Unit 5: Chapter 22 (Karch 7th Ed) - Psychotherapeutic Agents Flashcards

1
Q
  1. A group of patients are being screened to see which patients would be the best candidate for a
    psychotherapeutic drug trial that helps people concentrate longer on activities. Which patient would be
    best suited for this trial?
    A) A 28-year-old salesperson who alternates between overactivity and periods of depression
    B) A 32-year-old hyperactive nursing student who cannot focus long enough to take a test
    C) A 55-year-old physician who suddenly falls asleep during the day without warning
    D) A 16-year-old youth who say he can make the light turn on by pointing at it and hears voices
A

Ans: B
Feedback:
Attention-deficit disorders involve various conditions characterized by an inability to concentrate on
one activity for longer than a few minutes. The nursing student needing accommodations has an
attention-deficit disorder. The salesperson exhibits signs of mania, which are characterized by periods
of extreme overactivity and excitement followed by extreme depression. The physician is experiencing
narcolepsy, which is defined as daytime sleepiness and sudden periods of loss of wakefulness. The
teenager is schizophrenic and is exhibiting paranoia, hallucinations, and delusions

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2
Q
  1. What nursing intervention is appropriate for a 70-year-old female patient receiving lithium?
    A) Instruct the patient to use barrier contraceptives.
    B) Monitor blood glucose levels.
    C) Monitor fluid and sodium intake.
    D) Encourage the patient to check daily for weight loss.
A

Ans: C
Feedback:
Older patients, and especially those with renal impairment, should be encouraged to maintain adequate
hydration and salt intake. Decreased dosages may also be necessary with the elderly. A 70-year-old
patient would not be concerned about the use of contraceptives. These drugs alone do not affect glucose
levels. Weight loss is usually not associated with lithium use.

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3
Q
  1. A nurse is caring for a patient who is taking lithium for mania. The nurse’s assessment includes a
    notation of a lithium serum level of 2.4 mEq/L. The nurse anticipates seeing what?
    A) Fine tremors of both hands
    B) Slurred speech
    C) Clonic movements
    D) Nausea and vomiting
A

Ans: C
Feedback:
Serum levels of 2 to 2.5 mEq/L may produce ataxia, clonic movements, possible seizures, and
hypotension. Fine hand tremors, slurred speech, and nausea and vomiting are indicative of lithium
levels less than 1.5 mEq/L.

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4
Q
  1. The nurse administers chlorpromazine intramuscularly to the preoperative patient who is extremely
    anxious about surgery in the morning. What priority teaching point will the nurse provide this patient?
    A) Remain recumbent for at least 30 minutes after the injection.
    B) Do not eat for 1 hour after the drug is administered.
    C) Encourage fluids with the goal of 3,000 mL/d.
    D) Avoid eating avocados and oranges when taking this medication.
A

Ans: A
Feedback:
When giving a parenteral form of an antipsychotic, the patient should remain recumbent to decrease the
risk of injury if orthostatic hypotension occurs. Eating after drug injection should not interfere with the
drug’s absorption and although adequate hydration should be maintained there is no need to increase
fluid intake. Avocados and oranges are not contraindicated in patients receiving this medication

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5
Q
  1. The nurse is presenting an in-service at a children’s unit on hyperactivity. The nurse is told that a 6-
    year-old on the unit is being treated with methylphenidate (Ritalin). The presenting nurse talks about
    discharge teaching for this patient and the importance of monitoring what?
    A) Long bone growth
    B) Visual acuity
    C) Weight and complete blood count
    D) Urea and nitrogen levels
A

Ans: C
Feedback:
Methylphenidate is associated with weight loss, bone marrow suppression, and cardiac arrhythmias.
Weight, blood count, and cardiac function should be monitored regularly. The drug is not associated
with renal dysfunction, visual changes, or growth retardation, so those values would not need to be
regularly evaluated as part of drug therapy.

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6
Q
6. The nurse is caring for a patient taking an oral neuroleptic medication. What is the nurse’s priority
assessment to monitor for?
A) Urge incontinence
B) Orthostatic hypotension
C) Bradycardia
D) Tardive dyskinesia
A

Ans: D
Feedback:
The nurse would monitor for and teach the patient and family about tardive dyskinesias because it is
such a common adverse effect with continued use of the drug. Oral neuroleptic agents do not cause
urge incontinence, orthostatic hypotension, or bradycardia.

