batch process ____laundry_______________ and ______baking a cake________
  2. continuous process ____hot water heating__ and _______car engine_________
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4
Q

product

A

output

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5
Q

plant utilities

A

input

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6
Q

raw materials

A

input

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7
Q

process stream

A

output

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8
Q

waste

A

output

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9
Q

labor

A

input

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10
Q

seal

A

joins metal parts to prevent leakage of fluids

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11
Q

pump

A

propels fluid movement

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12
Q

. tank

A

stores and mixes fluids

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13
Q

piping

A

carries fluid from one location to another

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14
Q

valve

A

directs fluid flow

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15
Q

uses gas to exert pressure

A

PNEUMATICS

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16
Q

compressible medium

A

PNEUMATICS

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17
Q

. used to multiply force

A

HYDRAULICS

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18
Q

non-compressible medium

A

HYDRAULICS

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19
Q

. uses liquid to exert pressure

A

HYDRAULICS

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20
Q

. U.S. Pharmacopeia (USP)

A

high purified but not guaranteed pyrogen-free

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21
Q

raw water

A

plant input

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22
Q

. DI water

A

metals and salts removed

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23
Q

Water for Injection (WFI)

A

most highly purified, free of pyrogens

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24
Q

reverse osmosis

A

water passes through, but not larger molecules

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25
Q

irradiation

A

kills microorganisms

26
Q

distillation

A

removes almost all ions, microorganisms, and large organic

molecules including pyrogens

27
Q

sterile filtration

A

. removes microorganisms with filters that have a pore size of 0.2
microns

28
Q

changes from vapor to liquid

A

CONDENSATION

29
Q

releases heat to surroundings

A

CONDENSATION

30
Q

. caused by low temperature and

high pressure

A

CONDENSATION

31
Q

changes from liquid to vapor

A

EVAPORATION

32
Q

caused by high temperature and

low pressure

A

EVAPORATION

33
Q

absorbs heat from surroundings

A

EVAPORATION

34
Q

scrubber

A

removes toxic gas pollutants

35
Q

growth medium

A

mixture of raw materials used to grow cells during fermentation process

36
Q

hazardous waste

A

must be treated before being released into the environment

37
Q

CIP

A

method of cleaning large equipment that can not be moved to a cleaning area or
put into a washing machine or cleaning tank.

38
Q

material compatibility

A

items, such as tanks and piping, should not interact with fluids in them

39
Q

liquid nitrogen

A

used to store frozen cell cultures

40
Q

stripping

A

separates liquids in a simple mixture, using differences in their boiling points

41
Q

The upstream side of a filter is the _____ side and contains the _____.

A

high pressure, retentate

42
Q

The downstream side of a filter is the _____side where the _____ appears.

A

low pressure, filtrate

43
Q

The difference between microfilters and ultra filters are the size of the holes used to
separate _____.

A

small particles

44
Q

. In _____, the filter cake must be removed to prevent _____.

A

dead-end flow, clogging

45
Q

___are separated using a drum filter.

A

large particles

46
Q

In _____ the process stream flows across the surface of the filter.

A

tangential flow

47
Q

cavitation

A

is the formation of gas pockets in a flowing liquid

48
Q

centrifugation

A

uses centrifugal force to separate different components in a mixture by _

_____________forcing the heavier component to the outside

49
Q

. pressure head (suction head)

A

is the total pressure on the suction side of the pump___

50
Q

discharge pressure _

A

is the total pressure on the discharge side of the pump

51
Q

EXPLAIN THE DIFFERENCE BETWEEN POSITIVE DISPLACEMENT AND

CENTRIFUGAL PUMPS.

A

Centrifugal pumps use centrifugal force to move fluid. Positive displacement_______

______pumps move fluid by picking it up in specific amounts and moving it forward.

52
Q

IDENTIFY TWO TYPES OF POSITIVE DISPLACEMENT PUMPS AND GIVE AN
EXAMPLE OF EACH.

A

rotary pump = lobe pump reciprocating pump = diaphragm pump___

53
Q

ball valve

A

flow control element has a hole that

rotates and is round primary uses = on-off

54
Q

diaphragm valve

A

flow control element is a plunger that
moves up and down and presses against a
flexible surface primary use = throttling

55
Q

check valve

A

flow control element has a hole that

rotates and is round primary = special purpose

56
Q

globe valve

A

flow control element is a disc raised and
lowered with a handwheel; fluid flow
causes turbulence primary= throttling

57
Q

butterfly valve

A

flow control element is a rotating disc

primary = on-off

58
Q

gate valve

A

flow control element raises and lowers
and is wedge-shaped
primary= on-off

59
Q

plug valve

A

low control element has a hole that
rotates and is wedge-shaped
primary = on-off

60
Q

relief valve

A

flow control elements opens at preset

pressure primary= special purpose

61
Q

___ chromatography

A

Unit operation in many chemical and bioprocessing operations that is used to separate the
product from impurities, and/or concentrate the product.