UNIT 6 -- “Nuts and Bolts” Flashcards
1
Q
Four uses of gas in a process manufacturing plant.
A
__operating automatic control valves________________________________
- _______transferring process materials____________________________________
- _______blanketing process liquids_______________________________________
- _______supporting cell growth_____
2
Q
Five features of sanitary piping.
A
stainless steel construction_________________________________________
- ______no dead leg______________________________________________________
- _______air tight fittings/coupling___________________________________________
- ______sloped piping_____________________________________________________
- _____no 90° bends_____
3
Q
LIST 2 EXAMPLES OF EACH:
batch process
continuous process
A
- batch process ____laundry_______________ and ______baking a cake________
- continuous process ____hot water heating__ and _______car engine_________
4
Q
product
A
output
5
Q
plant utilities
A
input
6
Q
raw materials
A
input
7
Q
process stream
A
output
8
Q
waste
A
output
9
Q
labor
A
input
10
Q
seal
A
joins metal parts to prevent leakage of fluids
11
Q
pump
A
propels fluid movement
12
Q
. tank
A
stores and mixes fluids
13
Q
piping
A
carries fluid from one location to another
14
Q
valve
A
directs fluid flow
15
Q
uses gas to exert pressure
A
PNEUMATICS
16
Q
compressible medium
A
PNEUMATICS
17
Q
. used to multiply force
A
HYDRAULICS
18
Q
non-compressible medium
A
HYDRAULICS
19
Q
. uses liquid to exert pressure
A
HYDRAULICS
20
Q
. U.S. Pharmacopeia (USP)
A
high purified but not guaranteed pyrogen-free
21
Q
raw water
A
plant input
22
Q
. DI water
A
metals and salts removed
23
Q
Water for Injection (WFI)
A
most highly purified, free of pyrogens
24
Q
reverse osmosis
A
water passes through, but not larger molecules
25
irradiation
kills microorganisms
26
distillation
removes almost all ions, microorganisms, and large organic
| molecules including pyrogens
27
sterile filtration
. removes microorganisms with filters that have a pore size of 0.2
microns
28
changes from vapor to liquid
CONDENSATION
29
releases heat to surroundings
CONDENSATION
30
. caused by low temperature and
| high pressure
CONDENSATION
31
changes from liquid to vapor
EVAPORATION
32
caused by high temperature and
| low pressure
EVAPORATION
33
absorbs heat from surroundings
EVAPORATION
34
scrubber
removes toxic gas pollutants
35
growth medium
mixture of raw materials used to grow cells during fermentation process
36
hazardous waste
must be treated before being released into the environment
37
CIP
method of cleaning large equipment that can not be moved to a cleaning area or
put into a washing machine or cleaning tank.
38
material compatibility
items, such as tanks and piping, should not interact with fluids in them
39
liquid nitrogen
used to store frozen cell cultures
40
stripping
separates liquids in a simple mixture, using differences in their boiling points
41
The upstream side of a filter is the _____ side and contains the _____.
high pressure, retentate
42
The downstream side of a filter is the _____side where the _____ appears.
low pressure, filtrate
43
The difference between microfilters and ultra filters are the size of the holes used to
separate _____.
small particles
44
. In _____, the filter cake must be removed to prevent _____.
dead-end flow, clogging
45
___are separated using a drum filter.
large particles
46
In _____ the process stream flows across the surface of the filter.
tangential flow
47
cavitation
is the formation of gas pockets in a flowing liquid
48
centrifugation
uses centrifugal force to separate different components in a mixture by _
_____________forcing the heavier component to the outside
49
. pressure head (suction head)
is the total pressure on the suction side of the pump___
50
discharge pressure _
is the total pressure on the discharge side of the pump
51
EXPLAIN THE DIFFERENCE BETWEEN POSITIVE DISPLACEMENT AND
| CENTRIFUGAL PUMPS.
Centrifugal pumps use centrifugal force to move fluid. Positive displacement_______
______pumps move fluid by picking it up in specific amounts and moving it forward.
52
IDENTIFY TWO TYPES OF POSITIVE DISPLACEMENT PUMPS AND GIVE AN
EXAMPLE OF EACH.
rotary pump = lobe pump reciprocating pump = diaphragm pump___
53
ball valve
flow control element has a hole that
| rotates and is round primary uses = on-off
54
diaphragm valve
flow control element is a plunger that
moves up and down and presses against a
flexible surface primary use = throttling
55
check valve
flow control element has a hole that
| rotates and is round primary = special purpose
56
globe valve
flow control element is a disc raised and
lowered with a handwheel; fluid flow
causes turbulence primary= throttling
57
butterfly valve
flow control element is a rotating disc
| primary = on-off
58
gate valve
flow control element raises and lowers
and is wedge-shaped
primary= on-off
59
plug valve
low control element has a hole that
rotates and is wedge-shaped
primary = on-off
60
relief valve
flow control elements opens at preset
| pressure primary= special purpose
61
___ chromatography
Unit operation in many chemical and bioprocessing operations that is used to separate the
product from impurities, and/or concentrate the product.