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7
Q
  1. A psychotic patient is admitted through the emergency department. The physician has ordered
    chlorpromazine (Thorazine) 25 mg intramuscularly. After administration of the medication, what is the
    nurse’s priority to evaluate?
    A) The patient’s ability to ambulate
    B) Return of the patient’s appetite
    C) A decrease in psychotic symptoms
    D) Blood pressure and pulse
A

Ans: C
Feedback:
The nurse will evaluate the effectiveness of the drug in diminishing psychotic symptoms because this is
the purpose of administering the drug. Monitoring blood pressure, pulse, and appetite is part of all
patient care but is not the priority evaluation criterion for this patient. The ability to ambulate and
maintain adequate nutrition would be assessed but is not the priority evaluation for this patient.

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8
Q
  1. A patient diagnosed with bipolar disorder is to be discharged home in 48 hours. The nurse has
    completed patient teaching regarding the use of lithium. What statement by the patient indicates an
    understanding of their responsibility?
    A) I will increase my salt intake.
    B) I will increase my fluid intake.
    C) I will decrease my salt intake.
    D) I will decrease my fluid intake
A

Ans: B
Feedback:
To maintain a therapeutic lithium level, the patient must increase fluids. A decrease in consumption of
fluids can lead to toxicity. An increase in salt intake can lead to lithium excretion and a decrease in
effectiveness. A decrease in salt intake can cause retention, also leading to toxicity. Adequate salt
intake is necessary to keep serum levels in therapeutic range but need not be increased or decreased.

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9
Q
  1. A patient has just been prescribed a phenothiazine. During patient teaching about this drug, what would
    be important for the nurse to tell the patient?
    A) The urine can turn pink or reddish.
    B) The urine output will be decreased.
    C) Diarrhea can be an adverse effect.
    D) Hyperexcitability can occur
A

Ans: A
Feedback: Phenothiazines can cause the urine to turn pink or reddish. The patient should be informed that this is a
simple color change and is not caused by blood in his urine. Decreased urine output is not associated
with this drug. Constipation is usually an adverse effect of the drug. Drowsiness, not hyperexcitability,
can occur.

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10
Q
  1. A patient, in the manic phase of bipolar disorder, is being discharged home on an antimanic drug. What
    antimanic drug is used for long-term maintenance of bipolar disorders?
    A) Aripiprazole (Abilify)
    B) Lamotrigine (Lamictal)
    C) Quetiapine (Seroquel)
    D) Ziprasidone (Geodon)
A

Ans: B
Feedback:
Lamotrigine is used for long-term maintenance of bipolar disorders. Aripiprazole and ziprasidone are
used for acute manic and mixed episodes of bipolar disorders. Quetiapine is used as adjunct or
monotherapy for the treatment of manic episodes associated with bipolar disorder.

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11
Q
  1. A 16-year-old youth has just been diagnosed with schizophrenia. The parents ask the nurse what causes
    schizophrenia. What would be the nurse’s best response?
    A) Schizophrenia is caused by pain that the brain perceives.
    B) Schizophrenia is thought to occur due to trauma experienced in childhood.
    C) Schizophrenia is thought to reflect a fundamental biochemical abnormality.
    D) Schizophrenia is caused by seizure activity in the brain.
A

Ans: C
Feedback:
This disorder, which seems to have a very strong genetic association, may reflect a fundamental
biochemical abnormality. Mental disorders are now thought to be caused by some inherent dysfunction
within the brain that leads to abnormal thought processes and responses. Schizophrenia is not caused by
pain, childhood trauma, or seizure activity.

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12
Q
  1. A patient on chlorpromazine is feeling better and decides they no longer need their medication. The
    nurse teaches the patient that abrupt withdrawal of a typical antipsychotic medication can result in what?
    A) Insomnia
    B) Tardive dyskinesia
    C) Somnolence
    D) Constipation
A

Ans: A
Feedback:
Sudden withdrawal can cause cholinergic effects such as diarrhea, gastritis, nausea, vomiting,
dizziness, arrhythmias, drooling, and insomnia. Abrupt withdrawal of a typical antipsychotic generally
does not cause tardive dyskinesia, somnolence, or constipation.

