unit 1.6 metabolic pathways Flashcards
metabolic pathways are
integrated and controlled pathways of enzyme catalysed reactions in cell
anabolic
build up smaller molecules to form larger ones
requires energy
catabolic
breakdown of larger molecule to form smaller
doesn’t require energy
enzymes are
metabolic pathways are controlled by a absence or present of particular enzyme and regulate rate of reaction of key enzyme
active sites function
substrate have high affinity for active site
products have lower affinity for the active site and so can leave
affinity
the tendency for molecule to bind to enzyme
induced fit
the enzyme will change shape f active site to better fit its substrate- lowers the activation energy
factors affecting the rate of enzyme reaction
temperature
- rise in temp increase the Arte of enzyme toward the optimum
- optimum: where enzyme works at its best
- enzyme can be denatured resulting the active site change shape meaning the substrate no longer fit the site
pH
- enzyme works within ranges of pH values and dont have an optimum
substrate concentration
increase substrate concentration the increases in enzyme activity and reaches a maximum and so levels off
saturated
till active site is occupied by substrate
inhibitors are
reduces the rate of enzyme activity
competitive
inhibitors which competes with substrate for active site
reversible by increasing the substrate concentration
non competitive
inhibitors bind away the active site but results a change of active site
this process ion irreversible
feedback
when the end product in metabolic pathway reach critical condition where it inhibits an enemy earlier in the pathway blocking preventing the synthesis spa end products
