Unit 3: Cellular Energetics Flashcards
enzymes
biological catalysts made of proteins with 3D tertiary structure specific to their function
ribozymes
biological catalysts made of RNA
active site
interacts with substrate; shape and charge of active site must match substrate to interact
substrate
reactant of enzyme; specific to shape and charge of active site
enzymes catalyze reactions most efficiently at…
optimum temperatures and pHs that are specific to the enzyme
if the temperature in the environment is too low…
the rate of collisions between the enzyme and its substrate will be reduced, slowing the reaction
if the temperature in the environment is too high…
bonds that hold the enzyme together may be disrupted, and the enzyme’s shape can be altered
a pH too far from optimum can…
disrupt bonds in the enzyme and result in a change in its tertiary structure
denaturation
change to an enzyme’s structure, which can limit the enzyme’s ability to catalyze chemical reactions; this can sometimes be reversed when optimum conditions are reached
competitive inhibitors
- similar in shape to substrates and compete with them for the active site of an enzyme
- competition lowers the rate of enzyme-catalyzed reactions
- the effect of competitive inhibitors can be diluted by adding higher concentrations of substrate so that the substrates can outcompete the inhibitors
noncompetitive (allosteric) inhibitors
- bind to the allosteric site of an enzyme
- binding changes the shape of the enzyme, affecting its function
- adding higher concentrations of substrate does not affect the actions of a noncompetitive inhibitor
- function in feedback mechanisms, adjusting the rate of chemical reactions in the cell to suit changing environmental conditions
cofactors
inorganic molecules that increase the efficiency of enzyme-catalyzed reactions by binding to active site or substrate to enhance the binding of the substrate to the active site
coenzymes
organic molecules that increase the efficiency of enzyme-catalyzed reactions by binding to active site or substrate to enhance the binding of the substrate to the active site
endergonic reactions
products with higher free energy level than its reactants; considered energetically unfavorable
exergonic reactions
products with lower free energy level than its reactants; considered energetically favorable