Unit 2: Lesson 1- PNS Flashcards
What are the two major divisions of the peripheral nervous system
Somatic nervous system
Autonomic nervous system
Bodily functions, “fight or flight”
Autonomic nervous system
Skeletal muscle, voluntary muscle movement
Somatic nervous system
What are the 3 major subtypes of cholinergic receptors
Nicotinic (N)
Nicotinic (m)
Mucarinic
When we see cholinergic receptors we should also think of what system
Parasympathetic system
What receptor subtype has Location: in all autonomic nervous system ganglia and the adrenal medulla
Nicotinic (N)
What receptor subtype has Response to receptor activation- Stimulation of parasympathetic and sympathetic postganglionic nerves
Nicotinic (N)
What receptor subtype has Location- neuromuscular junction
Nicotinic (M)
What receptor subtype has Response to receptor activation- contraction of skeletal muscle
Nicotinic (M)
What receptor subtype has Location- all parasympathetic target organs
Mucarinic
What are the parasympathetic target organs
Eye Heart Lung Bladder GI tract Sweat glands Sex organs Blood vessels
How does the eye respond to cholinergic receptor activation
- contraction of ciliary muscle focuses the lens for near vision; Contraction of the iris sphincter muscle causes miosis (decreased pupil diameter)
How does the heart respond to cholinergic receptor activation
decreased rate
What parasympathetic target organ responds to cholinergic receptor activation by constricting bronchi and Promoting secretions
lungs
What parasympathetic target organ responds to cholinergic receptor activation by contraction of detrusor increases bladder pressure; Relations of trigone and sphincter allows urine to leave the bladder; Coordinated contraction of detrusor and relaxation of trigone and sphincter causes voiding of the organ
Bladder
How does the GI tract respond to cholinergic receptor activation
salivation, increased gastric secretions, increased intestinal tone and motility, defecation
What parasympathetic target organ responds to cholinergic receptor activation by generalized sweating
sweat glands
How does the sex organs respond to cholinergic receptor activation
Erection
What parasympathetic target organ responds to cholinergic receptor activation with vasodilation
Blood vessels
What are the receptor types of peripheral adrenergic receptors
Alpha (1) Alpha (2) Beta (1) Beta (2) Dopamine
What locations are associated with Alpha (1)
Eye Arteriole (Skin, Viscera, Mucous Membranes) Veins Sex organs (males) Prostatic capsule Bladder
When we think of the adrenergic receptors we should also think of the ____ ____
Sympathetic system
How does the eye respond to adrenergic receptor activation
contraction of the radial muscle of the iris causes mydriasis (increased pupil size)
How do arterioles respond to adrenergic receptor activation
constriction
How do arterioles respond to adrenergic receptor activation
constriction
How does male sex organs respond to adrenergic receptor activation
ejaculation
How does prostatic capsule respond to adrenergic receptor activation
contraction
How does the bladder respond to adrenergic receptor activation
contraction of trigone and sphincter
What locations are associated with receptor subtype Alpha (2)
Presynaptic nerve terminals
How does the presynaptic nerve terminals respond to adrenergic receptor
inhibition of transmitter release
Beta (1) receptors are located in the ______ and ______
Heart
Kidney
Beta (1): How does the heart respond to adrenergic receptor activation
increased rate, increased force of contraction, increased AV conduction velocity
Where are Beta (2) receptors located
Arterioles (heart, lungs, skeletal muscles) Bronchi Uterus Liver Skeletal muscle
Beta (2): how does the arterioles respond to adrenergic receptor activation
dilation
Beta (2): how does bronchi respond to adrenergic receptor activation
dilation
Beta (2): how does the uterus respond to adrenergic receptor activation
relaxation
Beta (2): how does the liver respond to adrenergic receptor activation
Glycogenolysis
Beta (2): how does the skeletal muscle respond to adrenergic receptor activation
Enhanced contraction, glycogenolysis
Beta (1): How do the kidneys respond to adrenergic receptor activation
release of rennin
Which receptors does epinephrine activate
Alpha1
Alpha2
Beta1
Beta2
Which receptors does norepinephrine activate
Alpha1
Alpha2
Beta1
Which receptors do dopamine activate
Alpha1
Beta1
Dopamine
What are the two divisions of the autonomic nervous system
sympathetic nervous system
parasympathetic nervous system
