Rheumatoid Arthritis Flashcards
What causes rheumatoid arthritis?
Autoimmune response in which the body’s own immune system attacks the joints, leading to inflammation, pain, and swelling.
List some common side effects of salicylate drugs, NSAIDs, COX-2 inhibitor drugs, and corticosteroid drugs.
- Upper stomach pain
- Headache
- Heart risks
- Nausea
- Kidney issues
About how much real gold is contained in a gold compound drug?
~24-60%
What is the route of administration for Auranofin?
Oral
What is the generic name for Gold Sodium Thiomalate?
Aurothiomalate
Name contraindications for adalimumab.
- Severe infections
- Heart failure
- Hypersensitivity to drug
What are the two routes of administration for golimumab?
- Subcutaneous injection
- Intravenous infusion
What is the mechanism of action for rituximab?
Targets CD20 antigen found on B lymphocytes.
List the precautions for tocilizumab.
- Increased infection risk
- Liver toxicity
- GI perforations
What is the brand name for Abatacept?
Orencia
True or false: Kineret blocks the activity of interleukin?
True
What is the fun fact for Rheumatrex Dose Pack?
This medication has been discontinued, but generic equivalents are available.
How does Enbrel work to reduce inflammation?
Reduces inflammation by attaching to tumor necrosis factor (TNF) proteins, blocking their activity.
If you are allergic to hydroxychloroquine or chloroquine, you should not take what drug?
Plaquenil
What is the indication for Leflunomide?
Treatment of active rheumatoid arthritis as a “disease-modifying antirheumatic drug” (DMARD) to prevent joint damage.
