Unit 2 Flashcards
Brand: Advil
Generic: ibuprofen
indication: antipyretic (fever reducer), analgesic
Drug class: NSAID
Brand: Desyrel
Generic: trazodone
indication: depression
Brand: Toprol-XL
Generic: metoprolol succinate
induction: HTN
drug class: beta blocker
fun fact: beta blockers end in -lol or -olol
Brand: Coumadin
Generic: warfarin
indication: anticoagulant (blood thinner)
Brand: Cymbalta
Generic: duloxetine
indication: depression
fun fact: drug slogan- “depression hurts, cymbalta can help”
Brand: Flonase
Generic: fluticasone
indication: seasonal allergies
Brand: Singulair
Generic: montelukast
indication: allergies, asthma
drug class: leukotriene
Brand: Microzide
Generic: hydrochlorothiazide (HTCZ)
indication: HTN, edema
Brand: Advair
Generic: fluticasone/ salmeterol
indication: asthma, COPD, emphysema
fun fact: comes in a diskus drug form
Brand: Percocet
Generic: APAP, oxycodone
indication: analgesic C-11
Brand: Bactrim
Generic: sulfamethoxazole/trimethoprim(SMX/TMP) Indication: bacterial infection
Brand: vyvanse
Generic: lisdexamfetamine
indication: ADHD C-11
fun fact: C-11 have no refills
Assigned by the international Union of pure and applied chemistry (IUPAC). these names are only used by chemist and researchers. Too complicated for everyday use.
Chemical Name
The drug company along with the United States adopted names (USAN) council determines the second name that is used by healthcare providers.
Generic Name
When the FDA gives final approval for marketing, the drug company creates this third name. This becomes a trademark.
Trade, Brand, or Proprietary Name
Test drugs to determine its effectiveness and safety.
Food and Drug Administration (FDA)
Chemical analysis of a drug done in a laboratory in test tubes
In vitro
Refers to testing done on animals or humans
In vivo
Why is animal testing done before human testing?
To determine side effects, toxic effects, addictions, etc.
Describes the mechanism of action by which the drug produces its effect based on time and dose
Pharmacodynamics
The number of animals who respond or do not respond to the drug and at what dose
Frequency distribution curve
The time required for the drug level in the blood decrease from 100% to 50%. The shorter the drugs half-life, the more frequently it must be given.
Half-life
The relative margin of safety between the dose and that produces the therapeutic effect and the dose that produces a lethal effect in animals.
Therapeutic index (TI)
Why do we want to take drugs that have a higher TI?
Because it indicates that there is a high margin of safety