Unit 3.5.4 - Homeostasis Flashcards

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1
Q

What is homeostasis?

A

Maintenance of a constant internal environment.

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2
Q

What is meant by homeostasis keeps your internal environment in a state of dynamic equilibrium?

A

It fluctuates about it’s normal level.

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3
Q

Why is keeping the internal environment constant vital in the body?

A

Allows cells to function normally and stops them being damaged.

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4
Q

What three things have to be particularly controlled in the body?

A

Core body temperature, blood pH and blood glucose concentration.

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5
Q

What do both temperature and pH affect?

A

Enzymes that control the rate of metabolic reactions.

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6
Q

What happens to the rate of metabolic reaction as temperature increases up to the optimum temperature.

A

Molecules have more kinetic energy so move faster, this means there will be more collisions and the energy of the collisions will increase so a reaction will be more likely so the rate of reaction increases.

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7
Q

What happens to the rate of metabolic reactions once temperature is increased passed the optimum temperature?

A

When the temperature is too high it starts to interfere with the hydrogen bonds that hold the enzyme together so the enzyme and it’s active site will start to change shape. This means the enzyme and sub straight will no longer be complimentary and they can’t form E-S complexes and so the enzyme will be denatured and rate of reaction would decrease.

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8
Q

Why is the rate of reaction low at low temperatures?

A

Reduced enzyme activity.

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9
Q

How is the rate of metabolic reactions affected if the blood pH is too high or too low.

A

The pH starts to interfere with the hydrogen bonds holding the enzyme together so the enzyme and it’s active site will start to change shape. This means the enzyme and sub straight will no longer be complimentary and they can’t form E-S complexes and so the enzyme will be denatured and rate of reaction would decrease.

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10
Q

What happens to cell if blood glucose concentration is too high?

A

The water potential of the blood is reduced to a point where water molecules diffuse out of the cell into the blood by osmosis causing the cell to shrivel up and die.

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11
Q

What happens to cells if the blood glucose concentration is too low?

A

The cell is unable to carry out normal activities because there isn’t enough glucose for respiration to provide energy.

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12
Q

What are the two different classifications for animals which depends on how they control their body temperature?

A

Ectotherms and endotherms.

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13
Q

How do ectotherms control their body temp?

A

By changing their behaviour.

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14
Q

What does the internal temp of ectotherms depend on?

A

The external temp.

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15
Q

Why do ectotherms have variable metabolic rates?

A

Because they can’t keep their internal temp constant.

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16
Q

Do the activity ectotherms or endotherms depend on the external temp?

A

Ectotherms

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17
Q

How do endotherms control their body temp?

A

Homeostasis as well as altering their behaviour.

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18
Q

Is the internal temp of ectotherms or endotherms most affected by external temp?

A

Ectotherms

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19
Q

Why do endotherms have a high metabolic rate?

A

They can keep their internal temp constant.

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20
Q

What things do mammals try to control to control body temp?

A

Heat loss, heat production and heat conservation - Hollie is a very annoying girl!

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21
Q

What three things can increase heat loss?

A
  1. Opening the windows
  2. Sweating
  3. Hairs lying flat against the skin
  4. Vasodilation
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22
Q

How does sweating increase heat loss?

A

It smells and more sweat will be secreted from sweat glands and the water in the sweat evaporates from the surface of the skin taking heat from the body with it.

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23
Q

How do hairs lying flat against the skin increase heat loss?

A

Ask Hollie as Hollie’s legs are very hairy

Erector pili muscles relax so the hairs lie flat against the skin so less air is trapped and the skin is less insulated

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24
Q

What is vasodilation?

A

When the arterioles near the surface of the skin dilate.

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25
Q

Why does vasodilation increase heat loss?

A

More blood flows through the blood capillaries in the surface layer of the dermis. This means more heat can be lost from the skin by radiation.

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26
Q

What two things can increase heat production?

A

Shivering and hormones.

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27
Q

How does shivering increase heat production?

A

Because mum puts heating up

Muscles contract in spasms, this makes the body shiver, this requires energy from respiration so more heat is produced.

28
Q

How do hormones increase heat production?

A

The body releases adrenalin, this increase metabolism so more heat is produced.

29
Q

What three ways can heat be conserved?

A
  1. Shut the windows
  2. Sweating less
  3. Hairs standing up
  4. Vasoconstriction
30
Q

How does hair standing up conserve heat?

