Unit 1 Flashcards

0
Q

Window period of HIV

A

3 weeks to 6 months

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1
Q

Adverse effects with HIV to

A
Hepatotoxicity 
Nephrotoxicity
Osteopenia
Dyslipidemia
Insulin resistance 
Increased CVD
fat redistribution syndrome:
Lipoatrophy: localized subQ fat loss in face, arms, legs and buttocks)
Lipohypertrophy: central visceral fat accumulation in abdomen, breast, buffalo hump)
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3
Q

Viral set point

A

Remaining amount of virus in body after this initial immune response

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4
Q

Phase 1 HIV

A
primary infection (time from infection till the body makes antibodies)
scary window (pt is contagious but doesnt show)
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5
Q

Acute Retroviral syndrome

A
fever
lymphadenopathy
pharyngitis
skin rash
myalgias
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6
Q

Phase 2 HIV

A

Asymptomatic

>500 CD4

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7
Q

Phase 3 HIV

A
symptomatic
200-499 CD4
Fever, chills, night sweats, diarrhea
shingles
cancer
candidadis
peripheral neuropathy
PID
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8
Q

AIDS Phase 4 HIV

A
<14% lymphocyte count
Candidadis (bronchi, trachea, etc)
cervical cancer
cryptococcosis
Encephalopathy
Herpes Simplex
Kaposis sarcoma
PCP
wasting syndrome
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9
Q

EIA (enzyme immunoassay)

A

ID antibodies against HIV. Not definitive

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10
Q

Western blot assay

A

to confirm seropositivity when EIA result is positive

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11
Q

OraSure test

A

Uses saliva to perform EIA antibody (30 min) HIV screening

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12
Q

Tx of HIV infection based on

A

Viral load
CD4 count
clinical condition of pt

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13
Q

Tx for HIV if

A

T cell count 55000 (research says >100000)

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14
Q

Antiretrovirals S/E

A
Increased cholesterol
DIabetes
lipodystrophy
facial wasting
skinny arms and legs
heart disease
peripheral neuropathies
thrombocytopenia
depression
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15
Q

viral load testing every

and when else

A

3-4 months

before initiation and after 2-8 weeks

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16
Q

T cell counts every

A

3-6 months

17
Q

Viral load undetectable

A

16-20 weeks

18
Q

HAART

A

highly active antiretroviral therapy

19
Q

Immunomodulator therapy

A

enhancement of the host immune response (interferons and colony-stimulating factors)

20
Q

Clinical manifestations (HIV)

A
PCP
MAC 
TB
Oral candidiasis
Wasting syndrome
Kaposis sarcome
B-cell lymphomas
HIV encephalopathy
Cryptococcus neoforms
progressive multifocal leukoencephalopathy
CMV
MTB
Toxopasmagondi