Unit 1 (1.5) Flashcards

Nucleic acids (28 cards)

1
Q

What are monomers of nucleic acids?

A

Nucleotides

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2
Q

What are the 3 components of nucleotides

A

Pentose sugar
Organic base
Phosphate group

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3
Q

What are the two types or organic bases

A

Purine and Pyrimidine

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4
Q

What is a purine

A

Class of organic bases
Double ring structure
Includes adenine and guanine

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5
Q

What is a pyrimidine

A

Class of organic bases
Single ring structure
Includes cytosine, thymine, uracil

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6
Q

Describe structure of DNA nucleotide

A

Deoxyribose
Organic base A,T G or C
Phosphate group

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7
Q

Describe the structure of an RNA nucleotide

A

Ribose
Organic base A,U, C or G
Phosphate group

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8
Q

Describe the structure of an ATP nucleotide

A

Ribose
Adenine
Three phosphate groups

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9
Q

Describe the role of ATP

A

Universal energy currency, Hydrolysed to release energy

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10
Q

What is the structure of ATP

A

ATP contains adenine, a ribose sugar, and three phosphates

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11
Q

What is complementary base pairing?

A

Describes how hydrogen bonds form between complementary purine and pyrimidine bases
Two bonds form between A, T or U
Three bonds between G and C

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12
Q

Describe the structure of DNA

A

Double-stranded polymer of nucleotides twisted to form a double helix
Nucleotides joined by phosphodiester bonds
Hydrogen bonds form between complementary base pairs A, T, C and G
Antiparallel strands

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13
Q

Why are the strands of a DNA double helix described as antiparallel

A

The complementary strands run parallel but in opposite directions 5’ to 3’ and 3’ to 5’

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14
Q

Describe the structure of RNA

A

Single-stranded polymer nucleotides
Nucleotides by phosphodiester bonds
Hydrogen bonds from between complementary base pairs A, U C and G

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15
Q

Compare and contrast DNA and RNA

A

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16
Q

What are the three types of RNA found in cells

A

Transfer RNA (tRNA)
Messenger RNA (mRNA)
Ribosomal RNA (rRNA)

17
Q

What is tRNA’s function

A

it carries specific amino acids to the ribosomes

18
Q

What is mRNA’s function

A

Carries genetic information from the nucleus to the ribosomes for synthesis

19
Q

What is rRNA’s function

A

Associates with proteins in the cytoplasm to form ribosomes

20
Q

Describe the triplet code for amino acids

A

A sequence of three nucleotides (codon) on a molecule of DNA or RNA codes for a particular amino acid in protein synthesis

21
Q

What is the genetic code?

A

The rules by which triplets in a DNA base sequence code for the sequence of amino acids in a polypeptide chain.
The genetic code is degenerate, universal and non-overlapping.

22
Q

What is an exon

A

A region of DNA that codes for an amino acid sequence

23
Q

What is an intron

A

A non-coding sequence of DNA that is found between exons

24
Q

What are the two major functions of DNA

A

Protein synthesis and Replication

25
What is protein synthesis
The formation of proteins from amino acids. There are two stages transcription and translation
26
What is transcription
First stage of protein synthesis The formation of pre-mRNA in eukaryotes and mRNA in prokaryotes from a section of the template strand of DNA
27
What happens to the polypeptide after translation?
Further modified by adding carbohydrates, lipids or phosphates Different polypeptides may be combined
27
What is the 'one gene one polypeptide' hypothesis?
The theory that each gene encodes a single protein