Unit 2 part 1

Question 1

In what layer are the opacities in infectious crystalline keratopathy found?

Answer 1

Stroma

Question 2

In what layer are the opacities in filamentary keratopathy found?

Answer 2

Epithelial

Question 3

What is the most commonly associated pathogen in infectious crystalline keratopathy?

Answer 3

Steptococcus viridans

Question 4

What is the general cause for infectious crystalline keratopathy?

Answer 4

Long term steroid use

Question 5

What causes thygeson superficial punctate keratitis?

Answer 5

Idiopathic

Question 6

How is infectious crystalline keratopathy treated?

Answer 6

Topical antibiotics

Question 7

How is Thygeson superfical punctate keratitis treated?

Answer 7

Lubricants and steroids initially followed by bandage CL and PTK

Question 8

What are the symptoms of Thygeson superficial keratitis?

Answer 8

irritation and watering

Question 9

What are the symptoms of filamentary keratopathy?

Answer 9

Photophobia, dicomfort and redness

Question 10

What is the treatment of filamentary keratopathy?

Answer 10

Treat underlying cause, remove filaments, use mucolytics, hypotonic saline, intensive lubrication , bandage cl, NSAI drops

Question 11

What are the causes of filamentary keratopathy

Answer 11

Aqueous deficiency, CL overwear, REES, eye closure

Question 12

What is the difference between a corneal dystrophy and corneal keratopathies?

Answer 12

Dystrophies are bilateral, genetically determined, progressive.

Question 13

In what layer is Cogan dystrophy found?

Answer 13

Epithelial

Question 14

What else is Cogan’s dystrophy called?

Answer 14

Map/dot, fingerprint

Question 15

At what stage of life is Cogan diagnosed?

Answer 15

2/3rd decade

Question 16

What symptoms are there with Cogan’s dysrophy?

Answer 16

Often asymptomatic but if symptomatic then REES without history of trauma

Question 17

What is the histological appearance of Cogan’s?

Answer 17

Fibril proten deposits between basement mebrane and bowman’s layer.

Question 18

What layer does Meesman dystrophy affect?

Answer 18

Epithelial

Question 19

What is the histological appearance of Meesman?

Answer 19

Irregular thickening of basement membrance of epithelium with tiny intra-epithelial cysts.

Question 20

What are the symptoms of Meesman?

Answer 20

Asymptomatic or mild REES with mild blurring

Question 21

Which layer do Reis-Buckler and Thiele-Behnke corneal dystrophy affect?

Answer 21

Bowman’s layer

Question 22

What is the histological appearance in Reis-Buckler?

Answer 22

Bowman’s layer is replaced by connective tissue bands.

Question 23

What are the symptoms of Reis-Buckler?

Answer 23

Reduced sensitivity, reduced vision (can cause severe impairment), severe REES

Question 24

What is the treatment of Reis-Buckler

Answer 24

As per REES, mild steroids, PTK works in some patients

Question 25

What are the other names of Thiele-Behnke?

Answer 25

Honeycomb-shaped corneal dystrophy/corneal basement dystrophyt type 2

Question 26

Which is the most severe Reis-Buckler or Thiele-Behnke

Answer 26

Reis-Buckler

Question 27

What is the clinical appearance of Reis-Buckler?

Answer 27

geographic sub-epithelial opacities centrally that increase with age

Question 28

What is the clinical appearance of Thiele-Behnke?

Answer 28

Honeycomb-shaped corneal dystophy

Question 29

Which layer does lattice dystrophy affect?

Answer 29

Stroma

Question 30

Which deposits are involved in lattice dystrophy?

Answer 30

Progressive deposition of amyloid (Amy's lace)

Question 31

Which is the most dangerous subset of lattice degeneration and why?

Answer 31

Type 2 as amyloid is deposited elsewhere

Question 32

What do the deposits in lattice degeneration look like?

Answer 32

Fibre like deposits