A

The erector pili muscles contract when it is cold which makes the hair stand up. This traps more air which provides more insulation.

31
Q

What is vasoconstriction?

A

The arterioles near the surface of the skin constrict.

32
Q

How does vasoconstriction conserve heat?

A

Less blood flows through the capillaries in the surface layer of the dermis reducing heat loss.

33
Q

What is control of body temp known as?

A

Thermoregulation.

34
Q

What part of the brain controls the body temp?

A

Hypothalmus

35
Q

What receptors detect internal and external temp?

A

Thermoreceptors

36
Q

What part of the nervous system regulates body temp?

A

The autonomic system

37
Q

What type of feedback is there in regulating body temp?

A

Negative.

38
Q

What organ monitors blood glucose concentration?

A

Pancreas

39
Q

What activity causes your blood glucose concentration to increase?

A

Eating foods that contain carbohydrates

40
Q

What activity to causes your blood glucose concentration to decrease?

A

Respiration - excessive exercise.

41
Q

What two hormones control blood glucose concentration?

A

Insulin and glucagon

42
Q

What cluster of cells release insulin and glucagon?

A

Islets of langerhans

43
Q

What cells secrete glucagon?

A

Alpha cells

44
Q

What cells secrete insulin?

A

Beta cells

45
Q

What are the seven steps in how insulin reduces blood glucose concentration?

A
  1. The pancreas detects the rise in BGC
  2. Beta cells within the islets of Langerhans secrete insulin into the blood
  3. Insulin binds to the complimentary in shape receptors onto the target cell
  4. This cause more glucose channel proteins to be opened and synthasised which increase the permeability of the cell membrane to glucose.
  5. Glucose diffuses down the concentration gradient into the target cell and is converted to glycogen.
    6 .This maintains the concentration gradient so glucose can continue to diffuse into the cell.
  6. This decreased the BGC back to it’s original level.
46
Q

What is the process called of converting glucose to glycogen?

A

Glycogenesis

47
Q

What is glycogenesis?

A

The process of converting glucose to glycogen

48
Q

What are the two processes that BGC is increased by?

A

Glycogenolysis and Gluconeogenesis

49
Q

In 7 steps how does Glucagon decrease BGC during glycogenolysis?

A
  1. The pancreas detects the fall in BGC.
  2. Alpha cells within the islets of Langerhands secrete glucagon into the blood
  3. Glucagon binds to the complimentary in shape receptors on the target cells
  4. This binding activates the enzyme adenylate cyclase which converts ATP to cAMP.
  5. cAMP diffuses into target cells
  6. cAMP then activates a cascade that breaks down glycogen into glucose.
  7. Which increases the BGC back to its original level.
50
Q

What is glycogenolysis?

A

A process of converting glycogen into glucose

51
Q

What is gluconeogenesis?

A

The formation of glucose from glycerol and amino acids.

52
Q

Why is glycogenolysis also called the secondary messenger model?

A

Glucagon doesn’t cause the effect it activates another enzyme which then activates the effect.

53
Q

What process is adrenalin the same as?

A

The secondary messenger model

54
Q

What is adrenalin?

A

A hormone secreted from your adrenal gland.

55
Q

When is adrenalin secreted?

A

When there is a low concentration of glucose in your blood so when you are stressed or during exercise.

56
Q

How does the adrenalin get the body ready for action?

A

Makes more glucose available for muscles to respire.

57
Q

Other than producing more glucose what does adrenalin also do?

A

Inhibit the production of insulin.

58
Q

What is diabetes?

A

A condition where BGC cant be controlled properly

59
Q

What are the two types of diabetes?

A

Type 1 and Type 2

60
Q

What is type 1 diabetes caused by?

A

When beta cells stop producing insulin.

61
Q

How can you treat type 1 diabetes?

A

Regular injections of insulin.

62
Q

How can you avoid sudden rises in blood glucose levels?

A

Eating regular and controlling sugar intake

63
Q

What is Type 2 diabetes caused by?

A

Beta cells don’t produce enough insulin or when the body cells don’t respond properly to insulin.

64
Q

Why might cells not respond properly to insulin?

A

Receptors on their membranes don’t work properly or the cells don’t take up enough glucose.

65
Q

What is type 2 diabetes often linked with?

A

obesity

66
Q

What 3 ways can type 2 diabetes be controlled?

A
  1. Controlling sugar intake
  2. Losing weight
  3. Glucose lowering tablets