Unit 5: Cancer Flashcards

1
Q

Explain what cancer is.

What is metastasis and explain how it occurs.

A

Cancer is the abnormal, uncontrolled multiplication of cells due to DNA mutations that disrupt the cell cycle

Primary tumor is established and recruits normal cells as envoys

Cancer cells don’t stick as well to each other as normal cells do, so they break off easily, cancer cells float freely

Normal cells will relocate and attract free-floating cancer cells, forming a secondary tumor

Metastasis continues past secondary tumor

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2
Q

How can tumors (cancer) damage the body?

A

Tumors can block blood/lymphatic vessels and interfere with body function

Advanced tumors can use up supplies of energy and nutrients meant for healthy cells

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3
Q

How does a tumor form from cancer?

What are the two types of tumors?

A

Cells multiply rapidly with no checkpoints, eventually forming a tumor

Benign (non-spreading and local, less dangerous but still is), Malignant (spreads, more dangerous)

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4
Q

What are the 4 types of malignant tumors?

Explain what each arise in

A

Carcinomas: Arise from epithelia, tissue that surrounds/protects

Sarcomas : Arise from bone, cartilage, striated muscle

Lymphomas: Arise in the lymphatic tissue

Leukemia: Arise in blood-forming cells, usually in the bone marrow

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5
Q

Describe skin cancer. What is it known for?

What are the 2 common types of cancer?

A

Highest incidence but mostly cured

Basal cell carcinomas, squamous cell carcinomas

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6
Q

What are risk factors, prevention methods and treatments to skin cancer?

A

Risk factors: light skin, hair and eye colour, history of UV exposure and burning, lots of moles, tendency to burn in the sun, tendency to form freckles, family history

Treatments: surgery, immunotherapy

Preventions: sunscreen, avoiding UV light exposure and tanning lamps

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7
Q

What are signs/symptoms of skin cancer?

A
  • moles, sores, and spots changing colour, shape, symmetry, size
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8
Q

What is breast cancer known for?

A

Most common cancer in women after non-malignant skin cancer

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9
Q

What are risk factors, prevention methods and treatments to breast cancer?

A

Risk factors: genetics, age, age at menopause, lifetime exposure to estrogen

Treatments: chemo, surgical removal, radiation, SERMS (drugs)

Prevention: regular screenings

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10
Q

What are signs/symptoms of breast cancer?

A

lump (through mammogram), irritation, thickening of tissue, swelling, nipple pain

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11
Q

When does breast and prostate cancer become dangerous? What is the survival rate before this happens?

A

Dangerous when it metastasizes
Breast cancer: >80% survival rate
Prostate cancer: >95% survival rate

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12
Q

What is prostate cancer known for?

A

Most common cancer in M (apart from non-malignant skin cancer)

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13
Q

Where is the prostate located?

A

Prostate located on base of bladder, surrounds urethra

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14
Q

What are risk factors, prevention methods and treatments to prostate cancer?

A

Risk factors: history of STIs, diet, physical inactivity, obesity, age

Treatments: cryotherapy, radiation, drugs, surgery

Preventions: digital rectal screening, prostate-specific antigen

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15
Q

What are signs/symptoms of prostate cancer?

A

usually none, but sometimes abnormal urine flow

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16
Q

What is lung cancer known for?

After diagnosis, what is the survival rate?

A

Cancer with most deaths

5 years after diagnosis: 20% survival rate

17
Q

What are risk factors, prevention methods and treatments to lung cancer?

A

Risk factors: Carcinogens: smoking, second-hand smoking, asbestos, pollution

Treatments: surgery, chemo, radiation

Preventions: CT scanning, x-ray

18
Q

Signs/symptoms for lung cancer

A

reoccurring cough, bronchitis, chest pain

19
Q

What is colorectal cancer known for?

Describe it (in terms of polyps, stages, etc.)

A

3rd most common cancer in men and women

Forms polyps in beginning stages

Stage IV is cancerous

20
Q

What are risk factors, prevention methods and treatments to colorectal?

A

Risk factors: inflammatory bowel disease, older age, red/processed meats, male sex

Treatments: Surgery, chemo, radiation

Preventions: Fecal blood screening, endoscopic techniques

21
Q

Signs/symptoms for colorectal cancer

A

pain, irregular bowel movement

22
Q

Where is the cervix?

How can cervical cancer be transmitted?

A

Cervix is between vagina and uterus

skin-skin contact

23
Q

What are risk factors, prevention methods and treatments to cervical cancer?

A

Risk Factors: HPV, smoking

Treatments: surgery, chemo, cryotherapy, laser treatment

Preventions: regular pap tests, HPV vacc.

24
Q

Describe the PROCESS in which cancer is detected, diagnosed and treated.

Explain an example for breast cancer.

A

Apparently healthy population gets regular screening

Those who test negative will go back to the pool of apparently healthy and will retake screening again later, those who test positive will move on to testing

Pool of people who tested positive will move onto testing. Those who test positive for the disease will move to treatment and those who test negative for specific disease will move back to apparently healthy population and will screen again later

screening: mammogram
testing: biopsy

25
Explain the difference between screening and testing
Screening is a more general test * Inexpensive, non-invasive Testing is more specific for diseases * Costly, usually invasive
26
# Cancer treatments Describe chemotherapy ## Footnote What are its side effects and what is it most effective for?
**Drugs with purpose of specifically targeting and killing cancerous cells** * Attacks any rapidly multiplying cells, so can attack healthy cells too * Ex. hair cells and digestive cells **Side effects**: loss of hair, nausea, fatigue **Most effective for**: metastasized cells
27
# Cancer treatments Describe radiation ## Footnote What are possible side effects?
Purpose is to bombard cancerous cells at all directions with beams to kill them Can kill healthy cells as well so it also has side effects
28
# Cancer treatments Describe surgery
Physical removal of cancerous cells Purpose is to minimize tumors to prepare for chemo or radiation, or to remove remaining tumors as a result of chemo or radiation
29
# Cancer treatments Immunotherapy
Purpose is to boost immune system Effective on infection founded cancers
30
# Cancer treatments Hormone therapy | What is it specific for? What does it do specifically?
Specific for cancers that are aided by hormones Blocks hormone receptors
31
# Cancer treatments Gene therapy ## Footnote What technology is an example of this?
Modify DNA, targeting cancer or immune cells to fight off cancerous ones Ex. CRISPR
32
List specific actions you can take to lower your risk of cancer
* Avoiding carcinogens: smoking, asbestos, pollution, UV light, radiation * Maintaining healthy weight and diet: antioxidants, limit alcohol use, avoiding burnt food * Getting vaccinated regularly * Getting screenings