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Anterior Segment > Unit 2 - corneal keratopathies part 2 > Flashcards

Unit 2 - corneal keratopathies part 2 Flashcards

1
Q

What are the symptoms of lattice degeneration?

A

REES.

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2
Q

What deposits occur in granular dystrophy and where?

A

hyaline (means glass like material in sand i.e. grains) in stroma

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3
Q

What do the deposits in granular dystrophy look like?

A

white crumb-like opacities in an otherwise clear stroma, starts centrally

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4
Q

How does granular dystrophy present?

A

REES, recurrences are common

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5
Q

What deposits occur in avellino dystrophy?

A

both hyaline and amyloid (I’ll ‘ave both)

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6
Q

What is the clinical appearance in avellino dystrophy?

A

crumb and fibre like opacities

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7
Q

What treatment is required in avellino dystrophy?

A

None

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8
Q

What is different about macular dystrophy?

A

It is AR not AD

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9
Q

What deposits do you get in macular dystrophy?

A

glycosaminoglycan deposits

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10
Q

What do the deposits look like in macular dystrophy?

A

Ill defined grey/whitish lesions in stroma. Corneal haziness around lesions. Could involve full-thickness of stroma but usually anterior and central.

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11
Q

What are the symptoms of macular corneal dystrophy?

A

Sensation is reduced, gradual reduction in vision

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12
Q

What is the treatment of macular dystrophy?

A

PK or lamellar keratoplasty, recurrence is rare

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13
Q

What is deposited in Schnyder’s crystalline dystrophy?

A

Phospholipid and cholesterol deposits

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14
Q

How may Schnyder’s dystrophy present?

A

Prominent arcus and diffuse haze in childhood

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15
Q

What systemic checks need to be made with Schnyder’s dystrophy?

A

Fasting lipids

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16
Q

What are the symptoms of Fuch’s

A

vision worse in the morning

17
Q

What is the incidence of Fuch’s in female:men?

A

4:1

18
Q

What is the pathology in Fuch’s?

A

the endothelial tight junctions don’t work very well leading to corneal oedema

19
Q

What is the treatment of Fuch’s?

A

DSAEK or DMEK, hypertonic saline, BCL, lubricants, topical ABX, cycloplegia

20
Q

What other ocular associations are there with Fuch’s?

A

POAG

21
Q

What ocular associates are there with Posterior polymorphous corneal dystrophy?

A

Iris abnormalities, glaucoma and alport syndrome

22
Q

What is the appearance of Posterior polymorphous dystrophy?

A

cluster or lines of haze in posterior cornea

23
Q

What is the difference between type 1 and 2 congenital endothelial corneal dystrophy?

A

Type 1 is AD (mild corneal odemea from infancy, patient is photophobic), Type 2 is AR (more common, more severe and associated with deafness and nystagmus)

24
Q

What treatment is required in posterior polymorphouse corneal dystrophy?

A

Usually asymptomatic so no treatment

Anterior Segment (5 decks)

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