Unit 2 Topic 1: Homeostasis Flashcards
Homeostasis
the maintenance of relatively stable internal conditions within narrow tolerance limits via negative feedback mechanism.
receptors
thermoreceptor - temperature
nociceptor - pain
photo - light
mechano - pressure
chemo - chemicals
effectors
muscles - contract
glands: endo and exocrine
metabolism
sum of the net chemical processes in the body
changes in metabolic activity and catalytic activity
- enzymes denature from metabolic heat
- decreased means dereased ROR
CNS
brain
spinal chord
interconnecting neurons
PNS
the rest of the body, motor and sensory neurons
myelin sheath
- insulates and protects signa;
- speeds up transmission of signal
Nerve impulse transmission within neuron
resting potential:
more negative inside, 2K in and 3Na out
action potential:
K gates close, Na gates open, influx of ions, becomes more negative on outside.
repolarisation:
k gates open again
Na gates close
active pumping begins again
between neurons
actional potential arrives at the presynaptic terminal of the neuron where synaptic vessels with the neurotransmitters fuse with the terminal and diffuse into the synaptic cleft, here they bind to the receptors on the postsynaptic neurpn where the signal changes from chemical to electrical (signal transduction).
hormones
are chemical messengers released from glands that prompt a response from specific cells.
they only act upon cells with the complementary receptor.
water soluble hormones
binds extracellularly, from amino acids.
1. ion channel receptor
2. G protein couples receptor
3. tyrosine kinase
fat soluble hormones
bind intracellularly, drived from glycerol and fatty acids
how does receptor binding activate signal transduction
- binding
- activation
- signal transduction
- amplification (second messengers)
- changes in cellular activity
- negative feedback
heat loss and gains
endotherms: regulate internal temp
exotherms: internal temp is affected by environmental conditions