Unit 2 - Physiology and Health Flashcards
What causes puberty?
The release of releaser hormones from the hippocampus causes the pituitary gland to produced hormones follicle stimulating hormone, luteinising hormone/interstitial cell stimulating hormone.
In males, what does follicle stimulating hormone do?
Promotes sperm production in the seminiferous tubes
In males, what does interstitial cell stimulating hormone do?
Promotes testosterone production in the seminiferous tubes
Where is sperm produced?
Seminiferous tubes
What does testosterone do?
Stimulates sperm production by acting on the seminiferous tubules
In females, what does follicle stimulating hormone do?
Stimulates the development of the follicle and the production of oestrogen.
In females, what does luteinising hormone do?
Stimulates ovulation and the development of the corpus luteum.
What is the corpus luteum?
Structure that forms after ovulation. Secretes progesterone. Forms from empty follicle
What is a Graafian follicle?
Fully mature follicle with a ready-to-release ovum
What does progesterone do?
Promotes the vascularisation of the endometrium and inhibits FSH and LH
What does oestrogen do?
Secreted by the growing follicle. Builds the endometrium
Where does fertilisation take place?
Oviduct
What is vascularisatiom?
The growing of blood vessels through the endometrium
Why is only one ova released at a time?
FSH triggers the development of a follicle and that follicle releases oestrogen which inhibits the FSH and prevents another ova being developed.
What occurs during the Follicular Phase?
FSH is released
FSH stimulates the development of a follicle
Follicle secrets oestrogen
Oestrogen inhibits FSH
Oestrogen builds the endometrium preparing it for implantation
Peak level of oestrogen causes the release of luteinising hormone (LH)
LH trigger ovulation
What is phase 1 of the menstrual cycle called?
The Follicular Phase
What occurs during the Luteal Phase?
Ovulation occurs
Empty follicle develops in a corpus luteum
Corpus luteum secretes progesterone
Progesterone further develops the endometrium and vascularises it
If fertilisation occurs, corpus luteum does not regenerate and progesterone levels remain high
If fertilisation does not occur, corpus luteum degenerates, progesterone levels drop, menstruation occurs
What is phase 2 of the menstrual cycle called?
The luteal phase
What happens during ovulation?
Ovum is released from follicle in the ovary
What happens when oestrogen levels peak?
Release of luteinising hormone and ovulation
What happens at day 14 in the menstrual cycle?
LH is released and ovulation begins
What inhibits FSH and LH?
Oestrogen and Progesterone
What is the negative feedback cycle in male hormones?
High levels of testosterone inhibit the production of FSH and ICSH in the pituitary gland
What are contraceptives used for?
Avoid unwanted pregnancies
Give examples of chemical contraceptives…
Morning After Pill - taken after unprotected sex to prevent implantation if fertilisation occurs.
Mini pills - contains synthetic progesterone, causes mucus to thicken reducing sperms ability to reach ovum
What are the side effects of the mini-pill?
Mood swings, must been taken daily, weight gain, breast tenderness. irregular menstrual cycles
Give examples of physical methods of contraceptives…
Condoms Diaphragm Cervical cap IUD Vasectomy Tubal Ligation
What reasons are there for infertility?
- Ovulation Failure
- Low Sperm Count
- Uterine Blockages
- Implantation Failure
What treatment is there for ovulation failure?
Drugs that prevent the negative feedback effect of oestrogen on FSH and ICSH, causing multiple eggs to mature at once, referred to as ‘super-ovulation’
Why is artificial insemination used and how?
- Used when a male has a low sperm count
- Sperm is collected and processed in a lab
- Semen are artificially injected into the uterus to increase chances of fertilisation
Why would sperm be processed in the lab for artificial insemination?
To ensure only viable sperm are used
When would a sperm donor be used?
When the male is sterile
When is intra-cytoplasmic sperm injection used, and how does it work?
- Used when a male has a low sperm count or defective sperm
- The head of a sperm is artificially injected into an ovum to achieve fertilisation
What is Intra-Vitro Fertilisation?
- IVF is when the ovum and sperm are fertilised outside outside the body
When does menstruation take place and what occurs during it?
- Occurs during days 1-7
- Endometrium breaks down
What is Pre-Implantation Genetic Diagnosis?
- Before IVF, 1 or 2 cells are removed and are tested for genetic abnormalities
- Focus on known chromosomal abnormalities and gene defects
What is Ante-Natal Screening?
Tests which are carried out while the baby is developing to monitor the health of the mother and foetus.
Give examples of Ante-natal screening
- Ultrasound imaging
- Blood and Urine Tests
- Diagnostic Testing
What are the two types of ultrasound imaging?
- Dating scan
- Anomaly scan
When is a dating scan carried out and what does it do?
- 8 to 14 weeks
- used to determine the stage of pregnancy and provide a due date
When is an anomaly scan carried out and what does it do?
- 18 to 20 weeks
- Used to determine presence of serious anomalies
Why are blood and urine carried out?
- Risk assessment for genetic disorders in the foetus
- routine check for marker chemicals
What happens if a blood or urine test is carried out at the wrong time?
can show a false positive
What is diagnostic testing used to do?
- 100% accurate
- shows the presence or absence of a specific condition/disorder
- chronic villus sampling
- amniocentesis
What is karyotyping?
A visual display of chromosome complement to check for chromosome disorders
What does an ultrasound show?
Provides an image of the growing foetus
How does an ultrasound work?
Bounces high frequency waves against the internal structures of the abdomen and creating an image on a computer screen
Give examples of diagnostic tests
- Amniocentesis
- Chronic Villus Sampling
Why are diagnostic tests carried out?
So the mother can make an informed choice about keeping or terminating the child
When is amniocentesis carried out and what are the risks?
- Carried out between 16-18 weeks
- Small risk of miscarriage
- Allows karyotyping