Unit 1.2.b.iv

Question 1

Where are secretory proteins translated and give examples of secretory proteins

Answer 1

Secreted proteins are translated in ribosomes on the RER and enter its lumen.
Peptide hormones and digestive enzymes are examples of secreted proteins.
The proteins move through the Golgi apparatus and are then packaged into secretory vesicles.
These vesicles move to and fuse with the plasma membrane, releasing the proteins out of the cell.

Peptide hormones and digestive enzymes are examples of secreted proteins.

Question 2

What is proteolytic cleavage?

Answer 2

Proteolytic cleavage is another type of post- translational modification. Digestive enzymes are one example of secreted proteins that require proteolytic cleavage to become active.