Unit 2 Flashcards

1
Q

Brand: Advil

A

Generic: ibuprofen
indication: antipyretic (fever reducer), analgesic
Drug class: NSAID

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Brand: Desyrel

A

Generic: trazodone
indication: depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Brand: Toprol-XL

A

Generic: metoprolol succinate
induction: HTN
drug class: beta blocker
fun fact: beta blockers end in -lol or -olol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Brand: Coumadin

A

Generic: warfarin
indication: anticoagulant (blood thinner)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Brand: Cymbalta

A

Generic: duloxetine
indication: depression
fun fact: drug slogan- “depression hurts, cymbalta can help”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Brand: Flonase

A

Generic: fluticasone
indication: seasonal allergies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Brand: Singulair

A

Generic: montelukast
indication: allergies, asthma
drug class: leukotriene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Brand: Microzide

A

Generic: hydrochlorothiazide (HTCZ)
indication: HTN, edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Brand: Advair

A

Generic: fluticasone/ salmeterol
indication: asthma, COPD, emphysema
fun fact: comes in a diskus drug form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Brand: Percocet

A

Generic: APAP, oxycodone
indication: analgesic C-11

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Brand: Bactrim

A

Generic: sulfamethoxazole/trimethoprim(SMX/TMP) Indication: bacterial infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Brand: vyvanse

A

Generic: lisdexamfetamine
indication: ADHD C-11
fun fact: C-11 have no refills

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Assigned by the international Union of pure and applied chemistry (IUPAC). these names are only used by chemist and researchers. Too complicated for everyday use.

A

Chemical Name

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

The drug company along with the United States adopted names (USAN) council determines the second name that is used by healthcare providers.

A

Generic Name

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

When the FDA gives final approval for marketing, the drug company creates this third name. This becomes a trademark.

A

Trade, Brand, or Proprietary Name

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Test drugs to determine its effectiveness and safety.

A

Food and Drug Administration (FDA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Chemical analysis of a drug done in a laboratory in test tubes

A

In vitro

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Refers to testing done on animals or humans

A

In vivo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Why is animal testing done before human testing?

A

To determine side effects, toxic effects, addictions, etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Describes the mechanism of action by which the drug produces its effect based on time and dose

A

Pharmacodynamics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

The number of animals who respond or do not respond to the drug and at what dose

A

Frequency distribution curve

22
Q

The time required for the drug level in the blood decrease from 100% to 50%. The shorter the drugs half-life, the more frequently it must be given.

23
Q

The relative margin of safety between the dose and that produces the therapeutic effect and the dose that produces a lethal effect in animals.

A

Therapeutic index (TI)

24
Q

Why do we want to take drugs that have a higher TI?

A

Because it indicates that there is a high margin of safety

25
Phase 1
-10 to 100 healthy volunteers -Used to study the safe dose range -evaluate side effects -and establish a final correct dose -takes 1-1 ½ years
26
Phase 2
-50 to 100 patients who have the disease that the drug will treat -Help to determine the extinct of his therapeutic effect -Usually takes 2 years
27
Phase 3
-1000 of ill patients in the exact manner that it will be used once in the market -3 years to complete
28
Movement of the drug through the body during absorption, distribution, metabolism, and excretion are also studied during phase 1
Pharmacokinetics
29
After the animal studies are complete, the drug company submits, an investigational new drug (IND) application to the FDA to request permission to test the drug and humans
3 phases of testing
30
Performed with the drug and the placebo
double-blind studies
31
The patient’s taking the placebo are known as what?
The control group
32
On average, how long does it take for a drug to go from creation to drug testing to market?
12 years
33
How are drugs, discovered or created?
Ancient sources, chemical discovered in the environment, or chemical from molecular manipulation of drug already in
34
A drug that has undergone molecular manipulation
isomer
35
New chemical can be created through genetic manipulation how?
Gene splicing or recombinant DNA (rDNA)
36
The marketing and advertising of RX drugs is regulated by who?
The FDA based on the food, drug, and cosmetic act
37
The marketing of OTC drugs is regulated by who?
The federal trade commission
38
How did drug companies used to advertise?
Used to advertise in medical journals, and doctor visits
39
Sales reps can do what While pharmacies can’t do what when it comes to pharmaceutical sales?
Sales reps can take drug samples to the doctors office to dispense to patients, but pharmacy do not distribute samples
40
What are things that pharmaceutical sales can do today?
Now, direct to consumer marketing has become common as in magazine ads, television, and social media
41
What will cause the FDA to withdraw a medication from the market?
If deaths are involved
42
What is Medwatch?
Medwatch is the FDA safety information and adverse event reporting system on the Internet, where healthcare professions and consumers can report adverse drug effects
43
Usually done because of LOT manufacturing defects
Drug recalls
44
What are the three reasons that a drug might be recalled?
1. The drug does not contain the correct amount of active ingredient. 2. The drug does not remain stable until it’s expiration date. 3. The drug is contaminated.
45
What are some hospital pharmacy supplies?
Main IV bag, syringe and needle w/ safety cap, and sharps container
46
A line or indentation that is found down the middle of the tablet that allows for easier cutting
Score
47
What is the red most left side of a IV bag called? and what is the white most right most part on a IV bag called?
The red left part is the entry port, while the white right part is the IV port that enters the vein
48
Rx is what?
Prescription (hard copy)
49
A glass mortar and pestle would be used to mix what?
Liquids
50
A porcelain mortar and pestle is used to blend what?
Powders