Unit 2: Section 2 - Genetics Flashcards
Which nitrogenous bases specific base pair to each other?
Adenine and Thymine (A-T)
Cytosine and Guanine (C-G)
What 3 main things is a nucleotide made up of?
- phosphate group
- deoxyribose sugar
- nitrogenous base (varies, either A T C or G)
How many hydrogen bonds between the base pairs?
2 A-T
3 C-G
Give 3 ways DNA is well adapted for it’s function
- helical shape, makes it compact
- strong covalently bonded sugar-phosphate backbone in a double helix to protect genetic material
- genetic information (organic bases) have paired structure which makes it much easier to copy itself (self replication)
How is DNA stored in eukaryotic cells?
- DNA in double helix
- wound around proteins called histones
- histones also help to support DNA
- DNA wound round histones is coiled up repeatedly
- this forms a single chromosome
How is DNA stored in prokaryotic cells?
- same DNA double helix
- forms circular chromosome
- this is then coiled
- then supercoiled (like a snake to fit in cell)
How many organic bases form an amino acid?
3
Which two areas of DNA in eukaryotic cells don’t code for amino acids?
- DNA sections called introns
- DNA regions with multiple repeats outside of genes e.g. CCTTCCTTCCTT
How does DNA affect our nature, development and phenotype?
- DNA codes for certain alleles which control charecteristics e.g. Eye colour
- DNA determines amino acid sequence
- determines proteins and enzymes formed
- enzymes control metabolic pathways
- metabolic pathways help determine nature, phenotype and development
How can mutation cause none functional enzyme?
- deletion, addition, repetition of organic base
- change in amino acid sequence
- produces new allele which codes for protein
- enzyme is protein, if allele is different a different enzyme is produced
- because of different amino acid sequence it may not fold up properly
- different tertiary structure, active site different shape, not complementary to substrate
- cannot form enzyme-substrate complex
What is a haploid and diploid cell?
Diploid: number of chromosomes in normal body cells, have 2 of each chromosome (2n) one from mum, one from dad
Haploid: number of chromosomes in gamete, only one of each chromosome (only half from mum ovum or only half from dad sperm) (n)
What is an allele?
Different forms of the same gene
How many devisions in meiosis?
2
What is the centre of the double-armed chromosomes called?
Centromere
What is the single strand in a double-armed chromosome called?
Chromatid