UNIT 3- GU OVERVIEW AND ASSESSMENT Flashcards
What are the functions of the kidney?
- Regulate the volume and composition of extracellular fluid (EFC)
- Excrete waste products from the body
- Control BP
- Erythropoietin production
- Vitamin D Activation
- Acid-Base Balance regulation
What do we need to know about urine formation?
Urine formation is the outcome of a complex, multistep process of filtration, reabsorption, secretion and excretion of water, electrolyte and metabolic waste products.
- Glomerular filtration
- Tubular reabsorption
- Tubular secretion
- Urine concertation.
What is the function of the Glomerular?
- Blood is filtered by hydrostatic pressure
- Passes through bowman’s capsule
- Glomerular filtrate passes down tubule
What is the normal Glomerular filtration rate (GFR)?
125mL/min (this results in about 48 gallons filtered per day)
What should we know about tubular reabsorption?
Proximal convoluted tubule (PCT)–>most reabsorption will occur here (amino acids, sodium, chloride, and other essential nutrients)
Loop of Henle–> descending limb and ascending limb——–>located in the renal medulla (this is a VERY salty area—hypertonic (the interstitial fluid is hypertonic)– this is where a lot of your water absorption will occur (where the urine will get concentrated)
Nephron function: Note——->small amounts of waste products (ex: urea and creatinine) are okay to remain in the blood, but too much can be harmful. (This will be important when we discuss renal failure!)
Urine contains water, urea, sodium, potassium, chloride, creatinine and more! When a patient is not excreting these substances, it can be harmful.
How does ADH play a role in urine formation?
- Important in water balance/water reabsorption in the kidney
- Regulated by posterior pituitary gland
How is aldosterone important in the urine formation?
- Reabsorption of sodium and water
- Released from adrenal cortex
What is the function of Ureters?
- Carry urine from renal pelvis to the bladder
- Ureteral lumens are narrow
What should we know about the bladder?
- Reservoir for urine
- Capacity 600-1000mL
- Bladder muscle (detrusor)
- Urination Micturition, voiding
How long is a female urethra?
1-2 in (3-5cm)
How long is a males urethra?
8-10in (20-25cm)
What should we know about the Ureterovesical unit?
Formed by the bladder, urethra, and pelvic floor muscle
- Voluntary control of this unit is defined as continence
-Distention of bladder stimulates stretch receptors
-Impulses sent to brain.
Why is medication use important GU history?
To rule of contraindicated medications either due to reactions w/each other or potential side nephrotoxic agents
What are 4 examples of nephrotoxic agents
- Vancomycin
- Ampoterycin
- Cephalosporin
- Gentamycin
What is anuria?
Inability to pee
What is olguira?
Small amounts of urine
What is polyuria?
Lots of urine/frequent use