CNS Flashcards
List 3 ways neurotransmitters are cleared from the synapse
reuptake,
enzymatic degradation
diffusion
What happens during reuptake?
reabsorption of the neurotransmitter occurs
What is enzymatic degradation?
destruction of the neurotransmitter with special chemicals known as enzymes
What happens during diffusion?
The neurotransmitter becomes detached from the receptor and drifts out of the synaptic cleft
List 5 major CNS neurotransmitters?
Acetylcholine, GABA, Glutamate, dopamine, norepinephrine, seretonin
What neurotransmitter is a cholinergic associated with Alzheimer’s?
Acetylcholine
Glutamate is an amino acid responsible for
the biosynthesis of proteins
GABA is an amino acid associated with
anxiety and muscle tone
What amino acid relaxes/slows processes in the brain?
GABA
What are 3 monoamines?
dopamine, serotonin, norepinephrine
Dopamine regulates
attention concentration pleasure energy motivation mood muscle movement
Mood, alertness, concentration and energy are regulated by
Norepinephrine
Serotonin regulates
mood
anxiety
sex
appetite
Explain the statement “From a therapeutic perspective, the blood-brainbarrier is a mixed blessing”
The BBB protects the brain from injury by potentially toxic substances, but it can also be a significant obstacle to entry of therapeutic agents
Identify the four lobes of the brain
Frontal Lobe
Parietal Lobe
Occipital Lobe
Temporal Lobe