Unit 1 AOS 1 (2nd Test) Flashcards

1
Q

Adult Stem Cell

A

A cell present in adult tissues that generates replacements for a limited range of cells.

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2
Q

Anaphase

A

A phase of mitosis in which the chromosomes separate and move to opposite ends of the cell.

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3
Q

Apoptosis

A

programmed cell death. process of cell death via a series of steps

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4
Q

Binary Fission

A

A form of reproduction in SINGLE-CELLED organisms (bacteria etc.) where one cell divides into two cells of the same size.

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5
Q

Cancer

A

Disorder in which some of the body’s cells lose the ability to control growth (uncontrolled cell division).

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6
Q

Cell Cycle

A

The regular sequence of growth and division that cells undergo.

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7
Q

Centriole

A

Cell organelle that aids in cell division in animal cells only. Replicated in S phase and moves to opposite ends during mitosis.

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8
Q

Chromatid

A

one of two identical ‘sister’ parts of a duplicated chromosome joined at the centromere.

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9
Q

Cytokinesis

A

Division of the cytoplasm during cell division. Separates the cell into two cells.

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10
Q

Daughter cell

A

The new cell formed as a product of cell division.

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11
Q

DNA Replication

A

The process in which DNA makes a duplicate copy of itself.

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12
Q

Embryo

A

An organism in the earliest stage of development.

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13
Q

Embryonic Stem Cell

A

A stem cell derived from human blastocysts.
Pluripotent, can differentiate into any germ layer.

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14
Q

Enzyme

A

A type of protein that speeds up a chemical reaction in a living thing.

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15
Q

G0 Phase

A

A phase in the cell cycle where the cell is NOT dividing and its DNA is NOT replicating.
RESTING phase of interphase.

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16
Q

G1 Checkpoint

A

Checkpoint at the end of G1 in interphase.
checks for cell size, nutrients, growth factors and DNA damage.

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17
Q

G1 Phase

A

Stage of interphase where the cell grows and almost doubles in size and performs its normal functions to gain energy.

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18
Q

G2 Checkpoint

A

checkpoint at the end of G2 in interphase.
checks there are adequate resources, the cell is large enough, and DNA is duplicated correctly.

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19
Q

G2 Phase

A

The last stage of interphase. Cell undergoes more growth and gains energy.

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20
Q

Germ layer

A

One of the three cell layers (endoderm, mesoderm, ectoderm) present in an embryo.

21
Q

Interphase

A

Cell grows, performs its normal functions and prepares for division.
Consists of G1, S and G2 phases. Longest stage of the cell cycle

22
Q

M Checkpoint

A

Checkpoint at the end of metaphase. Spindle assembly checkpoint.
Mitosis will not continue if chromosomes are not properly aligned or spindles are not correctly attached.

23
Q

Metaphase

A

Second phase of mitosis, where the chromosomes line up across the center of the cell.

24
Q

Mitosis

A

Cell division in which the nucleus divides into nuclei containing the same number of chromosomes.

25
Mitotic Spindle
A structure made of microtubules (formed by centriole) that controls chromosome movement during mitosis. These attach to the centromeres of chromosomes in mitosis.
26
Multipotent
Can only differentiate into a number of closely related cell types. e.g bone marrow stem cells can only differentiate into different types of blood cells.
27
Mutagen
A chemical or physical agent that interacts with DNA and causes a mutation.
28
Neoplasm
New growth (tumor). Can be harmless or cancerous
29
Pluripotent
Cells that are capable of developing into most, but not all, of the body's cell types. e.g human embryonic stem cell.
30
Potency
Potential of a stem cell to differentiate into different cell types.
31
Prophase
First phase in mitosis. Chromosomes become visible, nuclear envelope dissolves, centrioles move to opposite ends and spindles form.
32
S Phase
The synthesis phase of the cell cycle. Where the DNA is replicated in the nucleus.
33
Telomere
DNA at the tips of chromosomes
34
Telophase
The final phase of cell division where the chromatids or chromosomes move to opposite ends of the cell and 2 nuclei membranes are reformed, spindles are dismantled, chromosomes become long and thin again.
35
Tissue Culture
Technique for growing pieces of living tissue in artificial media containing essential salts, nutrients and growth factors.
36
Totipotent
Can make ALL types of specialized cells in the body including embryonic cells.
37
Unipotent
Can only become ONE type of cell
38
Zygote
Diploid cell resulting in fusion of egg and sperm - it enters a 2-week period of rapid cell division and develops into an embryo.
39
Bleb
The bulge in the plasma membrane to form separate apoptotic bodies
40
Apoptotic Body
vesicle containing parts of a dying cell.
41
Binary Fission Steps
1. Cell elongates and DNA is replicated 2. Cell Wall and plasma membrane begin to divide 3. Cross-wall forms completely around divided DNA 4. Cells Seperate
42
Caspases
Family of proteases that cut up proteins and DNA
43
Caspase cascade
Activation of caspases leading to apoptosis
44
Centromere
The area where the chromatids of a chromosome are attached. (in the Center)
45
Death receptor pathway
The pathway of apoptosis. Extrinsic Pathway
46
Germ layers
ectoderm, mesoderm, endoderm
47
Oncogene
cancer causing gene
48
Phagocytic cell
responds to cell damage by engulfing and destroying the cell.