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13
Q
13. A patient’s medication has been changed to clozapine (Clozaril). The nurse evaluates this patient for
which life-threatening adverse effect?
A) Renal insufficiency
B) Emphysema
C) Neuroleptic malignant syndrome
D) Cerebrovascular accident (CVA)
A

Ans: C
Feedback:
Neuroleptic malignant syndrome can be a life-threatening adverse effect of atypical nonphenothiazines.
Renal insufficiency, emphysema, and CVA are not commonly seen adverse effects of
atypical non-phenothiazines.

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14
Q
  1. The nurse is caring for an adolescent patient who began taking an antipsychotic drug last month to treat
    newly diagnosed schizophrenia. The drug has not been effective and the mother asks the nurse if this
    means the adolescent’s symptoms cannot be controlled by drugs. What is the nurse’s best response?
    A) Patients commonly have to try different drugs until the most effective drug is identified.
    B) Some patients do not respond to drugs and have to rely solely on behavior therapy.
    C) Most likely your child was not taking the medication properly as prescribed.
    D) He may need to take multiple drugs before effects will be seen that control his symptoms.
A

Ans: A
Feedback:
A patient who does not respond to one drug may react successfully to another agent. Responses may
also vary because of cultural issues. The selection of a specific drug depends on the desired potency
and patient tolerance of the associated adverse effects. It is not common to have a patient who does not
demonstrate some improvement from medications so it would be incorrect to tell the mother the child
won’t respond to any drug after trying only one medication. There is no indication the drug was taken
improperly and even properly administered drugs will not work on all patients. Multiple drug therapy is
not indicated by the question

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15
Q
15. Haloperidol is a typical antipsychotic drug. What adverse effect is associated with this drug?
A) Bradycardia
B) Bradypnea
C) Extrapyramidal effects
D) Hypoglycemia
A

Ans: C
Feedback:
Haloperidol produces a relatively low incidence of hypotension and sedation and a high incidence of
extrapyramidal effects. Haloperidol does not generally produce bradycardia, bradypnea, or
hypoglycemia.

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16
Q
  1. The pharmacology instructor is explaining to their class the difference between the typical and the
    atypical groups of antipsychotic drugs. What medication would the instructor explain to the students
    has fewer extrapyramidal effects and greater effectiveness than older antipsychotic drugs in relieving
    negative symptoms of schizophrenia?
    A) Chlorpromazine (Thorazine)
    B) Clozapine (Clozaril)
    C) Thiothixene (Navane)
    D) Haloperidol (Haldol)
A

Ans: B
Feedback:
Advantages of clozapine include improvement of negative symptoms without causing the
extrapyramidal effects associated with older antipsychotic drugs. Chlorpromazine is a typical
antipsychotic, one of the older drugs, which does cause the extrapyramidal effects. Navane is part of the
thioxanthene group of typical antipsychotics. This group of drugs has low sedative and hypotensive
effects but can cause extrapyramidal effects. Haloperidol is a butyrophenone group drug used in
psychiatric disorders. Usually, it produces a relatively low incidence of hypotension and sedation and a
high incidence of extrapyramidal effects.

17
Q
  1. The nurse, providing teaching about a typical antipsychotic newly prescribed for the patient, cautions
    against use of alcohol with the drug by explaining it will have what effect?
    A) Prolonged QT interval
    B) Increased central nervous system (CNS) depression
    C) Increased anticholinergic effects
    D) Increased gastrointestinal (GI) adverse effects
A

Ans: B
Feedback:
Antipsychotic alcohol combinations combinations result in an increased risk of CNS depression, and
antipsychotic anticholinergic combinations lead to increased anticholinergic effects, so dosage
adjustments are necessary. Patients should not take thioridazine or ziprasidone with any other drug
associated with prolongation of the QT interval. Increase in GI adverse effects is not associated with
concurrent use of alcohol.

18
Q
  1. The nurse is caring for four patients. Which patient would the nurse know that clozapine (Clozaril) is
    contraindicated for?
    A) 17-year-old adolescent
    B) 23-year-old with diabetes insipidus
    C) 32-year-old with osteoarthritis
    D) 45-year-old with bone marrow depression
A

Ans: D
Feedback:
Clozapine is associated with bone marrow suppression, a life-threatening decrease in white blood cells.
Because of their wide-ranging adverse effects, antipsychotic drugs may cause or aggravate various
conditions. They should be used very cautiously in patients with liver damage, coronary artery disease,
cerebrovascular disease, Parkinsonism, bone marrow depression, severe hypotension or hypertension,
coma, or severely depressed states. Options A, B, and C are incorrect.

