UNIT 2- PARKINSON'S DISEASE Flashcards
What is Parkinson’s disease?
It is a chronic progressive neurodegenerative disease of the CNS manifesting primarily in motor dysfunction
What is the typical age range for Parkinson’s disease dx?
40-70 years of age
What causes PD?
1.Exact cause is unknown
2. Possibly a result between environmental factors and a person genetic make up
3. Risk also increases by well water, pesticides, herbicides, industrial chemicals, wood pulp mills, Rual residence
What is atypical PD? and what are possible causes?
- Atypical PD is caused by various factors causing PD like s/s however once factors are treated or removed than the s/s improve and it deemed atypical PD. In true PD the s/s would not reside.
Possible causes include
1. Exposure to chemicals
2. Drug induced
3. Others
True or false: In PD patients will shake their heads as part of the tremors?
False- In PD people don’t shake their heads.
What is the patho of PD?
- Degeneration of dopamine producing neurons in substantia nigria of midbrain.
- Disrupts dopamine-acetylcholine balance in basal ganglia
- Essential for normal functioning of extrapyramidal motor system
When do clinical symptoms appear in PD?
Clinical symptoms appear with 60% neuron loss and 80% dopamine decrease
What are the clinical manifestations of PD? Think TRAP
T- Tremors (resting)
R- Rigidity
A- Akinesia/Bradykinesia
P- postural instability
What is the onset of symptoms like in PD?
Gradual and insidious w/ongoing progression
What are beginning stages of PD s/s?
- Mild tremor (resting),
2.slight limp,
3.decreased arm swing
What are the later stage s/s of PD?
- Shuffling
- Propulsive gait with arms fixed
- Loss of postural reflexes
Which increases drooling, aspiration risk, mask like facial feature
What should we know about PD tremors?
- Resting tremor/pill rolling hand tremor
- Often 1st sign of PD
- More prominent at rest
- Aggravated by emotional stress and increased concentration
What other areas can PD tremors effect in later stages?
- Diaphragm
- Tongue
- Lips
- Jaw may be involved
What should we know about rigidity in PD?
- Increased resistance to passive motion when limbs are moved through ROM
- Sustained muscle contraction
-Complaints of muscle soreness
-Feeling achy or tired
-pain in the head, upper body , spine or legs. - Slowness of movment
What is cogwheel rigidity?
Jerky quality- like intermittent catches in passive movement of a join
What is akinesia?
Absence or loss of control of voluntary muscle movements