Unit 4 - Immunology Flashcards

1
Q

Describe what is meant by the term ‘non-specific’ as applied to cells?

A

The defenses are general, all invading pathogens

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2
Q

Explain how tissues can provide a physical defense against infection

A

The epithelium can form a barrier preventing the entry of pathogens

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3
Q

Name two secretions from epithelial cells cells that provide defense against infection.

A

Mucus secreted from the breathing tube epithelium

Acid secreted by the cells in the stomach epithelium

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4
Q

Name the molecules present on the surface of pathogens that phagocytes recognise

A

Antigens

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5
Q

Define apoptosis

A

Induced cell suicide

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6
Q

Define immune surveillance

A

A range of white blood cells constantly patrolling and monitoring the tissues

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7
Q

Describe the role of cytokines in defense

A

They are signal molecules;

They increase blood flow to the infected site

They activate white blood cells

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8
Q

Define ‘allergic response’

A

The hypersensitive B lymphocyte response to a normally harmless antigen

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9
Q

Define ‘autoimmune response’

A

Immune system regulation failure;

Leads to response of T lymphocytes to self antigens

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10
Q

Define ‘immunological memory’

A

A long term existence of memory cells following a primary exposure to antigens, allows rapid, greater immune response to secondary exposure to the same antigen

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11
Q

Name two microorganisms that act as pathogens

A

Bacteria & virus

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12
Q

Name two transmission methods

A

Direct contact - shaking hands

Exchanging fluids - secretion

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13
Q

Define quarantine

A

Enforced isolation of individual to prevent spreading of infectious diseases

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14
Q

Define antisepsis

A

Practises that destroy pathogens or inhibit their growth

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15
Q

Describe individual responsibility of prevention of spread of infection

A

Personal hygiene and sexual health

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16
Q

Describe the communities responsibility to control spread of infection

A

Providing high quality water supplies
Safe food webs
Safe sewage disposal

17
Q

Describe ‘vaccine’

A

Pharmaceutical that produce an immune response without symptoms of disease

18
Q

Explain the role of adjuvants in immunity

A

Added to vaccines to enhance the immune response

19
Q

Define double blind

A

When the participant and administrator don’t know if the participant is receiving a placebo or vaccination

20
Q

Define placebo control

A

Some participants receive a placebo rather than vaccine under trial

21
Q

How can pathogens evade human immunological memory system?

A

They change their antigen constantly

They can survive within host cells