19
Q
19. The physician has ordered olanzapine (Zyprexa) for a new patient. What laboratory test should be done
before administration of olanzapine?
A) Blood glucose
B) Urine specific gravity
C) Cholesterol
D) Hemoglobin and hematocrit
A

Ans: A
Feedback:
Olanzapine has been associated with weight gain, hyperglycemia, and initiation or aggravation of
diabetes mellitus. Other options are not necessary for patients taking olanzapine unless a secondary
diagnosis indicates a need.

20
Q
  1. Parents bring a 15-year-old boy into the clinic. The parents tell the nurse that there is a family history of
    schizophrenia and they fear their son has developed the disease. What symptoms, if described by the
    family, would support their conclusion?
    A) He hears and interacts with voices no one else can hear.
    B) He is overactive and always so excitable.
    C) He falls asleep in the middle of a sentence.
    D) He cannot concentrate and his grades are suffering.
A

Ans: A
Feedback:
Characteristics of schizophrenia include hallucinations, paranoia, delusions, speech abnormalities, and
affective problems. Overactivity and excitement are associated with mania. Falling asleep suddenly describes narcolepsy. Difficulty concentrating and failing grades is associated with attention deficient
disorders.

21
Q
  1. The patient taking an antipsychotic drug asks the nurse how long he will continue to feel the effects of
    the drug after stopping the medication. What is the nurse’s best response?
    A) 2 to 4 hours
    B) 2 to 4 weeks
    C) 2 to 4 months
    D) 6 months
A

Ans: D
Feedback:
The antipsychotics are widely distributed in the tissues and are often stored there, being released for up
to 6 months after the drug therapy has been stopped

22
Q
  1. The nurse works on an inpatient mental health unit. When administering antipsychotic medications,
    what patient would the nurse expect to require a standard dosage?
    A) African American adolescent diagnosed with schizophrenia
    B) Malaysian middle adult diagnosed with bipolar disorder
    C) Iranian older adult diagnosed with schizophrenia
    D) Caucasian young adult diagnosed with bipolar disorder
A

Ans: D
Feedback:
Only the Caucasian young adult has no indications for administering a smaller than usual dosage.
African Americans respond more rapidly to antipsychotic medications and have a greater risk for
development of disfiguring adverse effects, such as tardive dyskinesia. Consequently, these patients
should be started off at the lowest possible dose and monitored closely. Patients in Asian countries
(e.g., India, Turkey, Malaysia, China, Japan, Indonesia) receive lower doses of neuroleptics and lithium
to achieve the same therapeutic response as seen in patients in the United States. Arab American
patients metabolize antipsychotic medications more slowly than Asian Americans do and may require
lower doses to achieve the same therapeutic effects as in Caucasians.

23
Q
23. Psychosis is a severe mental illness characterized by what?
A) Disordered thought
B) Increased social interaction
C) Hypoactivity with aggressiveness
D) Paranoid hallucinations
A

Ans: A
Feedback:
Antipsychotic drugs are used mainly for the treatment of psychosis, a severe mental disorder
characterized by disordered thought processes; blunted or inappropriate emotional responses; bizarre
behavior ranging from hypoactivity to hyperactivity with agitation, aggressiveness, hostility, and
combativeness; social withdrawal in which a person pays less-than-normal attention to the environment
and other people; deterioration from previous levels of occupational and social functioning (poor selfcare
and interpersonal skills); hallucinations; and paranoid delusions.

24
Q
  1. The nurse is caring for a patient newly diagnosed with schizophrenia. His parents say they have heard
    the term before but do not really understand exactly what schizophrenia means. How would the nurse
    describe the disorder? (Select all that apply.)
    A) Thought disorder
    B) Difficulty functioning in society
    C) Hallucinations can be auditory, visual, or sensory
    D) Can be cured with the correct medications
    E) Enter into fugue state in most cases
A

Ans: A, B, C, D
Feedback:
Mental disorders are thought process disorders that may be caused by some inherent dysfunction within
the brain. A psychosis is a thought disorder, and schizophrenia is the most common psychosis in which
delusions and hallucinations are hallmarks. Hallucinations can be auditory, visual, or sensory. Patients
diagnosed with schizophrenia have difficulty functioning in society. Schizophrenic patients do not
generally go into fugue states and it certainly is not a common disorder.

