unit 4 drugs

Question 1

long-term control agent, glucocorticoid, suppress immune system cells, first line agent for asthma control, reduces hyperactivity of airways, can cause oral candidiasis and hoarseness

Answer 1

fluticasone

Question 2

non-selective first generation antihistamine (H1 and H2), for allergic rhinitis, pruritus, urticaria, can cause sedation and be antiholinergic

Answer 2

diphenhydramine (first gen)

Question 3

anti-leukotriene, inhibit CysLT1 receptor signaling, competitive inhibitor, control mild to moderate asthma, bronchodilation, useful for patients that can’t tolerate glucocorticoids, only about 50% people respond

Answer 3

montelukast (antagonist)

Question 4

Rx only, COX-2 selective NSAID, low GI risk, high CV risk

Answer 4

celecoxib

Question 5

SGLT2 inhibitor, inhibit glucose reabsorption in kidney, leads to purposeful glucose in urine, needs to be accompanied by fluid replenishment, cause weight loss and UTI, help heart failure

Answer 5

canaglifozin

Question 6

orally bioavailable, DPP-4 inhibitor secretagogue for insulin

Answer 6

sitaglipin

Question 7

sulfunyl urea K ATP secretagogues for insulin, enhance insulin secretion

Answer 7

glipizide

Question 8

glucocorticoid given for long-term asthma, suppress immune system cells, first line agent for long-term asthma, reduced hyperreactivity of airways, can cause oral candidiasis and hoarseness

Answer 8

beclomethasone