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Pharmacotherapeutics > Unit 2: Lesson 1- PNS > Flashcards

Unit 2: Lesson 1- PNS Flashcards

1
Q

What are the two major divisions of the peripheral nervous system

A

Somatic nervous system

Autonomic nervous system

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2
Q

Bodily functions, “fight or flight”

A

Autonomic nervous system

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3
Q

Skeletal muscle, voluntary muscle movement

A

Somatic nervous system

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4
Q

What are the 3 major subtypes of cholinergic receptors

A

Nicotinic (N)
Nicotinic (m)
Mucarinic

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5
Q

When we see cholinergic receptors we should also think of what system

A

Parasympathetic system

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6
Q

What receptor subtype has Location: in all autonomic nervous system ganglia and the adrenal medulla

A

Nicotinic (N)

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7
Q

What receptor subtype has Response to receptor activation- Stimulation of parasympathetic and sympathetic postganglionic nerves

A

Nicotinic (N)

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8
Q

What receptor subtype has Location- neuromuscular junction

A

Nicotinic (M)

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9
Q

What receptor subtype has Response to receptor activation- contraction of skeletal muscle

A

Nicotinic (M)

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10
Q

What receptor subtype has Location- all parasympathetic target organs

A

Mucarinic

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11
Q

What are the parasympathetic target organs

A 
Eye
Heart 
Lung
Bladder 
GI tract 
Sweat glands
Sex organs
Blood vessels
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12
Q

How does the eye respond to cholinergic receptor activation

A
  • contraction of ciliary muscle focuses the lens for near vision; Contraction of the iris sphincter muscle causes miosis (decreased pupil diameter)
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13
Q

How does the heart respond to cholinergic receptor activation

A

decreased rate

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14
Q

What parasympathetic target organ responds to cholinergic receptor activation by constricting bronchi and Promoting secretions

A

lungs

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15
Q

What parasympathetic target organ responds to cholinergic receptor activation by contraction of detrusor increases bladder pressure; Relations of trigone and sphincter allows urine to leave the bladder; Coordinated contraction of detrusor and relaxation of trigone and sphincter causes voiding of the organ

A

Bladder

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16
Q

How does the GI tract respond to cholinergic receptor activation

A

salivation, increased gastric secretions, increased intestinal tone and motility, defecation

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17
Q

What parasympathetic target organ responds to cholinergic receptor activation by generalized sweating

A

sweat glands

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18
Q

How does the sex organs respond to cholinergic receptor activation

A

Erection

19
Q

What parasympathetic target organ responds to cholinergic receptor activation with vasodilation

A

Blood vessels

20
Q

What are the receptor types of peripheral adrenergic receptors

A 
Alpha (1)
Alpha (2)
Beta (1)
Beta (2)
Dopamine
21
Q

What locations are associated with Alpha (1)

A 
Eye
Arteriole (Skin, Viscera, Mucous Membranes)
Veins
Sex organs (males)
Prostatic capsule 
Bladder
22
Q

When we think of the adrenergic receptors we should also think of the ____ ____

A

Sympathetic system

23
Q

How does the eye respond to adrenergic receptor activation

A

contraction of the radial muscle of the iris causes mydriasis (increased pupil size)

24
Q

How do arterioles respond to adrenergic receptor activation

A

constriction

25
Q

How do arterioles respond to adrenergic receptor activation

A

constriction

26
Q

How does male sex organs respond to adrenergic receptor activation

A

ejaculation

27
Q

How does prostatic capsule respond to adrenergic receptor activation

A

contraction

28
Q

How does the bladder respond to adrenergic receptor activation

A

contraction of trigone and sphincter

29
Q

What locations are associated with receptor subtype Alpha (2)

A

Presynaptic nerve terminals

30
Q

How does the presynaptic nerve terminals respond to adrenergic receptor

A

inhibition of transmitter release

31
Q

Beta (1) receptors are located in the ______ and ______

A

Heart

Kidney

32
Q

Beta (1): How does the heart respond to adrenergic receptor activation

A

increased rate, increased force of contraction, increased AV conduction velocity

33
Q

Where are Beta (2) receptors located

A 
Arterioles (heart, lungs, skeletal muscles)
Bronchi
Uterus
Liver
Skeletal muscle
34
Q

Beta (2): how does the arterioles respond to adrenergic receptor activation

A

dilation

35
Q

Beta (2): how does bronchi respond to adrenergic receptor activation

A

dilation

36
Q

Beta (2): how does the uterus respond to adrenergic receptor activation

A

relaxation

37
Q

Beta (2): how does the liver respond to adrenergic receptor activation

A

Glycogenolysis

38
Q

Beta (2): how does the skeletal muscle respond to adrenergic receptor activation

A

Enhanced contraction, glycogenolysis

39
Q

Beta (1): How do the kidneys respond to adrenergic receptor activation

A

release of rennin

40
Q

Which receptors does epinephrine activate

A

Alpha1
Alpha2
Beta1
Beta2

41
Q

Which receptors does norepinephrine activate

A

Alpha1
Alpha2
Beta1

42
Q

Which receptors do dopamine activate

A

Alpha1
Beta1
Dopamine

43
Q

What are the two divisions of the autonomic nervous system

A

sympathetic nervous system

parasympathetic nervous system

Pharmacotherapeutics (6 decks)

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