25
Q
  1. A 7-year-old boy is admitted to the pediatric behavioral health unit with a diagnosis of an acute
    psychotic episode. Aripiprazole has been ordered. Before administering the medication, what is the nurse’s first priority?
    A) Weigh the patient.
    B) Obtain baseline vital signs.
    C) Call the physician.
    D) Administer the medication between meals
A

Ans: C
Feedback:
Of the antipsychotics, chlorpromazine, haloperidol, pimozide, prochlorperazine, risperidone,
thioridazine, and trifluoperazine are the only ones with established pediatric regimens. Aripiprazole has
dosages for children 13 to 17 years of age but would not be appropriate for a 7-year-old child.
Weighing the patient and obtaining baseline vital signs is necessary assessment data but is not the first
priority. There is nothing to indicate medications should be administered between meals.

26
Q
  1. The nurse admits a patient newly diagnosed with schizophrenia to the inpatient mental health unit.
    What is the priority reason for why the nurse includes the family when collecting the nursing history?
    A) The patient may not be able to provide a coherent history.
    B) The patient may not be able to speak due to reduced level of consciousness.
    C) The family will feel better if they are included in the process.
    D) The patient will be less anxious if the family listens while he answers questions.
A

Ans: A
Feedback:
Schizophrenia, the most common psychosis, is characterized by delusions, hallucinations, and
inappropriate responses to stimuli. As a result, the patient may be unable to provide a coherent history
and may be unaware of his behaviors considered dysfunctional. There is no reason to suspect the
patient cannot speak and reducing anxiety is not the priority rationale for including family. While
family is included in treatment, the goal is to treat the patient and not make the family feel better if
actions were not in the patient’s best interests.

27
Q
  1. The nurse is teaching the soon-to-be-discharged patient, diagnosed with schizophrenia, about his
    medications. What is a priority teaching point for this patient?
    A) The patient must eat three nutritious meals daily.
    B) Over-the-counter medications may be taken with antipsychotic drugs.
    C) Cough medicines potentiate the actions of antipsychotic drugs.
    D) Alcohol consumption should be avoided.
A

Ans: D
Feedback:
Alcohol consumption should be avoided because it increases the central nervous system (CNS) effects
of the drug and may cause excessive drowsiness and decreased awareness of safety hazards in the
environment. Some patients may find it easier and more effective to eat five small meals rather than
three nutritious meals. While promoting good nutrition is good practice, it is not the priority. Drug drug
interactions with antipsychotic drugs are common so the nurse would teach the patient not to take any
medication without consulting with the doctor or a pharmacist to make sure it is safe.

28
Q
28. What antiepileptic medication might the nurse administer to treat bipolar disorder?
A) Apriprazole (Abilify)
B) Cyclobenzaprine (Flexeril)
C) Lamotrigine (Lamictal)
D) Temazepam (Restoril)
A

Ans: C
Feedback:
Lamotrigine is an antiepileptic agent used for long-term maintenance of patients with bipolar disorders
because it decreases occurrence of acute mood episodes. Apriprazole is an atypical antipsychotic and is
not an antiepileptic medication. Flexeril is a muscle relaxant and Temazepam is a hypnotic agent. None
of these medications are indicated for the treatment of bipolar disorder.

29
Q
  1. A patient, who is 77 years old, is admitted with a diagnosis of dementia. Haloperidol (Haldol) has been
    ordered for this patient. What nursing considerations would govern the nurse’s actions? (Select all that
    apply.)
    A) It is classed as an atypical antipsychotic.
    B) A lowered dosage is indicated for older adult.
    C) It often has a hyperactive effect on patients.
    D) It should not be used to control behavior with dementia.
    E) It should only be given every other day.
A

Ans: B, D
Feedback:
Haloperidol is classified as a typical antipsychotic with a high risk of extrapyramidal effects and lower
risk for hypotension and sedation. Older patients may be more susceptible to the adverse effects of
antipsychotic drugs. All dosages need to be reduced and patients monitored very closely for toxic
effects and to provide safety measures if central nervous system effects do occur. They should not be
used to control behavior with dementia. Haloperidol does not have a hyperactive effect on patients; it
should not be given on an every-other-day schedule.

