Unit 2-4 Flashcards
Neurobiological term for taste
Gustation
Neurobiological term for smell
Olfaction
Papillae
Bumps we can see and feel. Increase surface area of tonight’s for taste receptors
3 types of papillae
1.Circumvallate (back)
2. Foliate (middle)
3. Fungiform (front)
Taste buds
Structures within papillae. Contain receptors that transducer taste info
5 taste
- Sweet
- Salty
- Sour
- Bitter
- Umami
Flavor
Combinations of taste and smells that are characteristics of specific foods
Tongue Sensory Modalities (3)
- temperature receptors - On tongue to detect hotness, spiciness, coldness, Min times of food
- Touch receptors - evaluation of food source
- Pain receptors - injury/ damage
Methods for transduction of the 5 tastes (2)
- Ionotropic (ion channels) : salt and sour
- Metabotropic : sweet, bitter, umami
Detecting salt (NaCl)
Sodium channels: Na+ ions formed, depolarizes taste receptor cell
Chlorine ion (Cl-) detect and pass (mediates unpleasant tests of excess salt)
Detecting sour
Acidity, excess hydrogen ions (H+), hydrogen ion channels
Metabotropic method
Taste receptor 1 (TR1), Taste Receptor 2 (TR2) have subtypes and combinations for sweet, bitter, umami
Savory receptor
T1R1 + T1R3, amino acids = ligands
Sweet receptor
T1R2/T1R3, bind to sucrose (natural) and saccharin (artificial)
Bitter receptors
T2Rs, over 30, poison detection system
Taste projection and processing (3)
- Taste info projected via cranial nerves
- Proceeds through solitary tract to thalamus
- Then to gustatory cortex to perceive taste
Cell types and structures important for transiting odors (3)
- Olfactory receptor (extend cilia down into olfactory epithelium - lined with mucus to trap and dissolve odors)
- Glomerulus (receptors for the same odor project here)
- Mitral cells (glomerulus hones message and conveys it here)
Olfactory receptors are
Metabotropic (400)
Olfactory neurons produced by
Adult neurogenesis, can regenerate
Areas in brain responsible for olfactory processing (4)
- Hypothalamus
- Hippocampus
- Amygdala
- Prepyriform cortex (primary olfactory cortex)
Vomeronasal system
Detect pheromones for potential mate
Project to accessory olfactory bulb to the Limbic system (emotion and sex)
Vomeronasal system controversy with humans
Genetics = no (contain genes but are not functional)
Behavior = yes (synced cycles, women’s tears change testosterone levels in men)
Pathology for olfactory system
Reduces with age, loss of smell = neurodegenerative disease (Parkinson’s, Alzheimer’s), viral infections kill olfactory neurons