30
Q
30. Which drug does not have a recommended pediatric dose?
A) Pimozide (Orap)
B) Lithium salts (Lithotabs)
C) Haloperidol (Haldol)
D) Risperidone (Risperdal)
A

Ans: B
Feedback:
Lithium does not have a recommended pediatric dose; the drug should not be administered to children
younger than 12 years old. Pimozide, haloperidol, and risperidone all have recommended pediatric
doses.

31
Q
  1. The mother of a child diagnosed with attention-deficit syndrome receives a prescription for a central
    nervous system (CNS) stimulant to treat her child. The mother asks the nurse, I don’t understand why
    we’re giving a stimulant to calm him down? What is the nurse’s best response to this mother?
    A) It helps the reticular activating system (RAS), a part of the brain, to be more selective in response
    to incoming stimuli.
    B) It helps energize the child so they use up all of their available energy and then they can focus on
    quieter stimuli.
    C) No one truly understands why it works but it has been demonstrated to be very effective in treating ADHD.
    D) The drugs work really well and you will see a tremendous change in your child within a few weeks
    without any other treatment
A

Ans: A
Feedback:
The paradoxical effect of calming hyperexcitability through CNS stimulation seen in attention-deficit
syndrome is believed to be related to increased stimulation of an immature RAS, which leads to the
ability to be more selective in response to incoming stimuli. CNS stimulants do not cause the child to
use all his energy, the effect is thought to be understood, and telling the mother the drug just works
without any explanation is not appropriate and may result in noncompliance with pharmacology
therapy if the mother does not understand why the drug is given.

32
Q
  1. The nurse is teaching the mother of a child diagnosed with attention-deficit hyperactivity disorder how
    to administer methylphenidate (Ritalin). When would the nurse instruct the mother to administer this
    drug?
    A) Administer at lunch every day.
    B) Administer at breakfast every day.
    C) Administer at dinner every day.
    D) Administer at bedtime.
A

Ans: B
Feedback:
Several long-acting formulations of methylphenidate have become available that allow the drug to be
given only once a day. It should always be given in the morning because administration at dinnertime
or bedtime could result in insomnia.

33
Q
  1. A child was diagnosed with attention-deficit hyperactivity disorder and methylphenidate was
    prescribed for treatment to be taken once a day in a sustained release form. On future visits what is a
    priority nursing assessment for this child?
    A) Weight and height
    B) Breath sounds and respiratory rate
    C) Urine output and kidney function
    D) Electrocardiogram (ECG) and echocardiogram
A

Ans: A
Feedback:
The nurse needs to carefully track this child’s weight and height because the drug can cause weight
loss, anorexia, and nausea that could result in slowed or absent growth. There would be no need to
monitor breath sounds, respiratory rate, urine output, and kidney function. Although arrhythmias may
occur as an adverse effect necessitating an ECG, there is no need to perform echocardiograms.

34
Q
  1. The nurse is preparing to administer methylphenidate to the child admitted to the pediatric unit after
    breaking a leg when jumping off the garage roof at home. Where will the nurse find the medication?
    A) In the patient’s drawer
    B) In the refrigerator
    C) At the patient’s bedside
    D) In the controlled substance cabinet
A

Ans: D
Feedback:
Methylphenidate is a controlled medication due to risk for physical and psychological dependence. As a
result, the drug would be found in the controlled substance cabinet.

35
Q
  1. The nurse is caring for a child receiving a central nervous system (CNS) stimulant who was admitted to
    the pediatric intensive care unit following repeated seizures after a closed head injury. The physician
    orders phenytoin to control seizures and lorazepam to be administered every time the child has a
    seizure. What is the nurse’s priority action?
    A) Call the doctor and question the administration of phenytoin.
    B) Call the doctor and question the administration of lorazepam.
    C) Wait 24 hours before beginning to administer phenytoin.
    D) Wait 24 hours before beginning to administer lorazepam.
A

Ans: A
Feedback: The combination of CNS stimulants with phenytoin leads to a risk of increased drug levels. Patients
who receive such a combination should be monitored for toxicity. There is no contraindication for use
of lorazepam.